Pulmonary Vascular Pathology

A rare case of pulmonary lymphangiectasia associated with CHD

Claudio Henriques, Ana Lai, Helena Andrade, Raquel Pina, Antonio Marinho-da-Silva, Antonio PiresPaediatric Hospital and University Hospital.Portugal Cardiology in the YoungCardiol Young 2022; 32: 132-134DOI: 10.1017/S1047951121002328 AbstractCHD may, at times, occur in the framework of other rare pathologies. These, having similar clinical manifestations, present a diagnostic dilemma for the clinician.The authors present the case of an infant […]

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Pulmonary vein stenosis

Chen-Chih J. Sun, Thomas Doyle, Richard E. RingelUniversity of Maryland.United States Human PathologyHum Pathol 1995; 26: 880-886DOI: 10.1016/0046-8177(95)90011-x AbstractPulmonary vein stenosis (PVS) is a rare disorder. Accurate diagnosis often requires anatomical examination. We report four children with pulmonary vein stenosis. Autopsy showed bilateral lesions in two patients who were thought clinically to have unilateral disease. A diagnosis of PVS was made

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Correlation of Intravascular Ultrasound with Histology in Pediatric Pulmonary Vein Stenosis

Ryan Callahan, Zachary Gauthier, Shuhei Toba, Stephen P. Sanders, Diego Porras, Sara O. VargasBoston Children’s Hospital and Harvard Medical School.United States ChildrenChildren 2021; 8: DOI: 10.3390/children8030193 AbstractPreliminary intravascular ultrasound (IVUS) images of suspected pediatric intraluminal pulmonary vein stenosis (PVS) demonstrate wall thickening. It is unclear how the IVUS-delineated constituents of wall thickening correlate with the histology.

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Lung biopsy in infants with severe bronchopulmonary dysplasia

Danielle A. Callaway, Yifei Wang, Krithika Lingappan, Jennifer E. Pogoriler, Pablo Laje, Kathleen Nilan, Haresh Kirpalani, Huayan ZhangThe Children’s Hospital of Philadelphia. Guangdong Provincial People’s Hospital. McMaster University. Guangzhou Women and Children’s Medical Center.United States, China and Canada Pediatric PulmonologyPediatr Pulmonol 2023; DOI: 10.1002/ppul.26433 AbstractIntroduction: Lung biopsy is infrequently performed in the population of infants with severe

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Acute kidney injury decreases pulmonary vascular growth and alveolarization in neonatal rat pups

Brianna M. Liberio, Gregory Seedorf, Danielle E. Soranno, John R. Montford, Sarah G. Faubel, Andres Hernandez, Steven H. Abman, Jason GienIndiana University School of Medicine. University of Colorado School of Medicine. Rocky Mountain Regional VA Medical Center. United States Pediatric ResearchPediatr Res 2023; DOI: 10.1038/s41390-023-02625-y AbstractBackground: Acute kidney injury (AKI) is common in sick neonates and associated

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Pulmonary Histopathologic Findings in Pediatric Patients After Hematopoietic Stem Cell Transplantation: An Autopsy Study

Nahir Cortes-Santiago, Kalyani R. Patel, Hao Wu, Sara E. Sartain, Saleh Bhar, Manuel Silva-Carmona, Jennifer PogorilerTexas Children’s Hospital and Baylor College of Medicine. Yale School of Medicine and Yale New Haven Hospital. Children’s Hospital of Philadelphia.United States Pediatric and Developmental PathologyPediatr Dev Pathol 2023; DOI: 10.1177/10935266231170101 AbstractBackground: Pathologic characterization of pulmonary complications following hematopoietic stem cell transplantation

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Effect of prenatal diaphragmatic hernia on pulmonary arterial morphology

Andrew V. Stainsby, Philip L. J. DeKoninck, Kelly J. Crossley, Alison Thiel, Megan J. Wallace, James T. Pearson, Aidan J. Kashyap, Michelle K. Croughan, Beth A. Allison, Ryan Hodges, Marta Thio, Andreas W. Flemmer, Erin V. McGillick, Arjan B. te Pas, Stuart B. Hooper, Marcus J. KitchenHudson Institute of Medical Research, Victoria Heart Institute and

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Repetitive schistosoma exposure causes perivascular lung fibrosis and persistent pulmonary hypertension

Rahul Kumar, Michael H. Lee, Biruk Kassa, Dara C. Fonseca Balladares, Claudia Mickael, Linda Sanders, Adam Andruska, Maya Kumar, Edda Spiekerkoetter, Angela Bandeira, Kurt R. Stenmark, Rubin M. Tuder, Brian B. GrahamUniversity of California San Francisco. Zuckerberg San Francisco General Hospital. University of Colorado Anschutz Medical Campus. Stanford University. Universidade de Pernambuco.United States and Brazil

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Review of the Pathologic Characteristics in Myhre Syndrome: Gain-of-Function Pathogenic Variants in SMAD4 cause a Multisystem Fibroproliferative Response

Lois J. Starr, Mark E. Lindsay, Deborah Perry, Gregory Gheewalla, Paul A. VanderLaan, Adnan Majid, Charlie Strange, George-Claudiu Costea, Adrian Lungu, Angela E. LinUniversity of Nebraska Medical Center. Harvard Medical School and MassGeneral Hospital for Children. Massachusetts General Hospital. Methodist Hospital. Tufts University School of Medicine. Beth Israel Deaconess Medical Center. Medical University of South

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Utilizing the Precision-Cut Lung Slice to Study the Contractile Regulation of Airway and Intrapulmonary Arterial Smooth Muscle

Yan Bai, Xingbin AiMassachusetts General Hospital and Harvard Medical School.United States Journal of Visualized ExperimentsJ Vis Exp 2022; DOI: 10.3791/63932 AbstractSmooth muscle cells (SMC) mediate the contraction of the airway and the intrapulmonary artery to modify airflow resistance and pulmonary circulation, respectively, hence playing a critical role in the homeostasis of the pulmonary system. Deregulation of

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