Pulmonary Vascular Pathology

The small-molecule formyl peptide receptor biased agonist, Compound 17b, is a vasodilator and anti-inflammatory in mouse precision-cut lung slices

William R. Studley, Emma Lamanna, Katherine A. Martin, Claudia A. Nold-Perry, Simon G. Royce, Owen L. Woodman, Rebecca H. Ritchie, Cheng Xue Qin, Jane E. BourkeMonash University. Hudson Institute of Medical Research. Baker Heart and Diabetes Institute.Australia British Journal of PharmacologyBr J Pharmacol 2023; DOI: 10.1111/bph.16231 AbstractBackground and purpose: Pulmonary arterial hypertension (PAH), a rare but fatal […]

The small-molecule formyl peptide receptor biased agonist, Compound 17b, is a vasodilator and anti-inflammatory in mouse precision-cut lung slices Read More »

Intrapulmonary arterial contraction assay reveals region-specific deregulation of vasoreactivity to lung injuries

Yan Bai, Guang Li, Laiming Yung, Paul B. Yu, Xingbin AiMassachusetts General Hospital and Harvard Medical School. Brigham and Women’s Hospital. Renmin Hospital and Wuhan University. United States and China American Journal of Physiology Lung Cellular and Molecular PhysiologyAm J Physiol Lung Cell Mol Physiol 2023; 325: L114-L124DOI: 10.1152/ajplung.00293.2022 AbstractIntrapulmonary arteries located in the proximal lung

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Drug-eluting stents ameliorate pulmonary vein stenotic changes in pigs in vivo

Takeshi Furukawa, Masahiko Kishiro, Hideo Fukunaga, Masahiro Ohtsuki, Ken Takahashi, Katsumi Akimoto, Toshiaki Shimizu, Shiori Kawasaki, Toshio KumasakaJuntendo University School of Medicine.Japan Pediatric CardiologyPediatr Cardiol 2010; 31: 773-779DOI: 10.1007/s00246-010-9695-8 AbstractThe outcome of stent implantation for pulmonary vein stenosis (PVS) in children remains poor. Several reports describe placing drug-eluting stents to treat PVS, but their effectiveness remains

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Losartan ameliorates “upstream” pulmonary vein vasculopathy in a piglet model of pulmonary vein stenosis

Jiaquan Zhu, HarukiIde, Yaqin Yana Fu, Anouk-Martine Teichert, Hideyuki Kato, Richard D. Weisel, Jason T. Maynes, John G. Coles, Christopher A. CaldaroneThe Hospital for Sick Children and University of Toronto. Toronto General Hospital. Canada Journal of Thoracic and Cardiovascular SurgeryJ Thorac Cardiovasc Surg 2014; 148: 2550-2557DOI: 10.1016/j.jtcvs.2014.07.050 AbstractObjectives: Pulmonary vein stenosis (PVS) is a relentless disease with

Losartan ameliorates “upstream” pulmonary vein vasculopathy in a piglet model of pulmonary vein stenosis Read More »

An infant with primary pulmonary vein stenosis, associated with fatal occlusion of intraparenchymal small pulmonary veins

Takanari Fujii, Hideshi Tomita, Hiroaki Kise, Kazuto Fujimoto, Kozue Kobayashi, Yoshitaka Watanabe, Takeshi Yamazaki, Takeshi Shimizu, Shunsuke Sakurai, Satoshi Hibino, Junya Iwasaki, Takashi Soga, Shigeru Uemura, Kazuo Itabashi, Shigeo YamakiShowa University Northern Yokohama Hospital. Japanese Research Institute of Pulmonary Vasculature.Japan Journal of Cardiology CasesJ Cardiol Cases 2013; 9: 3-7DOI: 10.1016/j.jccase.2013.08.013 AbstractPrimary pulmonary vein stenosis (PVS) is

An infant with primary pulmonary vein stenosis, associated with fatal occlusion of intraparenchymal small pulmonary veins Read More »

Pulmonary vein stenosis and the pathophysiology of “upstream” pulmonary veins

Hideyuki Kato, Yaqin Yana Fu, Jiaquan Zhu, Shabana Aafaqi, Otto Rahkonen, Cameron Slorach, Alexandra Traister, Chung Ho Leung, David Chiasson, Luc Mertens, Lee Benson, Richard D. Weisel, Boris Hinz, Jason T. Maynes, John G. Coles, Christopher A. CaldaroneHospital for Sick Children and University of Toronto. Toronto General Hospital. Canada Journal of Thoracic and Cardiovascular SurgeryJ

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Lung Pathology in Pediatric Pulmonary Vein Stenosis

Jennifer E. Pogoriler, Thomas J. Kulik, Alicia M. Casey, Christopher W. Baird, Mary P. Mullen, Kathy J. Jenkins, Sara O. VargasBoston Children’s Hospital and Harvard Medical School.United States Pediatric and Developmental PathologyPediatr Develop Pathol 2016; 19: 219-229DOI: 10.2350/15-07-1670-OA.1 AbstractPulmonary vein stenosis is a rare progressive narrowing of the extrapulmonary pulmonary veins, presenting predominantly in infancy and

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Pulmonary hypertension due to left heart disease causes intrapulmonary venous arterialization in rats

Yoshitaka Fujimoto, Takashi Urashima, Fumie Kawachi, Toru Akaike, Yoichiro Kusakari, Hiroyuki Ida, Susumu MinamisawaJikei University School of Medicine.Japan Journal of Thoracic and Cardiovascular SurgeryJ Thorac Cardiovas Surg 2017; 154: 1742-1753DOI: 10.1016/j.jtcvs.2017.06.053 AbstractObjective: A rat model of left atrial stenosis-associated pulmonary hypertension due to left heart diseases was prepared to elucidate its mechanism.Methods: Five-week-old Sprague-Dawley rats were randomly divided

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Paucicellular Fibrointimal Proliferation Characterizes Pediatric Pulmonary Vein Stenosis: Clinicopathologic Analysis of 213 Samples From 97 Patients

Alexandra E. Kovach, Philip M. Magcalas, Christina Ireland, Kerry McEnany, Andre M. Oliveira, Mark W. Kieran, Christopher W. Baird, Kathy Jenkins, MD, Sara O. VargasBoston Children’s Hospital. Dana Farber Cancer Institute. Mayo Clinic.United States American Journal of Surgical PathologyAm J Surg Pathol 2017; 41: 1198-1204DOI: 10.1097/PAS.0000000000000892 AbstractPulmonary vein stenosis (PVS) is a luminal narrowing of extrapulmonary

Paucicellular Fibrointimal Proliferation Characterizes Pediatric Pulmonary Vein Stenosis: Clinicopathologic Analysis of 213 Samples From 97 Patients Read More »

Unilateral congenital pulmonary lymphangiectasis presenting with pneumothorax and an NRAS variant

Majid Al Teneiji, Marie-Anne Brundler, Mary Noseworthy, Kyle C. KurekAlberta Children’s Hospital and University of Calgary. Canada Pediatric PulmonologyPediatr Pulmonol 2021; 56: 2374-2376DOI: 10.1002/ppul.25401 AbstractNo Abstract Available CategoryPrimary Pulmonary Lymphatic DiseaseGenetic Factors Associated with Pulmonary Vascular DiseasePulmonary Vascular Pathology Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Filed (PHiled). Greater than 1-2 years since

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