Class 1. Pulmonary Hypertension Associated With Infection

Clinical phenotypes and mortality predictors in pediatric critical pertussis: A multinational study

Mohammad Alghounaim, Naila A. Shaheen, Abdulrahman Aldaithan, Saif Awlad Thani, Yasser Kazzaz, Abdulla Alfraij, On behalf of the Gulf Pediatric Pertussis Study (GPPS) Group Amiri Hospital, Ministry of Health. King Abdullah International Medical Research Center. King Saud bin Abdulaziz University for Health Sciences. Farwaniya Hospital. Royal Hospital.Kuwait, Saudi Arabia and Oman Journal of Infection and […]

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Case Report: Prolonged extracorporeal membrane oxygenation as a deliberate operative adjunct for tracheobronchial reconstruction in a child with invasive aspergillosis

Marcin Łosin, Wojciech Karolak, Romuald Lango, Witold Rzyman, Monika Rosinski, Weronika Lotkowska, Piotr CzaudernaMedical University of Gdansk and University Clinical Center.Poland Frontiers in PediatricsFront Pediatr 2026; 14: DOI: 10.3389/fped.2026.1843892 AbstractWe report the case of a 6-year-old boy with newly diagnosed type 1 diabetes mellitus presenting in diabetic ketoacidosis, who developed a massive acquired tracheo-esophageal fistula (TEF)

Case Report: Prolonged extracorporeal membrane oxygenation as a deliberate operative adjunct for tracheobronchial reconstruction in a child with invasive aspergillosis Read More »

Unveiling the Link Between COVID-19 and Pulmonary Hypertension

Jad Abdul Khalek, Mohamad Al Hajjar, Zeina Al-Khalil, Jana Salem, Rana Zareef, Fadi Bitar, Mariam ArabiAmerican University of Beirut Medical Center and American University of Beirut.Lebanon Canadian Journal of Infectious Diseases and Medical MicrobiologyCan J Infect Dis Med Microbiol 2026; DOI: 10.1155/cjid/9352258 AbstractIntroduction: The COVID-19 pandemic, caused by the SARS-CoV-2 virus, was first identified in Wuhan, China,

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Critical Pertussis in the PICU: Multinational Study in the Gulf Cooperation Council Region, 2022-2024

Mohammad Alghounaim, Naila A. Shaheen, Aldaithan, Abdulrahman, Saif Awlad Thani, Yasser Kazzar, Abdulla Alfraij, on behalf of the Gulf Pediatric Pertussis Study (GPPS) GroupAmiri Hospital. King Abdullah International Medical Research Center. King Saud bin Abdulaziz University for Health Sciences. Farwaniya Hospital. Ahmadi Hospital. Royal Hospital.  Ministry of National Guard Health Affairs.Kuwait, Saudi Arabia and Oman Pediatric Critical Care

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Early venoarterial extracorporeal membrane oxygenation with airway clearance techniques in severe pertussis with pulmonary hypertension in a two-month-old infant: a case report

Yan Liu, Yaoyao Wu, Wei Yue, Xinyan QiuGuangdong Women and Children Hospital. China International Journal of Emergency MedicineInt J Emerg Med 2026; DOI: 10.1186/s12245-026-01247-5 AbstractBackground: Severe pertussis in young infants can lead to respiratory failure, pulmonary hypertension, and sepsis, and remains difficult to manage when conventional therapies fail. In such cases, extracorporeal membrane oxygenation (ECMO) combined with

Early venoarterial extracorporeal membrane oxygenation with airway clearance techniques in severe pertussis with pulmonary hypertension in a two-month-old infant: a case report Read More »

[Association between adverse outcomes during hospitalization and early postnatal weight changes in term appropriate-for-gestational-age infants with early-onset sepsis]

Shi-Cheng Zeng, Xian-Lu Zhou, Ling-Ling Xiang, Zi-Yu HuaChildren’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, and Chongqing Key Laboratory of Pediatric Metabolism and Inflammatory DiseasesChina Chinese Journal of Contemporary PediatricsZhongguo Dang Dai Er Ke Za Zhi 2026; 28:

[Association between adverse outcomes during hospitalization and early postnatal weight changes in term appropriate-for-gestational-age infants with early-onset sepsis] Read More »

Persistent pulmonary hypertension, neonatal stroke, coagulopathy and multi-organ failure due to severe enterovirus sepsis: two case reports

Arangan Kirubakaran, Kirsty Gray, Thomas Slater, Zoe Cass-Tansey, Amna Alvi, Sundar, Sathiyamurthy, Ujwal Kariholumperial College Healthcare NHS Trust. Hillingdon Hospitals NHS Foundation Trust.United Kingdom BioMedical Central PediatricsBMC Pediatr 2026; DOI: 10.1186/s12887-026-06812-8 AbstractBackground: Disseminated neonatal enteroviral infection is a rare and life-threatening condition with significant multi-organ involvement. It often presents with nonspecific symptoms that may be mistakenly

Persistent pulmonary hypertension, neonatal stroke, coagulopathy and multi-organ failure due to severe enterovirus sepsis: two case reports Read More »

Severe Pertussis During Early Infancy from a High-Altitude Region: Two Clinical Cases and Literature Review

Hongju Chen, Sezhen Baima, Xiaoming Xu, Tao Wang, Jing ShiWest China Second University Hospital, Xizang Hospital, Sichuan, Xizang Autonomous Region Women’s and Children’s Hospital and Sichuan University.China Journal of Clinical MedicineJ Clin Med 2026; 15: DOI: 10.3390/jcm15062211 AbstractObjective: To investigate how the high-altitude environment modifies severe pertussis in young infants and analyze its pathophysiological mechanisms and

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Respiratory Syncytial Virus Infection Triggering a Pulmonary Hypertensive Crisis in a Boy With Prader-Willi Syndrome-Associated Sleep-Disordered Breathing

Mari Tsukahara, Hideaki Yagasaki, Koichi Makino, Tomoaki Sano, Takeshi InukaUniversity of Yamanashi.Japan CureusCureus 2026; 18: DOI: 10.7759/cureus.103890 AbstractPrader-Willi syndrome (PWS) is a multisystem genetic disorder frequently complicated by sleep-disordered breathing, including obstructive sleep apnea. Respiratory infections may precipitate acute decompensation in vulnerable patients with PWS. A four-year-old boy with genetically confirmed PWS receiving growth hormone therapy

Respiratory Syncytial Virus Infection Triggering a Pulmonary Hypertensive Crisis in a Boy With Prader-Willi Syndrome-Associated Sleep-Disordered Breathing Read More »

Case Report: A pediatric case of chronic active Epstein-Barr virus infection complicated by pulmonary arterial hypertension

Meng Zhang, Kai Wang, Xinyi Xu, Wei Ji, Tingliang Liu, Wei Gao, Ying GuoShanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University.China Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2026; 13: DOI: 10.3389/fcvm.2026.1724841 AbstractObjective: To enhance clinicians’ awareness of pulmonary arterial hypertension (PAH) complicating chronic active Epstein-Barr virus infection (CAEBV) in pediatric patients.Method: Clinical data of a

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