Class 1. Pulmonary Hypertension Associated With Infection

Early venoarterial extracorporeal membrane oxygenation with airway clearance techniques in severe pertussis with pulmonary hypertension in a two-month-old infant: a case report

Yan Liu, Yaoyao Wu, Wei Yue, Xinyan QiuGuangdong Women and Children Hospital. China International Journal of Emergency MedicineInt J Emerg Med 2026; DOI: 10.1186/s12245-026-01247-5 AbstractBackground: Severe pertussis in young infants can lead to respiratory failure, pulmonary hypertension, and sepsis, and remains difficult to manage when conventional therapies fail. In such cases, extracorporeal membrane oxygenation (ECMO) combined with

Early venoarterial extracorporeal membrane oxygenation with airway clearance techniques in severe pertussis with pulmonary hypertension in a two-month-old infant: a case report Read More »

[Association between adverse outcomes during hospitalization and early postnatal weight changes in term appropriate-for-gestational-age infants with early-onset sepsis]

Shi-Cheng Zeng, Xian-Lu Zhou, Ling-Ling Xiang, Zi-Yu HuaChildren’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, and Chongqing Key Laboratory of Pediatric Metabolism and Inflammatory DiseasesChina Chinese Journal of Contemporary PediatricsZhongguo Dang Dai Er Ke Za Zhi 2026; 28:

[Association between adverse outcomes during hospitalization and early postnatal weight changes in term appropriate-for-gestational-age infants with early-onset sepsis] Read More »

Persistent pulmonary hypertension, neonatal stroke, coagulopathy and multi-organ failure due to severe enterovirus sepsis: two case reports

Arangan Kirubakaran, Kirsty Gray, Thomas Slater, Zoe Cass-Tansey, Amna Alvi, Sundar, Sathiyamurthy, Ujwal Kariholumperial College Healthcare NHS Trust. Hillingdon Hospitals NHS Foundation Trust.United Kingdom BioMedical Central PediatricsBMC Pediatr 2026; DOI: 10.1186/s12887-026-06812-8 AbstractBackground: Disseminated neonatal enteroviral infection is a rare and life-threatening condition with significant multi-organ involvement. It often presents with nonspecific symptoms that may be mistakenly

Persistent pulmonary hypertension, neonatal stroke, coagulopathy and multi-organ failure due to severe enterovirus sepsis: two case reports Read More »

Severe Pertussis During Early Infancy from a High-Altitude Region: Two Clinical Cases and Literature Review

Hongju Chen, Sezhen Baima, Xiaoming Xu, Tao Wang, Jing ShiWest China Second University Hospital, Xizang Hospital, Sichuan, Xizang Autonomous Region Women’s and Children’s Hospital and Sichuan University.China Journal of Clinical MedicineJ Clin Med 2026; 15: DOI: 10.3390/jcm15062211 AbstractObjective: To investigate how the high-altitude environment modifies severe pertussis in young infants and analyze its pathophysiological mechanisms and

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Respiratory Syncytial Virus Infection Triggering a Pulmonary Hypertensive Crisis in a Boy With Prader-Willi Syndrome-Associated Sleep-Disordered Breathing

Mari Tsukahara, Hideaki Yagasaki, Koichi Makino, Tomoaki Sano, Takeshi InukaUniversity of Yamanashi.Japan CureusCureus 2026; 18: DOI: 10.7759/cureus.103890 AbstractPrader-Willi syndrome (PWS) is a multisystem genetic disorder frequently complicated by sleep-disordered breathing, including obstructive sleep apnea. Respiratory infections may precipitate acute decompensation in vulnerable patients with PWS. A four-year-old boy with genetically confirmed PWS receiving growth hormone therapy

Respiratory Syncytial Virus Infection Triggering a Pulmonary Hypertensive Crisis in a Boy With Prader-Willi Syndrome-Associated Sleep-Disordered Breathing Read More »

Case Report: A pediatric case of chronic active Epstein-Barr virus infection complicated by pulmonary arterial hypertension

Meng Zhang, Kai Wang, Xinyi Xu, Wei Ji, Tingliang Liu, Wei Gao, Ying GuoShanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University.China Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2026; 13: DOI: 10.3389/fcvm.2026.1724841 AbstractObjective: To enhance clinicians’ awareness of pulmonary arterial hypertension (PAH) complicating chronic active Epstein-Barr virus infection (CAEBV) in pediatric patients.Method: Clinical data of a

Case Report: A pediatric case of chronic active Epstein-Barr virus infection complicated by pulmonary arterial hypertension Read More »

Hypercapnia as a Key Mechanism in the Development of Pulmonary Hypertension in Malignant Pertussis: A Case Report

Juan Ignacio Muñoz-Bonet, Francisco José Sebastián-Cuevas, Eva María Flor-Macián, María del Carmen Ortega-Sánchez, Andrés Rodríguez-Sacristán, Juan BrinesHospital Clínico Universitario. University of Valencia. Hospital Dr. Peset Valencia. Hospital Universitario Virgen Macarena.Spain Respirology Case ReportsRespirol Case Rep 2026; 14: DOI: 10.1002/rcr2.70528 AbstractMalignant pertussis (MP) is a highly lethal complication of pertussis in young infants, typically associated with hyperleukocytosis, pulmonary

Hypercapnia as a Key Mechanism in the Development of Pulmonary Hypertension in Malignant Pertussis: A Case Report Read More »

Endomyocardial calcification with pulmonary and systemic hypertension in a term neonate with multisystem inflammatory syndrome of newborn (MIS-N)

Swasthi Kabi Satpathy. Choudri Muzafar Paswal, Neeraj Gupta, Jai Prakash Soni, Sushil Kumar ChoudharyAll India Institute of Medical Sciences Jodhpur. Dr Sampurnanand Medical College.India British Medical Journal Case ReportsBMJ Case Rep 2026; 19:DOI: 10.1136/bcr-2025-270053 AbstractMultisystem inflammatory syndrome in neonates (MIS-N) is a rare condition linked to perinatal exposure to SARS-CoV-2. We report a case of a

Endomyocardial calcification with pulmonary and systemic hypertension in a term neonate with multisystem inflammatory syndrome of newborn (MIS-N) Read More »

Pulmonary Hypertension Associated With Sickle Cell Disease and Schistosomiasis

Claudia Mickael, Jane C. Kabwe, Dara Fonseca Balladares, Annika S. Bai, Kevin Nolan, Michael H. Lee, Rahul Kumar, Joan F. Hilton, Joseph Phiri, Taonga Musonda, Katie Tuscan, Linda Sanders, Kurt R. Stenmark, Paul W. Buehler, Edford Sinkala, David C. Irwin, Sula Mazimba, Brian B. GrahamUniversity of Colorado Anschutz Medical Campus. National Heart Hospital Lusaka and

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Exchange transfusion for hyperleucocytosis in a critical case of pertussis

Nihil Akcay, Demet Tosun, Ilyas BingölUniversity of Health Sciences, Kanuni Sultan Suleyman Training and Research Hospital.Turkey Paediatrics and International Child HealthPaediatr Int Child Health 2025; DOI: 10.1080/20469047.2025.2595836 AbstractAn 8-week-old infant girl with pertussis-induced respiratory distress, complicated by severe leucocytosis, pulmonary hypertension and respiratory failure is reported. She was treated with mechanical ventilation, exchange transfusion and other

Exchange transfusion for hyperleucocytosis in a critical case of pertussis Read More »

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