Class 3. Pulmonary Hypertension Associated with Alveolar Hypoxia Archives - Page 4 of 6

Altered Smooth Muscle Cell Histone Acetylome by the SPHK2/S1P Axis Promotes Pulmonary Hypertension

A. Dushani C. U. Ranasinghe, Maggie Holohan, Kalyn M. Borger, Deborah L. Donahue, Rafael D. Kuc, Martin Gerig, Andrew Kim, Victoria A. Ploplis, Francis J. Castellino, Margaret A. SchwarzHarper Cancer Research Institute and University of Notre Dame.United States Circulation ResearchCirc Res 2023; 133: 704-719DOI: 10.1161/CIRCRESAHA.123.322740 AbstractBackground: Epigenetic regulation of vascular remodeling in pulmonary hypertension (PH) is poorly […]

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Sleep-Related Hypoxia, Right Ventricular Dysfunction, and Survival in Patients With Group 1 Pulmonary Arterial Hypertension

Megan M. Lowery, Nicholas S. Hill, Lu Wang, Erika B. Rosenzweig, Aparna Bhat, Serpil Erzurum, J. Emanuel Finet, Christine L. Jellis, Sunjeet Kaur, Deborah H. Kwon, Rawan Nawabit, Milena Radeva, Gerald J. Beck, Robert P. Frantz, Paul M. Hassoun, Anna Hemnes, Evelyn M. Horn, Jane A. Leopold, Franz P. Rischard, Reena Mehra, Pulmonary Vascular Disease

Serum Metabolomic Profile in Hypoxia-Induced Pulmonary Hypertension Mice after C75 Treatment

Shun Chen, Shujia Lin, Wei Liu, Qiuping Lin, Yi Yang, Qingzhu Qiu, Yanfang Zong, Tingting Xiao, Cuilan Hou, Lijian XieShanghai Children’s Hospital and Shanghai Jiao Tong University School of Medicine. NHC Key Laboratory of Medical Embryogenesis and Developmental Molecular Biology. JinShan Hospital and Fudan University.China Frontiers in Bioscience Landmark EditionFront Biosci (Landmark Ed) 2023; 28:

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Loss of Prolyl Hydroxylase 1 and 2 in SM22α-Expressing Cells Prevents Hypoxia-Induced Pulmonary Hypertension

Elizabeth A. Barnes, Reiji Ito, Xibing Che, Cristina M. Alvira, David N. CornfieldStanford University.United States and Japan American Journal of Physiology Lung Cellular and Molecular PhysiologyAm J Physiol Lung Cell Mol Physiol 2023; DOI: 10.1152/ajplung.00428.2022 AbstractPulmonary arterial hypertension (PAH) is a disease characterized by increased vasoconstriction and vascular remodeling. Pulmonary artery smooth muscle cells (PASMC) highly

Loss of Prolyl Hydroxylase 1 and 2 in SM22α-Expressing Cells Prevents Hypoxia-Induced Pulmonary Hypertension Read More »

Intrapulmonary arterial contraction assay reveals region-specific deregulation of vasoreactivity to lung injuries

Yan Bai, Guang Li, Laiming Yung, Paul B. Yu, Xingbin AiMassachusetts General Hospital and Harvard Medical School. Brigham and Women’s Hospital. Renmin Hospital and Wuhan University. United States and China American Journal of Physiology Lung Cellular and Molecular PhysiologyAm J Physiol Lung Cell Mol Physiol 2023; 325: L114-L124DOI: 10.1152/ajplung.00293.2022 AbstractIntrapulmonary arteries located in the proximal lung

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SIRT3 Is a Critical Regulator of Mitochondrial Function of Fibroblasts in Pulmonary Hypertension

Min Li, Lydie Plecita-Hlavata, Evgenia Dobrinskikh, B. Alexandre McKeon, Aneta Gandjeva, Suzette Riddle, Aya Laux, Ram Raj Prasad, Sushil Kumar, Rubin M. Tuder, Hui Zhang, Cheng-Jun Hu, Kurt R. StenmarkUniversity of Colorado Denver – Anschutz Medical Campus. Czech Academy of Sciences. United States and Czech Republic American Journal of Respiratory Cell and Molecular BiologyAm J

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PIF1 Promotes Autophagy to Inhibit Chronic Hypoxia Induced Apoptosis of Pulmonary Artery Endothelial Cells

Yujing Zhao, Juan Wu, Shuai Guan, Ting Xue, Xiaolei Wei, Dawei Cao, Pengzhou Kong, Xinri ZhangThe First Hospital of Shanxi Medical University. The First People’s Hospital of Datong.China International Journal of Chronic Obstructive Pulmonary DiseaseInt J Chron Obstruct Pulmon Dis 2023; 18: 1319-1332DOI: 10.2147/COPD.S406453 AbstractPurpose: Pulmonary artery hypertension (PAH) is a common complication of chronic obstructive pulmonary

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Pre-Flight Hypoxemia Challenge Testing in Bronchopulmonary Dysplasia

Jonathan C. Levin, Catherine A. Sheils, Lystra P. HaygenBoston Children’s Hospital and Brigham and Women’s Hospital.United States PediatricsPediatrics 2023; 152DOI: 10.1542/peds.2022-061001 AbstractBackground and objectives: Former premature infants with bronchopulmonary dysplasia (BPD) are at risk for hypoxemia during air travel, but it is unclear until what age. We aimed to determine pass rates for high altitude simulation testing

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Single-cell analysis of peripheral blood from high-altitude pulmonary hypertension patients identifies a distinct monocyte phenotype

Xin-Hua Wu, Yang-Yang He, Zhang-Rong Chen, Ze-Yuan He, Yi Yan, Yangzhige He, Guang-Ming Wang,Yu Dong, Ying Yang, Yi-Min Sun, Yong-Hong Ren, Qiu-Yan Zhao, Xiao-Dan Yang, Li-Ying Wang, Cai-Jun Fu, Miao He, Si-Jin Zhang, Ji-Fen Fu, Hong Liu, Zhi-Cheng JingThe First Affiliated Hospital of Dali University. Henan University. The Affiliated Hospital of Guizhou Medical University. Yulong

Single-cell analysis of peripheral blood from high-altitude pulmonary hypertension patients identifies a distinct monocyte phenotype Read More »