Potential Biomarkers Associated with Pulmonary Vascular Disease

Growth and differentiation factor 15 (GDF15) levels predict adverse respiratory outcomes in premature neonates

Faeq Almudares, Joseph Hagan, Xinpu Chen, Sridevi Devaraj, Bhagavatula Moorthy, Krithika LingappanBaylor College of Medicine. Children’s Hospital of Philadelphia.United States Pediatric PulmonologyPediatr Pulmonol 2023; 58: 271-278DOI: 10.1002/ppul.26197 AbstractGrowth and differentiation factor 15 (GDF15) is a stress-responsive cytokine, and its expression increases during inflammation, hyperoxia, and senescence. Significantly, GDF15 is secreted by the placenta, and maternal levels […]

Growth and differentiation factor 15 (GDF15) levels predict adverse respiratory outcomes in premature neonates Read More »

Endothelin-1 gene polymorphism (G8002A) and endothelial monocyte-activating polypeptide II: Role in vascular dysfunction in pediatric patients with β-thalassemia major

Azza Abdel Gawad Tantawy, Mourad Alfy Ramzy Tadros, Amira Abdel Moneam Adly, Eman Abdel Rahman Ismail, Fatma A. Ibrahim, Nanis Mohammed Salah Eldin, Mahitab Morsy Hussein, Mervat Abdalhameed Alfeky, Sarah Mohammed Ibrahim, Marwa Adel Hashem, Fatma Soliman Elsayed EbeidAin Shams University. Military Medical Services and Military Medical Academy.Egypt CytokineCytokine 2023; 161: DOI: 10.1016/j.cyto.2022.156048 AbstractBackground: Endothelin-1 (ET-1), a potent endogenous vasoconstrictor, stimulates production of reactive oxygen species. Endothelial monocyte-activating polypeptide-II (EMAP-II) is a multifunctional polypeptide.Aim: To assess ET-1 gene polymorphism

Endothelin-1 gene polymorphism (G8002A) and endothelial monocyte-activating polypeptide II: Role in vascular dysfunction in pediatric patients with β-thalassemia major Read More »

Vitamin D Levels and Cardiopulmonary Status in Infants with Acute Bronchiolitis

Ana Estalella-Mendoza, Ana Castellano-Martinez, Jose Carlos Flores-Gonzalez, Lorena Estepapedregosa, Patricia Rodriguez-Campoy, Moises Rodriguez-GonzalezPuerta del Mar University Hospital. Spain Indian PediatricsIndian Pediatr 2022; 59: 384-387DOI: Not Available AbstractBackground: To assess association of Vitamin D deficiency with cardiac and pulmonary status in infants with acute bronchiolitis.Methods: Infants hospitalized with acute bronchiolitis were enrolled and classified as those with serum

Vitamin D Levels and Cardiopulmonary Status in Infants with Acute Bronchiolitis Read More »

Effects of Ponderal Index on Neonatal Mortality and Morbidities in Extremely Premature Infants

Jae Kyoon Hwang, Ha-Na Kang, Ja-Hye Ahn, Hyun Ju Lee, Hyun-Kyung Park, Chang-Ryul KimHanyang University Guri Hospital. Cheongju St. Mary’s Hospital. Hanyang University Seoul Hospital. Republic of Korea Journal of Korean Medical ScienceJ Korean Med Sci 2022; 37: DOI: 10.3346/jkms.2022.37.e198 AbstractBackground: To evaluate how intrauterine stress affects extremely premature infants in terms of intrauterine growth restriction. We

Effects of Ponderal Index on Neonatal Mortality and Morbidities in Extremely Premature Infants Read More »

Postoperative Pulmonary Hemodynamics and Systemic Inflammatory Response in Pediatric Patients Undergoing Surgery for Congenital Heart Defects

Maria Francilene S. Souza, Juliano G. Penha, Nair Y. Maeda, Filomena R. B. G. Galas, Kelly C. O. Abud, Eloisa S. Carvalho, Ana Maria Thomaz, Claudia R. P. Castro, Juliana Pereira, Antonio Augusto LopesUniversity of São Paulo School of Medicine. Brazil Mediators of InflammationMediator Inflamm 2022; DOI: 10.1155/2022/3977585 AbstractThere is scarce information about the relationships between

Postoperative Pulmonary Hemodynamics and Systemic Inflammatory Response in Pediatric Patients Undergoing Surgery for Congenital Heart Defects Read More »

Altered Lung Microbiome and Metabolome Profile in Children With Pulmonary Arterial Hypertension Associated With Congenital Heart Disease

Runwei Ma, Liming Cheng, Yi Song, Yi Sun, Wenting Gui, Yao Deng, Chao Xie, Min LiuFuwai Yunnan Cardiovascular Hospital. Kunming Children’s Hospital. China Frontiers in MedicineFront Med 2022; 9: DOI: 10.3389/fmed.2022.940784 AbstractBackgrounds: Pulmonary arterial hypertension (PAH) is characterized by progressive pulmonary vascular functional and structural changes, resulting in increased pulmonary vascular resistance and eventually right heart failure

Altered Lung Microbiome and Metabolome Profile in Children With Pulmonary Arterial Hypertension Associated With Congenital Heart Disease Read More »

Comparison between BNP and NT-proBNP in pediatric populations

Kwaku D. Tawiah, Caroline E. Franks, Jessica Tang, Avihu Gazit, Dennis J. Dietzen, Christopher W. FarnsworthWashington University School of Medicine. National Institutes of Health.United States Clinical BiochemistryClin Biochem 2022; 109-110: 74-78DOI: 10.1016/j.clinbiochem.2022.08.003 AbstractBackground: B-type natriuretic peptide (BNP) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) are essential biomarkers for the evaluation of cardiac pathologies. However, pediatric reference intervals for

Comparison between BNP and NT-proBNP in pediatric populations Read More »

Hepatoma-derived growth factor is associated with pulmonary vascular remodeling and PAH disease severity and survival

Jun Yang, Anjira S. Ambade, Melanie Nies, Megan Griffiths, Rachel Damico, Dhananjay Vaidya, Stephanie Brandal, Michael W. Pauciulo, Katie A. Lutz, Anna W. Coleman, William C. Nichols, Eric D. Austin, Dunbar Ivy, Paul M. Hassoun, Allen D. EverettJohns Hopkins University. Vagelos College of Physicians and Surgeons Columbia University. University of Cincinnati College of Medicine and

Hepatoma-derived growth factor is associated with pulmonary vascular remodeling and PAH disease severity and survival Read More »

COL18A1 genotypic associations with endostatin levels and clinical features in pulmonary arterial hypertension: a quantitative trait association study

Catherine E. Simpson, Megan Griffiths, Jun Yang, Melanie K. Nies, Dhananjay Vaidya, Stephanie Brandal, Lisa J. Martin, Michael W. Pauciulo, Katie A. Lutz, Anna W. Coleman, Eric D. Austin, D. Dunbar Ivy, William C. Nichols, Allen D. Everett, Paul M. Hassoun, Rachel L. DamicoJohns Hopkins University. Cincinnati Children’s Hospital Medical Center and University of Cincinnati

COL18A1 genotypic associations with endostatin levels and clinical features in pulmonary arterial hypertension: a quantitative trait association study Read More »

Kynurenine metabolites predict survival in pulmonary arterial hypertension: A role for IL-6/IL-6Rα

Zongye Cai, Siyu Tian, Theo Klein, Ly Tu, Laurie W. Geenen, Thomas Koudstaal, Annemien E. van den Bosch, Yolanda B. de Rijke, Irwin K. M. Reiss, Eric Boersma, Claude van der Ley, Martijn Van Faassen, Ido Kema, Dirk J. Duncker, Karin A. Boomars, Karin Tran‑Lundmark, Christophe Guignabert, Daphne MerkusErasmus MC University Medical Center. Zhejiang University

Kynurenine metabolites predict survival in pulmonary arterial hypertension: A role for IL-6/IL-6Rα Read More »

Scroll to Top