Potential Biomarkers Associated with Pulmonary Vascular Disease

Identification of potential serum biomarkers for congenital heart disease children with pulmonary arterial hypertension by metabonomics

Nan Jin, Mengjie Yu, Xiaoyue Du2, Zhiguo Wu, Changlin Zhai, Haihua Pan, Jinping Gu, Baogang XieZhejiang University of Technology. Medical College of Jiaxing University. The Second Affiliated Hospital of Nanchang University. China BioMed Central Cardiovascular DisordersBMC Cardiovasc Dis 2023; 23: DOI: 10.1186/s12872-023-03171-5 AbstractBackground: Pulmonary arterial hypertension is a common complication in patients with congenital heart disease. In […]

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Metabolomic Profiles Differentiate Scleroderma-PAH From Idiopathic PAH and Correspond With Worsened Functional Capacity

Mona Alotaibi, Junzhe Shao, Michael W. Pauciulo, William C. Nichols, Anna R. Hemnes, Atul Malhotra, Nick H. Kim, Jason X-J Yuan, Timothy Fernandes, Kim M. Kerr, Laith Alshawabkeh, Ankit A. Desai, Andreea M. Bujor, Robert Lafyatis, Jeramie D. Waltrous, Tao Long, Susan Cheng, Stephen Y. Chan, Mihit Jain University of California San Diego. Peking University.

Metabolomic Profiles Differentiate Scleroderma-PAH From Idiopathic PAH and Correspond With Worsened Functional Capacity Read More »

Correlation between urinary and serum NT-proBNP in acute bronchiolitis: A pilot study

Moises Rodriquez-Gonzalez, Ana Castellano-Martinez, Ana Estalella-Mendoza, Patricia Rodriguez-Campoy, Lorena Estepa-Pedregosa, Maria Mercedes Calero-Ruiz, Ana Saez-Benito Godino, Jose Carlos Flores-GonzalezPuerta del Mar University Hospital and University of Cádiz. Spain Pediatric PulmonologyPediatr Pulmonol 2023; 58: 492-499DOI: 10.1002/ppul.26215 AbstractBackground and aims: We aimed to analyze the correlation of urinary with serum N-terminal pro-brain natriuretic peptide (NT-proBNP) concentrations and its association

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Long-term Outcome of Children with Newly Diagnosed Pulmonary Arterial Hypertension: Results From the Global TOPP-registry

Mark-Jan Ploegstra, David Dunbar Ivy, Maurice Beghetti, Damien Bonnet, Dursun Alehan, Laszlo Ablonczy, Sandra Mattos, David Bowers, Tilman Humpl, Rolf M. F. Berger,TOPP InvestigatorsMultiple InstitutionsMultiple Countries European Heart Journal of Quality of Care and Clinical OutcomesEur Heart J Qual Care Clin Outcomes 2023; DOI: 10.1093/ehjqcco/qcad020 AbstractBackground and aims: The Tracking Outcomes and Practice in Pediatric Pulmonary Hypertension

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Plasma mid-regional proadrenomedullin level in children with pulmonary hypertension associated with CHD

Shimaa A. Elesawy, Hesham A. El-Serogy, Esraa A. Sorour, Amr M. Zoairar Elsalam General Hospital and Ministry of Health. Tanta University. Egypt Cardiology in the YoungCardiol Young 2023; DOI: 10.1017/S1047951123000471 AbstractAdrenomedullin has been shown to inhibit proliferation in pulmonary artery smooth muscle cells and to alleviate pulmonary artery collagen accumulation in pulmonary hypertension. We aimed to

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Insulin-like growth factor binding Protein-4: A novel indicator of pulmonary arterial hypertension severity and survival

Guillermo Torres, Jun Yang, Megan Griffiths, Stephanie Brandal, Rachel Damico, Dhananjay Vaidya, Catherine E. Simpson, Michael W. Pauciulo, William C. Nichols, David D. Ivy, Eric D. Austin, Paul M. Hassoun, Allen D. EverettJohns Hopkins University. University of Texas Southwestern Medical Center. Cincinnati Children’s Hospital Medical Center. Children’s Hospital Colorado. Vanderbilt University Medical Center.United States Pulmonary

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Relationship between impaired BMP signalling and clinical risk factors at early-stage vascular injury in the preterm infant

Motaharehsadat Heydarian, Prajakta Oak, Xin Zhang, Nona Kamgari, Alida Kindt, Markus Koschlig, Tina Pritzke, Erika Gonzalez- Rodriguez, Kai Förster, Rory E Morty, Friederike Häfner, Christoph Hübener, Andreas W Flemmer, Ali Oender Yildirim, Deepti Sudheendra, Xuefei Tian, Agnese Petrera, Holger Kirsten, Peter Ahnert, Nick Morrell, Tushar J Desai, Jennifer Sucre, Edda Spiekerkoetter, Anne HilgendorffHelmholtz Zentrum München.

Relationship between impaired BMP signalling and clinical risk factors at early-stage vascular injury in the preterm infant Read More »

Growth and differentiation factor 15 (GDF15) levels predict adverse respiratory outcomes in premature neonates

Faeq Almudares, Joseph Hagan, Xinpu Chen, Sridevi Devaraj, Bhagavatula Moorthy, Krithika LingappanBaylor College of Medicine. Children’s Hospital of Philadelphia.United States Pediatric PulmonologyPediatr Pulmonol 2023; 58: 271-278DOI: 10.1002/ppul.26197 AbstractGrowth and differentiation factor 15 (GDF15) is a stress-responsive cytokine, and its expression increases during inflammation, hyperoxia, and senescence. Significantly, GDF15 is secreted by the placenta, and maternal levels

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Endothelin-1 gene polymorphism (G8002A) and endothelial monocyte-activating polypeptide II: Role in vascular dysfunction in pediatric patients with β-thalassemia major

Azza Abdel Gawad Tantawy, Mourad Alfy Ramzy Tadros, Amira Abdel Moneam Adly, Eman Abdel Rahman Ismail, Fatma A. Ibrahim, Nanis Mohammed Salah Eldin, Mahitab Morsy Hussein, Mervat Abdalhameed Alfeky, Sarah Mohammed Ibrahim, Marwa Adel Hashem, Fatma Soliman Elsayed EbeidAin Shams University. Military Medical Services and Military Medical Academy.Egypt CytokineCytokine 2023; 161: DOI: 10.1016/j.cyto.2022.156048 AbstractBackground: Endothelin-1 (ET-1), a potent endogenous vasoconstrictor, stimulates production of reactive oxygen species. Endothelial monocyte-activating polypeptide-II (EMAP-II) is a multifunctional polypeptide.Aim: To assess ET-1 gene polymorphism

Endothelin-1 gene polymorphism (G8002A) and endothelial monocyte-activating polypeptide II: Role in vascular dysfunction in pediatric patients with β-thalassemia major Read More »

Vitamin D Levels and Cardiopulmonary Status in Infants with Acute Bronchiolitis

Ana Estalella-Mendoza, Ana Castellano-Martinez, Jose Carlos Flores-Gonzalez, Lorena Estepapedregosa, Patricia Rodriguez-Campoy, Moises Rodriguez-GonzalezPuerta del Mar University Hospital. Spain Indian PediatricsIndian Pediatr 2022; 59: 384-387DOI: Not Available AbstractBackground: To assess association of Vitamin D deficiency with cardiac and pulmonary status in infants with acute bronchiolitis.Methods: Infants hospitalized with acute bronchiolitis were enrolled and classified as those with serum

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