Pediatric Pulmonary Vascular Disease

Persistent pulmonary hypertension in children after apparent resolution of ultrasound-defined pulmonary hypertension associated with bronchopulmonary dysplasia

Mami Takeoka, Hirofumi Sawada, Yoshihide Mitani, Hiroyuki Ohashi, Noriko Yodoya, Kazunobu Ohya, Naoki Tsuboya, Tomoya Harada, Masahiro HirayamaMie University Graduate School of Medicine. Japan European Journal of PediatricsEur J Pediatr 2024; 184: DOI: 10.1007/s00431-024-05843-6 AbstractTo evaluate pulmonary hemodynamics in patients who had been followed up for bronchopulmonary dysplasia (BPD)-associated pulmonary hypertension (PH) in the mid-term by […]

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Asymmetric right ventricular myocardial work correlates with gold standard measurements of cardiac function in pulmonary hypertension

Simone G. Diab, Ryota Ebata, Dariusz Mroczek, Wei Hui, Espen W. Remme, Thomas Möller, Mark K. FriedbergOslo University Hospital and University of Oslo. Chiba University. Hospital for Sick Children.Norway and Japan Pulmonary CirculationPulm Circ 2024; 14: DOI: 10.1002/pul2.70014 AbstractRight ventricular (RV) (dys)function determines outcomes in pulmonary hypertension (PH). We previously found that asymmetric RV myocardial work

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The Glu86 Residue in TBX4 Proves Critical for Human Lung Development

Przemyslaw Szafranski, Tomasz Gambin, Gail Deutsch, Salma A. Nassef, Mary Clay Dailey, Debra L. Kearney, Pawel StankiewiczBaylor College of Medicine and Texas Children’s Hospital. Warsaw University of Technology. University of Washington School of Medicine. United States and Poland American Journal of Medical Genetics Part AAm J Med Genet A 2024; DOI: 10.1002/ajmg.a.63936 AbstractT-box transcription factors are

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VSD Surgical Closure in Colombia in Children with Secondary Pulmonary Hypertension. Does Altitude Influence Postoperative Pulmonary Pressure?

Linibeth Cruz‑Baquero, Nicolas Molano‑Gonzalez, Daniel García‑Vargas, Alberto García TorresFundación Cardioinfantil-Instituto de Cardiología. Universidad del Rosario. Columbia Pediatric CardiologyPediatr Cardiol 2024; DOI: 10.1007/s00246-024-03697-1 AbstractA retrospective, cross-sectional, descriptive, observational study was carried out to describe the history of pulmonary hypertension in pediatric patients living at different altitudes following surgical correction of ventricular septal defect. Data from 40 patients

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Longitudinal evaluation of hemodynamic blood and echocardiographic biomarkers for the prediction of BPD and BPD-related pulmonary hypertension in very-low-birth-weight preterm infants

Lukas Schroeder, Fabian Ebach, Tamene Melaku, Brigitte Strizek, Jorge Jimenez‑Cruz, Ramona Dolscheid‑Pommerich, Andreas Mueller, Florian KipfmuellerUniversity Children’s Hospital Bonn and University Hospital Bonn.Germany European Journal of PediatricsEur J Pediatr 2024; 184: DOI: 10.1007/s00431-024-05841-8 AbstractVery-low-birth-weight infants (VLBW, < 1500 g) are at risk of developing bronchopulmonary dysplasia (BPD) and are at risk for BPD-related pulmonary hypertension (PH). The longitudinal measurement of innovative blood and echocardiographic

Longitudinal evaluation of hemodynamic blood and echocardiographic biomarkers for the prediction of BPD and BPD-related pulmonary hypertension in very-low-birth-weight preterm infants Read More »

Magnetic resonance imaging of pulmonary hypertension

Christian Johannes KellenbergerUniversity Children’s Hospital Zurich.Switzerland Pediatric RadiologyPediatr Radiol 2024; DOI: 10.1007/s00247-024-06099-w AbstractPulmonary hypertension is a rare but serious disease in children with potentially poor prognosis in the long term. Direct measurement of increased pressure in the pulmonary circulation requires right-heart catheterisation. Echocardiography is the imaging modality commonly used for suggesting the presence of pulmonary hypertension

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Pulmonary manifestations of juvenile vs. adult systemic sclerosis: insights into pathophysiological and clinical features

Gabriele Di Pasquale, Nicholas Caione, Alessio Di Berardino, Giulio Di DonatoUniversity of L’Aquila.Italy Pediatric PulmonologyPediatr Pulmonol 2024; DOI: 10.1002/ppul.27347 AbstractJuvenile systemic sclerosis (jSSc), the pediatric counterpart of systemic sclerosis (SSc), is a rare autoimmune disorder characterized by vasculopathy and fibrotic disorders. It ranks among the rheumatologic diseases with the highest rates of morbidity and mortality, predominantly

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Genetic burden in neonatal and pediatric-onset pulmonary hypertension: A single-center retrospective study using exome sequencing in a Chinese population

Chen Chen Fucheng Li, Hang Zhou, Dan Wang, Fang Fu, Qiuxia Yu, Ruibin Huang, Yan Lu, You Wang, Guilan Chen, Fei Guo, Tingying Lei, Chunlin Ma, Ru LiGuangzhou Women and Children’s Medical Center. Guangzhou Medical University. China Pediatrics and NeonatologyPediatr Neonatol 2024; DOI: 10.1016/j.pedneo.2024.06.010 AbstractObjective: This single-center retrospective study aimed to investigate the genetic factors contributing to

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Interventional Strategies for Children with Progressive Pulmonary Hypertension Despite Optimal Therapy. An Official American Thoracic Society Clinical Practice Guideline

Don Hayes, Jr., Ann L. Jennerich, Ryan D. Coleman, Eric Abston, Gregory T. Adamson, John T. Berger, Sarah P. Cohen, David S. Cooper, Pirooz Eghtesady, Francis Fynn-Thompson, R. Mark Grady, Stephanie M. Hon, Charles W. Hoopes, Teresa Jewell, Hayley Lewthwaite, Michelle F. Liu, David C. McGiffin, Mary P. Mullen, Athar M. Qureshi, David L. S.

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Neurodevelopmental outcome in children between one and five years after persistent pulmonary hypertension of term and near-term newborns

Laetitia Atlan, Lionel Berthomieu, Caroline Karsenty, Géraldine Gascoin, Catherine Arnaud, Sophie BreinigUniversity Hospital and Toulouse III University.France Frontiers in PediatricsFront Pediatr 2024; 12: DOI: 10.3389/fped.2024.1450916 AbstractBackground: Persistent pulmonary hypertension of the newborn (PPHN) is a serious condition that affects 1-2 per 1,000 newborns. Scientific data report the existence of neurological developmental abnormalities between 10 and 30%, but

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