Pediatric Pulmonary Vascular Disease

Viral respiratory infection increases susceptibility of young rats to hypoxia-induced pulmonary edema

Todd C. Carpenter, John T. Reeves, Anthony G. DurmowitzUniversity of Colorado Health Sciences Center.United States Journal of Applied PhysiologyJ Appl Physiol 1998; 84: 1048-1054 DOI: 10.1152/jappl.1998.84.3.1048 AbstractRecent clinical observations of a high incidence of preexisting respiratory infections in pediatric cases of high-altitude pulmonary edema prompted us to ask whether such infections would increase the susceptibility to hypoxia-induced

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Pulmonary edema in 6 children with Down syndrome during travel to moderate altitudes

Anthony G. DurmowiczUniversity of Utah Health Science Center and Primary Children’s Medical Center.United States PediatricsPediatrics 2001; 108: 443-447DOI: 10.1542/peds.108.2.443 AbstractObjective: Children with Down syndrome (DS) are living longer and are increasingly participating in recreational activities. When a child with DS was diagnosed with high-altitude pulmonary edema (HAPE), this study was undertaken to determine whether and under what

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High-altitude pulmonary edema in children with underlying cardiopulmonary disorders and pulmonary hypertension living at altitude

Bibhuti B. Das, Robert R. Wolfe, Kak-Chen Chan, Gary L. Larsen, John T. Reeves, Dunbar IvyChildren’s Hospital, Denver.United States Archives of Pediatric and Adolescent MedicineArch Pediatr Adolesc Med 2004; 158: 1170-1176DOI: 10.1001/archpedi.158.12.1170 AbstractBackground: Pulmonary hypertension has not been described as a predisposing risk factor for high-altitude pulmonary edema (HAPE) in children. Previous studies have shown an association

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Unusual Onset of Hereditary Hemorrhagic Telangiectasia Due to Somatic Mutational Mosaicism: Case Report and Review of the Literature

Virginia Mirra, Margherita Rosa, Cristina Fontanella, Martina Mancuso, Fabio Antonelli, Alice Castaldo, Annalisa Allegorico, Maria Giovanna Russo, Mario Giordano, Alfonsina Tirozzi, Paolo Siani, Daniele De Bras“Santobono-Pausilipon” Children’s Hospital. University of Naples Federico II. AORN Santobono-Pausilipon. University of Campania “Luigi Vanvitelli” and “Ospedali dei Colli”. Italy ChildrenChildren 2025; 12: DOI: 10.3390/children12121701 AbstractHereditary Hemorrhagic Telangiectasia (HHT), also known

Unusual Onset of Hereditary Hemorrhagic Telangiectasia Due to Somatic Mutational Mosaicism: Case Report and Review of the Literature Read More »

Long-Term Outcomes of Transarterial Embolization for Pulmonary Arteriovenous Malformations in Pediatric Hereditary Hemorrhagic Telangiectasia

Alfredo Páez-Carpio, Adeline Y. L. Lim, Alessandro Gasparetto, Michelle Shaw, Felix Ratjen, João G. AmaralHospital for Sick Children and University of Toronto. Canada Cardiovascular and Interventional RadiologyCardiovasc Intervent Radiol 2025; DOI: 10.1007/s00270-025-04322-1 AbstractPurpose: To assess long-term clinical and radiological outcomes of transarterial embolization (TAE) for pulmonary arteriovenous malformations (PAVMs) in children with hereditary hemorrhagic telangiectasia (HHT).Materials and

Long-Term Outcomes of Transarterial Embolization for Pulmonary Arteriovenous Malformations in Pediatric Hereditary Hemorrhagic Telangiectasia Read More »

Pulmonary hemodynamics in children living at high altitudes

Dante Penaloza, Francisco Sime, Luis RuizUniversity Cayetano Heredia.Peru High Altitude Medicine and BiologyHigh Altit Med Biol 2008; 9: 199-207DOI: 10.1089/ham.2008.1004 AbstractThere are numerous publications on altitude-related diseases in adults. In addition, an International Consensus Statement published in 2001 deals with altitude-related illnesses occurring in lowland children who travel to high altitudes. However, despite the millions of

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Right ventricular adaptation in congenital heart disease: Does the type of right ventricular overload matter?

Renee S. Joosen, Gregor J. Krings, Heleen B. van der Zwaan, Nefise Karaman, Marco Guglielmo, Lucas R. Celant, Marco J. W. G€otte, Michael G. Dickinson, Michiel Voskuil, Marielle C. van de Veerdonk, Johannes M. P. J. BreurUniversity Medical Center Utrecht. Amsterdam University Medical Center and University of Amsterdam. Netherlands Journal of Thoracic and Cardiovascular Surgery

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Neonatologist-Performed Echocardiography in Neonatal Pulmonary Hypertension: A Narrative Review of the Literature

Anna Chiara Titolo, Mandy Ferrocino, Eleonora Biagi, Luisa Rizzo, Hajrie Seferi, Valentina Dell’Orto, Serafina Perrone, Susanna EspositoParma University Hospital and University of Parma.Italy DiagnosticsDiagnostics 2025; 15: DOI: 10.3390/diagnostics15243154 AbstractNeonatal pulmonary hypertension (PH) is a major cause of illness and death in newborns. Neonatologist-performed echocardiography (NPE) is increasingly used as a bedside tool to assess heart function,

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Child health and living at high altitude

Susan Niermeyer, P. Andrade Mollinedo, L. HuichoUniversity of Colorado School of Medicine and Children’s Hospital of Colorado. Caja Nacional de Salud and Clínica del Sur and Clínica Alemana. Universidad Nacional Mayor de San Marcos and Universidad Peruana Cayetano Heredia.United States, Bolivia and Peru Archives of Disease in ChildrenArch Dis Child 2009; 94: 806-811DOI: 10.1136/adc.2008.141838 AbstractThe health of

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Clinical manifestations and long-term follow-up in pediatric patients living at altitude with isolated pulmonary artery of ductal origin

Shinichi Takatsuki, Jeffrey Darst, Bibhuti B. Das, Thomas E. Fagan, Robert Wolfe, David Dunbar IvyChildren’s Hospital Colorado and University of Colorado Denver.United States Pediatric CardiologyPediatr Cardiol 2012; 33: 775-781DOI: 10.1007/s00246-012-0213-z AbstractThis study’s aim was to define the clinical manifestations and long-term outcome of pediatric patients living at altitude with isolated pulmonary artery (PA) of ductal origin

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