Pediatric Pulmonary Vascular Disease

Screening Echocardiography Identifies Risk Factors for Pulmonary Hypertension at Discharge in Premature Infants with Bronchopulmonary Dysplasia

B. A. Madden, M. R. Conaway, S. A. Zanelli, M. A. McCullochAnn and Robert H. Lurie Children’s Hospital of Chicago. University of Virginia and University of Virginia Children’s Hospital.United States Pediatric CardiologyPediatr Cardiol 2022; 43: 1743-1751DOI: 10.1007/s00246-022-02911-2 AbstractHypothesis: Premature infants with bronchopulmonary dysplasia (BPD) are at increased risk of secondary pulmonary hypertension (BPD-PH). Prior studies yielded mixed […]

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Neonatal outcome comparisons between preterm infants with or without early pulmonary hypertension following prolonged preterm premature rupture of membranes before 25 gestational weeks in Korean Neonatal Network

Ga Young Park, Won Soon Park, MinSun Kim, Myung Hee Lee, Ga Won Jeon, Sung Shin Kim, Yun Sil ChangSoonchunhyang University Bucheon Hospital and Soonchunhyang University School of Medicine. Samsung Medical Center and Sungkyunkwan University School of Medicine. Inje University Busan Paik Hospital and Inje University College of Medicine.Republic of Korea Journal of Maternal Fetal

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Oxygen Saturation Index in Neonates with a Congenital Diaphragmatic Hernia: A Retrospective Cohort Study

Emily J. J. Horn-Oudshoorn, Marijn J. Vermeulen, Kelly J. Crossley, Suzan C. M. Cochius-den Otter, J. Marco Schnater, Irwin K.M. Reiss, Philip L. J. DeKoninckErasmus MC University Medical Center, Rotterdam. Monash University. Netherlands and Australia NeonatologyNeonatology 2022; 119: 111-118DOI: 10.1159/000520883 AbstractIntroduction: The oxygenation index (OI) is a marker for respiratory disease severity and adverse neonatal outcomes. The

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Pulmonary hypertension screening in children with sickle cell disease

Kok Hoe Chan, Syeda Hiba Rizvi, Wilfredo De Jesus-Rojas, James M. Stark, Ricardo A. Mosquera, Adriana Carolina Prada-Ruiz, Traci Gonzales, Deborah L. Brown, Neethu M. Menon, Trinh T. Nguyen, Cindy K. Jon, Aravind YadavMcGovern Medical School at the University of Texas Health Science Center at Houston. Ponce Health Science University and Ponce Research Institute. Baylor

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A nomogram prediction model for early death in patients with persistent pulmonary hypertension of the newborn

Chuyang Lin, Jiao Mi, Yinyue Zhang†, Sichen Duan, Jinlin Wu, Yifei LiWest China Second University Hospital and Sichuan University.China Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2022; 9: DOI: 10.3389/fcvm.2022.1077339 AbstractBackground: Persistent pulmonary hypertension of the newborn (PPHN) is a major lethal disorder in neonates that leads to an extremely high mortality rate. Thus, the early identification of

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Randomized Clinical and Biochemical Study Comparing the Effect of L-arginine and Sildenafil in Beta Thalassemia Major Children With High Tricuspid Regurgitant Jet Velocity

Eman El-Khateeb, Sahar Mohamed El-Haggar, Osama El-Razaky, Mohamed Ramadan El-Shanshory, Tarek Mohamed Mostafa68904Tanta University.United Kingdom and Egypt Journal of Cardiovascular Pharmacology and TherapeuticsJ Cardiovasc Pharmacol Ther 2022; DOI: 10.1177/10742484221132671 AbstractBackground: Pulmonary hypertension (PHT) is common in β-thalassemia patients due to hemolysis, iron overload and diminished nitric oxide (NO) levels. Biochemical markers can help to understand the pathophysiology and to introduce new therapies for this condition.Aim: This study

Randomized Clinical and Biochemical Study Comparing the Effect of L-arginine and Sildenafil in Beta Thalassemia Major Children With High Tricuspid Regurgitant Jet Velocity Read More »

The association between pulmonary vascular disease and respiratory improvement in infants with type I severe bronchopulmonary dysplasia

Ryan J. Carpenter, Nina Srdanovic, Karen Rychlik, Shawn K. Sen, Nicholas F. M. Porta, Aaron E. Hamvas, Karna Murthy, Amanda L. HauckLurie Children’s Hospital of Chicago and Northwestern University.United States Journal of PerinatologyJ Perinatol 2022; 42: 788-795DOI: 10.1038/s41372-022-01386-6 AbstractObjective: To describe the association between echocardiographic measures of pulmonary vascular disease and time to respiratory improvement among infants

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High altitude simulation testing in patients with congenital diaphragmatic hernia

Ashlyn E. Whitlock, Catherine A. Sheils, Jill M. Zalieckas, Gary Visner, Mary Mullen, Mollie Studley, Lindsay Lemire, Terry L. BuchmillerBoston Children’s Hospital and Harvard Medical School.United States Journal of Pediatric SurgeryJ Pediatr Surg 2022; 57: 195-198DOI: 10.1016/j.jpedsurg.2021.10.044 AbstractAim of study: Congenital Diaphragmatic Hernia (CDH) is associated with lung hypoplasia and pulmonary hypertension. Many patients receive care in

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Chest computed tomography findings of ground-glass nodules with enhancing central vessel/nodule in pediatric patients with BMPR2 mutations and plexogenic arteriopathy

Jason P. Weinman, David A. Mong, LaDonna J. Malone, D. Dunbar Ivy, Robin R. Deterding, Csaba GalambosChildren’s Hospital Colorado.United States Pediatric RadiologyPediatr Radiol 2022; 52: 2549-2556DOI: 10.1007/s00247-022-05413-8 AbstractBackground: Germline mutation in bone morphogenetic protein type II (BMPR2) is the most common cause of idiopathic/heritable pulmonary hypertension in pediatric patients. Despite the discovery of this gene there are

Chest computed tomography findings of ground-glass nodules with enhancing central vessel/nodule in pediatric patients with BMPR2 mutations and plexogenic arteriopathy Read More »

Use of vasopressin in persistent pulmonary hypertension of the newborn: A case series

Swosti Joshi, Vilmaris Quinones Cardona, Ogechukwu R. MenkitiDrexel University College of Medicine and St. Christopher’s Hospital for Children.United States SAGE Medical Case ReportsSAGE Med Cas Rep 2022; DOI: 10.1177/2050313X221102289 AbstractTreatment of neonates with persistent pulmonary hypertension of newborn includes optimization of ventilatory support, use of pulmonary vasodilators, and/or inotropic support. If refractory to this management, some

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