Pediatric Pulmonary Vascular Disease

Pulmonary manifestations of juvenile vs. adult systemic sclerosis: insights into pathophysiological and clinical features

Gabriele Di Pasquale, Nicholas Caione, Alessio Di Berardino, Giulio Di DonatoUniversity of L’Aquila.Italy Pediatric PulmonologyPediatr Pulmonol 2024; DOI: 10.1002/ppul.27347 AbstractJuvenile systemic sclerosis (jSSc), the pediatric counterpart of systemic sclerosis (SSc), is a rare autoimmune disorder characterized by vasculopathy and fibrotic disorders. It ranks among the rheumatologic diseases with the highest rates of morbidity and mortality, predominantly […]

Pulmonary manifestations of juvenile vs. adult systemic sclerosis: insights into pathophysiological and clinical features Read More »

Genetic burden in neonatal and pediatric-onset pulmonary hypertension: A single-center retrospective study using exome sequencing in a Chinese population

Chen Chen Fucheng Li, Hang Zhou, Dan Wang, Fang Fu, Qiuxia Yu, Ruibin Huang, Yan Lu, You Wang, Guilan Chen, Fei Guo, Tingying Lei, Chunlin Ma, Ru LiGuangzhou Women and Children’s Medical Center. Guangzhou Medical University. China Pediatrics and NeonatologyPediatr Neonatol 2024; DOI: 10.1016/j.pedneo.2024.06.010 AbstractObjective: This single-center retrospective study aimed to investigate the genetic factors contributing to

Genetic burden in neonatal and pediatric-onset pulmonary hypertension: A single-center retrospective study using exome sequencing in a Chinese population Read More »

Interventional Strategies for Children with Progressive Pulmonary Hypertension Despite Optimal Therapy. An Official American Thoracic Society Clinical Practice Guideline

Don Hayes, Jr., Ann L. Jennerich, Ryan D. Coleman, Eric Abston, Gregory T. Adamson, John T. Berger, Sarah P. Cohen, David S. Cooper, Pirooz Eghtesady, Francis Fynn-Thompson, R. Mark Grady, Stephanie M. Hon, Charles W. Hoopes, Teresa Jewell, Hayley Lewthwaite, Michelle F. Liu, David C. McGiffin, Mary P. Mullen, Athar M. Qureshi, David L. S.

Interventional Strategies for Children with Progressive Pulmonary Hypertension Despite Optimal Therapy. An Official American Thoracic Society Clinical Practice Guideline Read More »

Neurodevelopmental outcome in children between one and five years after persistent pulmonary hypertension of term and near-term newborns

Laetitia Atlan, Lionel Berthomieu, Caroline Karsenty, Géraldine Gascoin, Catherine Arnaud, Sophie BreinigUniversity Hospital and Toulouse III University.France Frontiers in PediatricsFront Pediatr 2024; 12: DOI: 10.3389/fped.2024.1450916 AbstractBackground: Persistent pulmonary hypertension of the newborn (PPHN) is a serious condition that affects 1-2 per 1,000 newborns. Scientific data report the existence of neurological developmental abnormalities between 10 and 30%, but

Neurodevelopmental outcome in children between one and five years after persistent pulmonary hypertension of term and near-term newborns Read More »

microRNAs in Congenital Diaphragmatic Hernia: Insights into Prenatal and Perinatal Biomarkers and Altered Molecular Pathways: microRNAs in Congenital Diaphragmatic Hernia for Pathway Analysis and Prognostic Biomarkers

James R. Bardill, Anis Karimpour-Fard, Courtney C. Breckenfelder, Carmen C. Sucharov, Caitlin R. Eason, Lauren T. Gallagher, Ludmila Khailova, Clyde J. Wright, Jason Gien, Henry L. Galan, S. Christopher DerderianUniversity of Colorado School of Medicine and Children’s Hospital Colorado. United States American Journal of Obstetrics and Gynecology Maternal and Fetal MedicineAm J Obstet Gynecol MFM

microRNAs in Congenital Diaphragmatic Hernia: Insights into Prenatal and Perinatal Biomarkers and Altered Molecular Pathways: microRNAs in Congenital Diaphragmatic Hernia for Pathway Analysis and Prognostic Biomarkers Read More »

Utility of Serum Matrix Metalloproteinase-7 as a Biomarker in Cholestatic Infants with Congenital Heart Disease

Sindhu Pandurangi, Michael E. Kim, Nicolas Noriega, Bradley Conant, JangDong Seo, Reena Mourya, Pranavkumar Shivakumar, Anna L. Peters, Andrew Misfeldt, Meghan Chlebowski Children’s Medical Center of Dallas and University of Texas Southwestern Medical Center. Hospital for Sick Children. University of Cincinnati College of Medicine and Cincinnati Children’s Hospital Medical Center. United States Pediatric CardiologyPediatr Cardiol

Utility of Serum Matrix Metalloproteinase-7 as a Biomarker in Cholestatic Infants with Congenital Heart Disease Read More »

The molecular consequences of FOXF1 missense mutations associated with alveolar capillary dysplasia with misalignment of pulmonary veins

G. G. Edel, M. van Kempen, A. Boerema‑de Munck, C. N. Huisman, C. A. P. Naalden, R. W. W. Brouwer, S. Koornneef, W. F. J. van IJcken, R. M. H. Wijnen, R. J. RottierErasmus MC-Sophia. Netherlands Journal of Biomedical ScienceJ Biomed Sci 2024; 31: DOI: 10.1186/s12929-024-01088-5 AbstractBackground: Alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV) is

The molecular consequences of FOXF1 missense mutations associated with alveolar capillary dysplasia with misalignment of pulmonary veins Read More »

A bovine model of hypoxia-induced pulmonary hypertension reveals a gradient of immune and matrisome response with a complement signature found in circulation

Jason Williams, Franklyn N. Iheagwam, Sean P. Maroney, Lauren R. Schmitt, R. Dale Brown, Greta M. Krafsur, Maria G. Frid, Maxwell C. McCabe, Aneta Gandjeva, Kurt J. Williams, James P. Luyendyk, . Anthony J. Saviola, Rubin M. Tuder, Kurt Stenmark, Kirk C. HansenUniversity of Colorado Denver and University of Colorado Anschutz Medical Campus. Michigan State

A bovine model of hypoxia-induced pulmonary hypertension reveals a gradient of immune and matrisome response with a complement signature found in circulation Read More »

Principles of resuscitation for infants with severe bronchopulmonary dysplasia

Summer Elshenawy, Monique R. Radman-Harrison, Philip T. Levy, Satyan Lakshminrushimha, Taylor L. Sawyer, Brenda H. LawChildren’s Healthcare of Atlanta and Emory University School of Medicine. Seattle Children’s Hospital and University of Washington School of Medicine. Boston Children’s Hospital and Harvard Medical School. UC Davis Children’s Hospital, UC Davis Health. University of Alberta Faculty of Medicine

Principles of resuscitation for infants with severe bronchopulmonary dysplasia Read More »

Actigraphy Study Endpoints to Reduce Sample Size and Facilitate Drug Development for Pediatric Pulmonary Arterial Hypertension

Haihao Sun, Norman Stockbridge, D. Dunbar Ivy, Jennifer Clark, Angela Bates, Stephanie S. Handler, Usha S. Krishnan, MAry P. Mullen, Delphine Yung, Rachel K. Hopper, Nidhy P. Varghese, Catherine M. Avitabile, Jeff Fineman, Eric D. Austin, Grace FreireU.S. Food and Drug Administration. University of Colorado School of Medicine. Stollery Children’s Hospital and University of Alberta.

Actigraphy Study Endpoints to Reduce Sample Size and Facilitate Drug Development for Pediatric Pulmonary Arterial Hypertension Read More »

Scroll to Top