Pediatric Pulmonary Vascular Disease

Fetal Ductal Constriction, Pulmonary Hypertension and Atrial Septum Mobility: A Correlation Study

Paulo Zielinsky, Polyanna Henriques, Pedro Van Der Sand, Maria Antonia Saldanha, Gabriela Macelaro, Joana NicolosoFundação Universitária de Cardiologia-IC/FUC. Universidade Federal do Rio Grande do Sul-UFRGS.Brazil Journal of Ultrasound in MedicineJ Ultrasound Med 2025; DOI: 10.1002/jum.70130 AbstractObjectives: Fetuses with ductal constriction (FDC), pulmonary hypertension and right ventricular overload after maternal exposure to PGE2 inhibitors-nonsteroidal anti-inflammatory drugs (NSAIDs) or […]

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Transthoracic Echocardiographic Markers of Pulmonary Vein Stenosis Requiring Transcatheter Intervention in Premature Infants

Samantha Holmes, Ernesto Meija, Morgan MacBeth, Jenny Zablah, Benjamin S. FrankUniversity of Colorado School of Medicine. Manning Family Children’s. United States Pediatric CardiologyPediatr Cardiol 2025; DOI: 10.1007/s00246-025-04099-7 AbstractPulmonary vein stenosis (PVS) is a challenging diagnosis, especially in premature infants. Echocardiography is often used as the primary screening tool in this population, but its accuracy in identifying

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Sepsis in the Structurally-Vulnerable Heart: A Case of Infective Endocarditis Masquerading as a Urinary Tract Infection in Pediatric Rheumatic Heart Disease

Anna Mikami, Michael Sherwood, Abrag Nassar, Jennifer Burnham, Miriam Benavides, Samhrutha Sripathi, Chezhiyan MurugesanKern Medical Center.United States CureusCureus 2025; 17: DOI: 10.7759/cureus.94673 AbstractWe present a case of a six-year-old female patient with a history of rheumatic heart disease (RHD), including mitral stenosis, mitral regurgitation, and pulmonary hypertension, who presented with fever, abdominal pain, and urinary findings.

Sepsis in the Structurally-Vulnerable Heart: A Case of Infective Endocarditis Masquerading as a Urinary Tract Infection in Pediatric Rheumatic Heart Disease Read More »

Atrial Flow Regulator: Bridging Pediatric Patients With Pulmonary Arterial Hypertension to Lung Transplantation

Julia Moosmann, Anastasia Schleiger, Felix Berger, Peter KramerDeutsches Herzzentrum der Charité (DHZC), Berlin, Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin. Germany Journal of the American College of Cardiology Case ReportsJACC Case Rep 2025; DOI: 10.1016/j.jaccas.2025.106118 AbstractBackground: Pulmonary arterial hypertension (PAH) in pediatric patients remains challenging, particularly in symptomatic patients with right heart failure despite optimal

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Longitudinal changes of left ventricular hypoplasia and ventricular disproportion in congenital diaphragmatic hernia neonates

Flaminia Pugnaloni, Bartolomeo Bo, Judith Leyens, Irma Capolupo, Andrea Dotta, Pietro Bagolan, Andreas Mueller, Neil Patel, Florian KipfmuellerChildren’s Hospital, University Hospital Bonn and University of Bonn. Bambino Gesù Children’s Hospital-Research Institute, IRCCS. University Medical Center, Mannheim and Heidelberg University. University of Rome “Tor Vergata”. Royal Hospital for Children. Germany, Italy and United Kingdom Journal of

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Early Echocardiographic and Serum Biomarkers Predict Thrombotic Microangiopathy, Endotheliopathy, and Survival after Pediatric Hematopoietic Stem Cell Transplant

Michael A. Smith, Zachary Hutchinson, Elizabeth Colglazier, Claire Parker, Christine S. Higham, Jeffrey R. Fineman, Matt S. Zinter, Christopher C. Dvorak, Hythem M. NawaytouUniversity of California, San Francisco. Transplantation and Cellular TherapyTransplant Cell Ther 2025; DOI: 10.1016/j.jtct.2025.11.024 AbstractBackground: Many life-threatening complications of hematopoietic stem cell transplantation (HSCT) develop secondary to endothelial injury and dysfunction, including transplant-associated thrombotic

Early Echocardiographic and Serum Biomarkers Predict Thrombotic Microangiopathy, Endotheliopathy, and Survival after Pediatric Hematopoietic Stem Cell Transplant Read More »

Efficacy and Tolerability of Selexipag in Pediatric Patients with Pulmonary Arterial Hypertension: An Updated Systematic Review and Meta-analysis

Vasiliki Patsiou, Triantaphyllia Grantza, Thomas Chrysochoidis-Trantas, Maria Kavga, Nikolaos Fragakis, Antonio Ziakas, Alexandra Arvanitaki, George GiannakoulasAHEPA University General Hospital, Hippokrateion General Hospital and Aristotle University of Thessaloniki. Feinstein Institutes for Medical Research. Elmezzi Graduate School of Molecular Medicine and Northwell Health. Royal Brompton Hospital. Greece, United States and United Kingdom Pediatric CardiologyPediatr Cardiol 2025; DOI: 10.1007/s00246-025-04094-y

Efficacy and Tolerability of Selexipag in Pediatric Patients with Pulmonary Arterial Hypertension: An Updated Systematic Review and Meta-analysis Read More »

Early Oxygenation and Mortality in Infants Treated with Inhaled Nitric Oxide (iNO) for Persistent Pulmonary Hypertension of the Newborn (PPHN)

Marina S. Oren, Kikelomo Babata, June Hu, Venkatakrishna Kakkilaya, Patti J. Burchfield, Michelle Hagans, L. Steven Brown, Satyan Lakshminrusimha, Vishal KapadiaUniversity of Texas Southwestern Medical Center. Texas Health Presbyterian Hospital of Dallas. Parkland Health & Hospital System. University of California Davis Children’s Hospital.United States Journal of Pediatrics: Clinical PracticeJ Pediatr Clin Pract 2025; 18: DOI: 10.1016/j.jpedcp.2025.200189

Early Oxygenation and Mortality in Infants Treated with Inhaled Nitric Oxide (iNO) for Persistent Pulmonary Hypertension of the Newborn (PPHN) Read More »

Acute Toxicities and Early Outcomes of Tandem Autologous Stem Cell Transplantation in Pediatric High-Risk Neuroblastoma: A Multicenter Study

Zahra Hudda, Aaron Webster, Eric Anderson, Priscila Badia, Rochelle Bagatell, Saleh Bhar, Alan Bidgoli, Karla Boyd, Sonali Chaudhury, Gabriel Salinas Cisneros, John Craddock, Stella M Davies, Ami V. Desai, Lianna Drobatz, Christopher C. Dvorak, Hannah Elkus, Vanessa A. Fabrizio, Jennifer H Foster, Ellen Fraint, Jason L. Freedman, Jorge Galvez, Mark Garcia, Ann Haight, Christine Higham,

Acute Toxicities and Early Outcomes of Tandem Autologous Stem Cell Transplantation in Pediatric High-Risk Neuroblastoma: A Multicenter Study Read More »

Can N-terminal pro-brain natriuretic peptide accurately diagnose chronic pulmonary hypertension among extremely low gestational age neonates: A Retrospective Cohort Study

Macarena Garcia Gozalo, Amish Jain, Dany E. Weisz, Bonny JasaniLa Paz University Hospital.  Mount Sinai Hospital. University of Toronto. Sunnybrook Health Sciences Centre. Hospital for Sick Children.Spain and Canada Journal of PerinatologyJ Perinatol 2025; DOI: 10.1038/s41372-025-02462-3 AbstractObjective: To evaluate the utility of N-terminal pro-brain natriuretic peptide (NT pro-BNP) for screening and diagnosis of chronic pulmonary hypertension (cPH)

Can N-terminal pro-brain natriuretic peptide accurately diagnose chronic pulmonary hypertension among extremely low gestational age neonates: A Retrospective Cohort Study Read More »

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