Pediatric Pulmonary Vascular Disease

Paediatric pulmonary arterial hypertension following congenital heart defect repair: Enhanced risk stratification and outcomes in a national cohort

Andrew Constantine, Konstantinos Dimopoulos, Robin Condliffe, Paul Clift, Katrijn Jansen, S. John Wort, Grace Chaplin, Kaushiga Krishnathasan, Rami Dhillon, Joydeep Mookerjee, W. Brodie Knight, Caroline B. Jones, Maria N. Velasco Forte, Dirk Wilson, Helen Michael, Alberto Mendoza Soto, Carlos Labrandero, Alejandro Rodríguez Ogando, Antonio Moreno Galdó, Inmaculada Guillén Rodríguez, Lina M. Caicedo Cuenca, Francesca Perin, […]

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Hepatic vein-derived factors may affect pulmonary arteriovenous malformations after single ventricle palliation by modulating vascular cell behavior

Laura Yuriko González-Teshima, Keisuke Hakamada, Kozue Murata, Reiko Nakagawa, Shiro Baba, Yujiro Ide, Maiko Okamura, Akio Ikai, Tadashi Ikeda, Kenji Minatoya, Masaya Hagiwara, Masaya Ikegawa, Hidetoshi MasumotoKyoto University Graduate School of Medicine. RIKEN Center for Biosystems Dynamics Research. Doshisha University. Shizuoka General Hospital. Japan Scientific ReportsSci Rep 2025; 15: DOI: 10.1038/s41598-025-25523-1 AbstractPulmonary arteriovenous malformations (PAVM) are

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Use of SGLT2 (Sodium-Glucose Cotransporter 2) Inhibitors in Pulmonary Hypertension

Benoit Aguado, Grégoire Ruffenach, Thomas Lacoste-Palasset, Agnes Görlach, Marianne Riou, Mathieu Gourmelon, Fabrice Bauer, Marc Humbert, Valerie Schini-Kerth, Jean-Luc Vachiéry, David Montani, Fabrice AntignyUniversité Paris-Saclay and French National Institute for Health and Medical Research. Hôpital Bicêtre and Hôpital Marie Lannelongue. Technical University Munich and German Centre for Cardiovascular Research. Nouvel Hôpital Civil and University Hospital

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Low utility of pre-operative cardiology referrals in adolescent idiopathic scoliosis using a cutoff of Cobb > 70 degrees

Alyssa Barré, Andrew Kirk, Ryan Muchow, Aamir Kadri, Vishwas Talwalkar, Christopher Montgomery, Vincent W. PrusickUniversity of Kentucky. Shriners Hospital for Children – Lexington. United States Spine DeformitySpine Deform 2025; DOI: 10.1007/s43390-025-01243-4 AbstractBackground: Severe adolescent idiopathic scoliosis (AIS) may be associated with cardiopulmonary issues, including previously undiagnosed congenital cardiac anomalies, valvular disease, and pulmonary hypertension. Many centers routinely

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Exchange transfusion for hyperleucocytosis in a critical case of pertussis

Nihil Akcay, Demet Tosun, Ilyas BingölUniversity of Health Sciences, Kanuni Sultan Suleyman Training and Research Hospital.Turkey Paediatrics and International Child HealthPaediatr Int Child Health 2025; DOI: 10.1080/20469047.2025.2595836 AbstractAn 8-week-old infant girl with pertussis-induced respiratory distress, complicated by severe leucocytosis, pulmonary hypertension and respiratory failure is reported. She was treated with mechanical ventilation, exchange transfusion and other

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Investigation of vasoactive intestinal peptide expression and significance in a congenital diaphragmatic hernia animal model

Jiajun Chen, Huijiao Xu, Li Yang, Feifan Chen, Kunpeng Li, Bing Xu, Wenying Liu, Fang HouSichuan Provincial People’s Hospital and University of Electronic Science and Technology of China School of Medicine. China Pediatric Surgery InternationalPediatr Surg Int 2025; 42: DOI: 10.1007/s00383-025-06257-7 AbstractPurpose: To investigate vasoactive intestinal peptide (VIP) expression and distribution in fetal Sprague-Dawley (SD) rat lung

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Causes and risk factors for death in infants with congenital chylothorax

Yuichi Kubo, Satoshi Ibara, Takuya Tokuhisa, Masaya Kibe, Kazuyoshi Sueyoshi, Masato Kamitomo, Motoi KatoShonan Fujisawa Tokushukai Hospital. Kagoshima City Hospital. Imakiire General Hospital. Kagoshima University Hospital.Japan Frontiers in PediatricsFront Pediatr 2025; 13: DOI: 10.3389/fped.2025.1699515 AbstractAim: To identify mortality risk factors in infants with congenital chylothorax (CC) and analyze the causes of death, including pathological examination.Methods: For this single-center

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Early screening for respiratory and cardiac complications in pediatric mucopolysaccharidosis IVA: Insights from a case

Haiyan Shu, Xiaohong Shang, Yan Sun, Guimei Li, Chen Chen, Jianmei YangLicheng District Traditional Chinese Medicine Hospital. Shandong Provincial Hospital Affiliated to Shandong First Medical University. University of Queensland. China and Australia Intractable and Rare Diseases ResearchIntractable Rare Dis Res 2025; 14: 303-305DOI: 10.5582/irdr.2025.01053 AbstractMucopolysaccharidosis type IVA (MPS IVA) is a rare genetic disorder characterized by

Early screening for respiratory and cardiac complications in pediatric mucopolysaccharidosis IVA: Insights from a case Read More »

Inactivation of AXL in Cardiac Fibroblasts Alleviates Right Ventricular Remodeling in Pulmonary Hypertension

Li-Wei Wu, Min Chen, Chen-Yu Jiang, Dai-Ji Jiang, Xu Zhang, Xiao-He Xu, Yi-Wei Liu, Bei Feng, Lin-Cai Ye, Yang-Yang He, Xu Huang, Yi-Chi Zhang, Xing-Liang Zhou, Yi Shen, Tian-Yu Liu, Li-Jun Fu, Yi Yan, Hao ZhangShanghai Children’s Medical Center, National Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Second Affiliated Hospital and

Inactivation of AXL in Cardiac Fibroblasts Alleviates Right Ventricular Remodeling in Pulmonary Hypertension Read More »

Cardiovascular Manifestations and Interventions in Children Living in a Histoplasmosis Endemic Region

Cassandra Campbell, Sandra Arnold, Mario Briceno-Medina, Michael Perez, Shyam SathanandamUniversity of Pittsburgh Medical Center. Le Bonheur Children’s Hospital and University of Tennessee Health Science Center. Dell Children’s Medical Center. Nicklaus Children’s Hospital. United States Pediatric CardiologyPediatr Cardiol 2025; DOI: 10.1007/s00246-025-04123-w AbstractHistoplasmosis in children remains understudied, drawing most clinical understanding from adult populations. Located in a histoplasmosis-hyperendemic

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