Pediatric Pulmonary Vascular Disease or Adult Pulmonary Vascular Disease

Hemodynamic and Clinical Profiles of Pulmonary Arterial Hypertension Patients with GDF2 and BMPR2 Variants

Mei-Tzu Wang, Ken-Pen Weng, Sheng-Kai Chang, Wei-Chun Huang, Lee-Wei ChenNational Yang Ming Chiao Tung University. Kaohsiung Veterans General Hospital. Excelsior Biopharma Inc. Fooyin University. National Sun Yat-Sen University.Taiwan International Journal of Molecular SciencesInt J Mol Sci 2024; 25:DOI: 10.3390/ijms25052734 AbstractAsians have a higher carrier rate of pulmonary arterial hypertension (PAH)-related genetic variants than Caucasians do. This […]

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Fusion imaging for guidance of pulmonary arteriovenous malformation embolisation with minimal radiation and contrast exposure

Catalina Vargas-Acevedo, Ernesto Mejia, Jenny E. Zablah, Gareth J. MorganUniversity of Colorado and Children’s Hospital Colorado.United States Cardiology in the YoungCardiol Young 2024; DOI: 10.1017/S1047951124000349 AbstractHereditary haemorrhagic telangiectasia is an inherited disorder characterised by vascular dysplasia that leads to the development of arteriovenous malformations. Pulmonary arteriovenous malformations occur in approximately 30% of patients with haemorrhagic telangiectasia.

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Mortality in adults with sickle cell disease: Results from the sickle cell disease implementation consortium (SCDIC) registry

Franklin Njoku, Norma Pugh, Donald Brambilla, Barbara Kroner, Nirmish Shah, Marsha Treadwell, Robert Gibson, Lewis L. Hsu, Victor R. Gordeuk, Jeffrey Glassberg, Jane S. Hankins, Abdullah Kutlar, Allison A. King, Julie KanterUniversity of Illinois at Chicago. Research Triangle International. Duke University. University of California San Francisco. Augusta University. Icahn School of Medicine at Mount Sinai.

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Comparison between REVEAL Lite 2 and COMPERA 2.0 for risk stratification in Pulmonary Arterial Hypertension

Sandeep Sahay, Nelson Villasmil Hernandez, Fredrick Wang, Matthew Wooten, Duc T. Nguyen, Charles Fauvel, Raymond Benza, Edward A. GravissHouston Methodist Hospital. Texas A&M School of Medicine. Baylor College of Medicine. Rouen University Hospital. Icahn School of Medicine at Mount Sinai. Houston Medicine Research Institute.United States and France ChestChest 2024;DOI: 10.1016/j.chest.2024.02.052 AbstractBackground: Risk stratification is the cornerstone of

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A Comprehensive Review of Inhaled Nitric Oxide Therapy: Current Trends, Challenges, and Future Directions

Divyanshi Kaplish, Jayant D. Vagha, Revat J. Meshram, Sham LohiyaJawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & ResearchIndia CureusCureus 2024; 16:DOI: 10.7759/cureus.53558 AbstractThis comprehensive review explores the multifaceted landscape of inhaled nitric oxide (iNO) therapy, tracing its historical evolution, mechanisms of action, clinical applications, challenges, and future directions. The nitric oxide signaling pathway,

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RNA m6A methylation and regulatory proteins in pulmonary arterial hypertension

Zhe Wang, Yi-Xuan Zhang, Jun-Zhuo Shi, Yi Yan, Lu-Ling Zhao, Jie-Jian Kou, Yang-Yang He, Xin-Mei Xie, Si-Jin Zhang, Xiao-Bin PangHuaihe Hospital of Henan University. Shanghai Children’s Medical Center, National Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Guangdong Provincial People’s Hospital and Southern Medical University.China Hypertension ResearchHypertens Res 2024; DOI: 10.1038/s41440-024-01607-9 Abstractm6A (N6‑methyladenosine)

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Intentional longitudinal and side-cell stent fractures: Intermediate term follow up

Hitesh Agrawal, Athar M. Qureshi, Henri JustinoTexas Children’s Hospital and Baylor College of Medicine.United States Catheterization and Cardiovascular InterventionsCatheter Cardiovasc Interv 2018; 91: 1110-1118DOI: 10.1002/ccd.27469 AbstractBackground: Use of small diameter stents in young children and jailing of side branches pose significant challenges to future re-interventions. We sought to assess the capacity to induce longitudinal fractures in undersized

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Emerging Epigenetic Targets and Their Molecular Impact on Vascular Remodeling in Pulmonary Hypertension

A. Dushani, C. U. Ranasinghe, T. M. Parinda B. Tennakoon, Margaret A. SchwarzBoston Children’s Hospital and Harvard Medical School. Indiana University School of Medicine.United States CellsCells 2024; 13:DOI: 10.3390/cells13030244 AbstractPulmonary Hypertension (PH) is a terminal disease characterized by severe pulmonary vascular remodeling. Unfortunately, targeted therapy to prevent disease progression is limited. Here, the vascular cell populations

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Outcomes of the Warden Procedure for Partial Anomalous Pulmonary Venous Drainage

Hongyuan Lin, Jun Yan, Qiang Wang, Shoujun Li, Haining Sun, Yajuan Zhang, Liang Zhang, Wenchao LiuFuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College.China Pediatric CardiologyPediatr Cardiol 2020; 41: 134–140DOI: https://doi.org/10.1007/s00246-019-02235-8 AbstractPartial anomalous pulmonary venous drainage (PAPVD) is a common congenital heart disease. If the insertion of an anomalous pulmonary vein (PV)

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Mitochondrial network dynamics in pulmonary disease: Bridging the gap between inflammation, oxidative stress, and bioenergetics

Marissa D. Pokharel, Alejandro Garcia-Flores, David Marciano, Maria C. Franco, Jeffrey R. Fineman, Saurabh Aggarwal, Ting Wang, Stephen M. BlackFlorida International University. University of California, San Francisco.United States Redox BiologyRedox Biol 2024; 70:DOI: 10.1016/j.redox.2024.103049 AbstractOnce thought of in terms of bioenergetics, mitochondria are now widely accepted as both the orchestrator of cellular health and the gatekeeper

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