Pediatric Pulmonary Vascular Disease or Adult Pulmonary Vascular Disease

Inhaled NO at a crossroads in cardiac surgery: current need to improve mechanistic understanding, clinical trial design and scientific evidence

Stefan Muenster, Iratxe Zarragoikoetxea, Andrea Moscatelli, Joan Balcells, Philippe Gaudard, Philippe Pouard, Nandor Marczin, Stefan P. JanssensUniversity Hospital Bonn. Hospital Universitari I Politècnic Fe. IRCCS Istituto Giannina Gaslini. Universitari Vall d’Hebron. University of Montpellier. Assistance Publique-Hopitaux de Paris and Hopital Necker-Enfants Malades. Imperial College. University Hospital Leuven.Germany, Spain, Italy, France, United Kingdom and Belgium Frontiers […]

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Environmental pollutants exposure-derived extracellular vesicles: crucial players in respiratory disorders

Haoran Shen, Rui Zheng, Mulong Du, David C. ChristianiNanjing Medical University. Harvard T.H. Chan School of Public Health. Massachusetts General Hospital.China and United States ThoraxThorax 2024; DOI: 10.1136/thorax-2023-221302 AbstractBackground: Individual exposure to environmental pollutants, as one of the most influential drivers of respiratory disorders, has received considerable attention due to its preventability and controllability. Considering that the

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Causal association of depression, anxiety, cognitive performance, the brain cortical structure with pulmonary arterial hypertension: A Mendelian randomization study

Zeying Zhang, Shelby Kutty, Wei Peng, Gaoming Zeng, Haiyan Luo, Zhenghui Xiao, Qiming Liu, Yunbin XiaoSecond Xiangya Hospital of Central South University. Johns Hopkins School of Medicine. Hunan Children’s Hospital. China Journal of Affective DisordersJ Affect Dis 2024;DOI: 10.1016/j.jad.2024.01.276 AbstractBackground: Patients with pulmonary arterial hypertension (PAH) often present with anxiety, depression and cognitive deterioration. Structural changes in

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Low global arginine bioavailability: a common phenomenon in pulmonary hypertension

Dunia Hatabah, Teresa De Marco, Dana P. McGlothlin, Mary Malloy, Loretta Z. Reyes, Rawan Korman, Gregory J. Kato, Claudia R. MorrisEmory University School of Medicine. University of California, San Francisco. Kaiser Permanente San Francisco. Children’s Healthcare of Atlanta. Blood Science Consulting.United States American Journal of Physiology Lung Cellular and Molecular PhysiologyAm J Physiol Lung Cell

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The Paradox of Pulmonary Vascular Resistance: Restoration of Pulmonary Capillary Recruitment as a Sine Qua Non for True Therapeutic Success in Pulmonary Arterial Hypertension

David Langleben, Stylianos E. Orfanos, Benjamin D. Fox, Nathan Messas, Michele Giovinazzo, John D. CatravasJewish General Hospital and McGill University. Evangelismos Hospital and National and Kapodistrian University of Athens Medical School. Yitzchak Shamir Hospital and Tel Aviv University. Old Dominion University.Canada, Greece, Israel and United States Journal of Clinical MedicineJ Clin Med 2022; 11:DOI: 10.3390/jcm11154568 AbstractExercise-induced

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Viewing Pulmonary Hypertension Through a Pediatric Lens

Stuti Agarwal, Jeffrey Fineman, David N. Cornfield, Cristina M. Alvira, Roham T. Zamanian, Kara Goss, Ke Yuan, Sebastien Bonnet, Olivier Boucherat, Soni Pullamsetti, Miguel A. Alcázar, Elena Goncharova, Tatiana V. Kudryashova, Mark R. Nicolls, Vinicio de Jesús PérezStanford University. University of California, San Francisco. University of Texas Southwestern. Boston Children’s Hospital. University of Laval. Max-Planck-Institute

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Isolated Partial Anomalous Pulmonary Veins: A 10-Year Experience at a Single Center

Can Jin, Yongtao Wu, Zhiyi Wang, Xiaoran Liu, Qiang WangBeijing An Zhen Hospital Affiliated with Capital University of Medical Sciences. China Journal of Surgical ResearchJ Surg Res 2024; 298: 63-70DOI: 10.1016/j.jss.2023.12.022 AbstractIntroduction: Isolated partial anomalous pulmonary venous connection (PAPVC) is difficult to diagnose, and surgical indications remain controversial. We reviewed 10 y of isolated PAPVC cases.Methods: The data

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Digital Spatial Profiling Identifies Distinct Molecular Signatures of Vascular Lesions in Pulmonary Arterial Hypertension

Rubin M. Tuder, Aneta Gandjeva, Sarah Williams, Sushil Kumar, Vitaly O. Kheyfets, Kyle Matthew Hatton-Jones, Jacqueline R. Starr, Jeong Yun, Jason Hong, Nicholas R. West, Kurt R. StenmarkUniversity of Colorado Anschutz Medical Campus School of Medicine. University of Colorado. Griffith University. Brigham and Women’s Hospital and Harvard Medical School. University of California, Los Angeles.United States

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Diagnostic Strategy for Suspected Unilateral Absence of the Pulmonary Artery

Van Luong Hoang, Viet Anh Lam, Thanh Nguyen PhamHanoi National Lung Hospital. Vin University. Hai Phong University of Medicine and Pharmacy.Vietnam Current Medical ImagingCurr Med Imag 2024; DOI: 10.2174/0115734056266404231207071244 AbstractBackground: Unilateral absence of the pulmonary artery (UAPA) is a very rare congenital anomaly.Objective: To analyze the diagnostic strategy applied to seven patients with UAPA who were examined

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Thrombin activatable fibrinolysis inhibitor plasma levels and TAFI Thr325Ile genetic polymorphism in a cohort of Egyptian sickle cell disease patients and impact on disease severity

Mona Hamdy, Iman A. Shaheen, Mohamed Khallaf, Yasmeen M. M. SelimCairo University.Egypt Pediatric Blood and CancerPediatr Blood Cancer 2024; 71:DOI: 10.1002/pbc.30959 AbstractBackground: Thrombin is a critical protease modulating thrombosis as well as inflammation, which are one of the main pathophysiological mechanisms in sickle vasculopathy, and its levels were reported to be high in sickle cell disease (SCD).

Thrombin activatable fibrinolysis inhibitor plasma levels and TAFI Thr325Ile genetic polymorphism in a cohort of Egyptian sickle cell disease patients and impact on disease severity Read More »

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