Pediatric Pulmonary Vascular Disease or Adult Pulmonary Vascular Disease

Inhibition of DLL4/Notch Signaling Pathway Promotes M2 Polarization and Cell Proliferation in Pulmonary Arterial Hypertension

Guangxing Tan, Chenxia Juan, Yan Mao, Gang Xue, Zhuyuan FangJiangsu Province Hospital of Chinese Medicine, Wuxi Hospital of Traditional Chinese Medicine and Affiliated Hospital of Nanjing University of Chinese Medicine. Yangzhou Hospital of Traditional Chinese Medicine. China American Chemical Society OmegaACS Omega 2024; 9: 37923-37933DOI: 10.1021/acsomega.4c04307 AbstractIn this study, we conducted a comprehensive analysis to identify […]

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Long-term outcomes of transcatheter atrial septal defect closure: a single-center retrospective study

Lalita Honghiranrueng, Supaporn Roymanee, Kanjarut Wongwaitaweewong, Jirayut Jarutach, Rujira BuntharikpornpunQueen Sirikit National Institute of Child Health. Prince of Songkla University.Thailand Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2024; 11: DOI: 10.3389/fcvm.2024.1448967 AbstractBackground: Transcatheter atrial septal defect (ASD) closure is the primary approach for treating ASD secundum; however, data on long-term outcomes remain limited. This study aimed to elucidate

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Circulating Endothelin 1 but Not Transforming Growth Factor-β Levels Are Reduced after Pulmonary Endarterectomy in Subjects Affected by Chronic Thromboembolic Pulmonary Hypertension: A Prospective Cohort Study

Pasquale Totaro, Claudio Tirelli, Lucia Sacchi, Annalisa De Silvestri, Mara DeAmici, Fabrizio Grosjean, Giorgia Testa, Alessia Alloni, Eraldo Kushta, Riccardo Albertini, Teresa Rampino, Andrea Maria D’ArminiFoundation I.R.C.C.S. Policlinico San Matteo. University of Milan. University of Pavia. Italy Journal of Clinical MedicineJ Clin Med 2024; DOI: 10.3390/jcm13174977 AbstractBackground and objectives: Endothelin-1 (ET-1) and transforming growth factor-β (TGF-β) play

Circulating Endothelin 1 but Not Transforming Growth Factor-β Levels Are Reduced after Pulmonary Endarterectomy in Subjects Affected by Chronic Thromboembolic Pulmonary Hypertension: A Prospective Cohort Study Read More »

Effect of fasudil on clinical outcomes of pulmonary hypertension: a systematic review and meta-analysis

Wanying Bao, Mengxin Cheng, Xiaoye Chen, Tao Wang, Dan Xu, Hualin Liao, Lei Chen, Fuqiang Wen, Junyun He, Jun ChenWest China Hospital, West China School of Medicine and Sichuan University. West China Second University Hospital. Union Hospital, Tongji Medical College and Huazhong University of Science and Technology. Hospital of Chengdu.China Expert Review of Clinical PharmacologyExp

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Activation of Platelets and the Complement System in Mice with Schistosoma-Induced Pulmonary Hypertension

Claudia Mickael, Mariah Jordan, Janelle N. Posey, Rubin N. Tuder, Eva Nozik, Joshua M. Thurman, Kurt R. Stenmark, Brian B. Graham, Cassidy DelaneyUniversity of Colorado Anschutz Medical Campus. University of California, San Francisco.United States American Journal of Physiology Lung Cellular and Molecular PhysiologyAm J Physiol Lung Cell Mol Physiol 2024; DOI: 10.1152/ajplung.00165.2024 AbstractSchistosomiasis-induced pulmonary hypertension (PH)

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Covid-19-induced pulmonary hypertension in children, and the use of phosphodiesterase-5 inhibitors

Herlina Dimiati Dimas Arya Umara, Iflan NaufalUniversitas Syiah Kuala,Indonesia F1000 ResearchF1000Res 2022; DOI: 10.12688/f1000research.53966.2 AbstractRespiratory tract infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) first occurred in Wuhan, China, in December 2019 and was declared as a pandemic by WHO. The interaction between the 2019 coronavirus disease (COVID-19) and pulmonary hypertension (PH) in children

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Swyer-James-MacLeod Syndrome in a Patient with Eisenmenger Syndrome

Dolunay Gürses, Merve Oğuz, Doğangün Yüksel, Furkan Ufuk, Münevver YılmazPamukkale University Medical School. Turkey Archives of the Turkish Society of CardiologyTurk Kardiyol Dern Ars 2024; 52: 460-463DOI: 10.5543/tkda.2023.59829 AbstractSwyer-James-MacLeod syndrome is characterized radiologically by hyperlucency in a single lung lobe, accompanied by reduced vascularity, alveolar hyperdistention, and air trapping, without bronchial airway obstruction. The most common

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Genetics and precision genomics approaches to pulmonary hypertension

Eric D. Austin, Micheala A. Aldred, Mona Alotaibi, Stefan Gräf, William C. Nichols, Richard C. Trembath, Wendy K. ChungVanderbilt University Medical Center. Indiana University School of Medicine. University of California San Diego. University of Cambridge. Cincinnati Children’s Hospital Medical Center and University of Cincinnati College of Medicine. King’s College London. Boston Children’s Hospital. United States

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Inhaled Nanoparticulate Systems: Composition, Manufacture and Aerosol Delivery

Heidi M. Manour, Priya Muralidharan, Don Hayes Jr.University of Arizona. Ohio State University College of Medicine. United States Journal of Aerosol Medicine and Pulmonary Drug DeliveryJ Aerosol Med Pulm Drug Deliv 2024; 37: 202-218 DOI: 10.1089/jamp.2024.29117.mk AbstractAn increasing growth in nanotechnology is evident from the growing number of products approved in the past decade. Nanotechnology can

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Multiple biomarkers are equivalent to clinical pulmonary arterial hypertension survival risk models

Megan Griffiths, Catherine E. Simpson, Jun Yang, Dhananjay Vaidya, Melanie K. Nies, Stephanie Brandal, Rachel Damico, Paul Hassoun, D. Dunbar Ivy, Eric D. Austin, Michael W. Pauciulo, Katie A. Lutz, Lisa J. Martin, Erika B. Rosenzweig, Raymond L. Benza, William C. Nichols, Cedric Manlhiot, Allen D. EverettJohns Hopkins University. University of Texas Southwestern. Children’s Hospital

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