Pediatric Pulmonary Vascular Disease or Adult Pulmonary Vascular Disease

Myeloid-derived suppressor cells and pulmonary hypertension

Hui Zhang, Qi-Wei Li, Yuan-Yuan Li, Xue Tang, Ling Gu, Han-Min LiuWest China Second University Hospital and Sichuan University. The Fifth People’s Hospital of Chengdu. China Frontiers in ImmunologyFront Immunol 2023; 14: DOI: 10.3389/fimmu.2023.1189195 AbstractPulmonary hypertension (PH) is a chronic pulmonary vascular disorder characterized by an increase in pulmonary vascular resistance and pulmonary arterial pressure. The […]

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Implementation of genomic medicine for rare disease in a tertiary healthcare system: Mayo Clinic Program for Rare and Undiagnosed Diseases (PRaUD)

Filippo Pinto e Vairo, Jennifer L. Kemppainen, Carolyn R. Rohrer Vitek, Denise A. Whalen, Kayla J. Kolbert, Kaitlin J. Sikkink, Sarah A. Kroc, Teresa Kruisselbrink, Gabrielle F. Shupe, Alyssa K. Knudson, Elizabeth M. Burke, Elle C. Loftus, Lorelei A. Bandel, Carri A. Prochnow, Lindsay A. Mulvihill, Brittany Thomas, Dale M. Gable, Courtney B. Graddy, Giovanna

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The perioperative use of inhaled prostacyclins in cardiac surgery: a systematic review and meta-analysis

Berend Marcus, Frederik Marynen, Steffen Fieuws, Dieter Van Beersel, Filip Rega, Steffen RexUniversitair Ziekenhuis Leuven. Katholieke Universiteit Leuven. Belgium Canadian Journal of AnaesthesiaCan J Anaesth 2023; 70: 1381-1393DOI: 10.1007/s12630-023-02520-4 AbstractPurpose: Perioperative pulmonary hypertension (PH) is an independent risk factor for morbidity and mortality in cardiac surgery. While inhaled prostacyclins (iPGI2s) are an established treatment of chronic PH,

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Metabolic reprogramming, oxidative stress, and pulmonary hypertension

Marissa D. Pokharel, David P. Marciano, Panfeng Fu, Maria Clara Franco, Hoshang Unwalla, Kim Tieu, Jeffrey R. Fineman, Ting Wang, Stephen M. BlackFlorida International University.  University of California San Francisco. United States Redox BiologyRedox Biol 2023; DOI: 10.1016/j.redox.2023.102797 AbstractMitochondria are highly dynamic organelles essential for cell metabolism, growth, and function. It is becoming increasingly clear that

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The cascade screening in heritable forms of pulmonary arterial hypertension

Nidhy P. Varghese, Akhilesh A. Padhye, Pilar L. Magoulas, George B. Mallory, Fadel E. Ruiz, Sandeep SahayBaylor College of Medicine Texas Children’s Hospital Houston. Houston Methodist Hospital. Weill Cornell Medical College.United States Pulmonary CirculationPulm Circ 2023;DOI: 10.1002/pul2.12259 AbstractHeritable pulmonary artery hypertension (HPAH) is an increasingly recognized type of pulmonary arterial hypertension, in both pediatric and adult

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Advances in epigenetic modifications of autophagic process in pulmonary hypertension

Min Mao, Shasha Song, Xin Li, Jiayao Lu, Jie Li, Weifang Zhao, Hanmin Liu, Jingxin Liu, Bin ZengWest China Second University Hospital and Sichuan University. School of Life Sciences of Fudan University. Shenzhen Technology University. Shenzhen Reyson Biotechnology Company. North China Pharmaceutical Company. Hebei Huamin Pharmaceutical Company.China Frontiers in ImmunologyFront Immunol 2023; 14:DOI: 10.3389/fimmu.2023.1206406 AbstractPulmonary hypertension

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Evaluation of the diagnostic and prognostic potential of optical coherence tomography (OCT) of the pulmonary arteries during standardised right heart catheterisation in patients with pulmonary hypertension: a cross-sectional single-centre experience

Emilie Zeiger, André Jakob, Robert Dalla Pozza, Markus Fischer, Anja Tengler, Sarah M. Ulrich, Leonie Arnold, Constance G. Weismann, Ingram Schulze-Neick, Nikolaus A. Haas, Joseph PattathuUniversity Hospital and Ludwig-Maximilians-University. Lund University and Skåne University Hospital.Germany and Sweden Cardiovascular Diagnosis and TherapyCardiovasc Diagn Ther 2023; 13: 453-464DOI: 10.21037/cdt-22-421 AbstractBackground: Pulmonary hypertension (PH) is diagnosed based on an invasive

Evaluation of the diagnostic and prognostic potential of optical coherence tomography (OCT) of the pulmonary arteries during standardised right heart catheterisation in patients with pulmonary hypertension: a cross-sectional single-centre experience Read More »

Defining the clinical validity of genes reported to cause pulmonary arterial hypertension

Carrie L. Welch, Micheala A. Aldred, Scrimmitha Balachandar, Dennis Dooijes, Christina A. Eichstaedt, Stefan Graf, Arjan C. Houweling, Rajiv D. Machado, Divya Pandya, Matina Prapa, Memoona Shaukat, Laura Southgate, Jair Tenorio-Castano, ClinGen PH VCEP, Wendy K. Chung, and Multiple Collaborators. International Consortium for Genetic Studies in Pulmonary Hypertension at the Pulmonary Vascular Research InstituteMultiple InstitutionsMultiple

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Retrospective on global pulmonary hypertension clinical trials: 1999-2021

Lu Zheng, Jun Tan, Yi Yan, Shang Wang, Ping Yuan, Cheng Wu, Yin-Tao Zhao, Hai-Bo Yang, Francesco Nappi, Adriano R. Tonelli, Lan Wang, Qing-Hua Hu, Rong JiangFirst Affiliated Hospital of Zhengzhou University. Yeda Hospital of Yantai. Shanghai Children’s Medical Center and National Children’s Medical Center. Shanghai Pulmonary Hospital and Tongji University. Naval Medical University. Centre

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Human liver single nuclear RNA sequencing implicates BMPR2, GDF15, arginine, and estrogen in portopulmonary hypertension

Arun Jose, Jean M. Elwing, Steven M. Kawut, Michael W. Pauciulo, Kenneth E. Sherman, William C. Nichols, Michael B. Fallon, Francis X. McCormackUniversity of Cincinnati College of Medicine and Cincinnati Children’s Hospital Medical Center. Perelman School at the University of Pennsylvania. University of Arizona. United States Communications BiologyCommun Biol 2023; 6DOI: 10.1038/s42003-023-05193-3 AbstractPortopulmonary hypertension (PoPH) is

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