Medical Therapy. Adverse Effects or Lack of Adverse Effects

Management of Pulmonary Vascular Disease Associated with Congenital Left to Right Shunts: A Single Center Experience

Hythem Nawaytou, Ramya Lakkaraju, Leah Stevens, Vadiyala Mohan Reddy, Naveen Swami, Roberta L. Keller, David F. Teitel, Jeffrey R. FinemanUniversity of California,San Francisco.United States Journal of Thoracic and Cardiovascular SurgeryJ Thorac Cardiovasc Surg 2024; DOI: 10.1016/j.jtcvs.2024.05.007 AbstractObjective: To describe the course and outcomes of children under 18 with left-to-right (LR) shunts and pulmonary arterial hypertension (PAH) undergoing […]

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Pulmonary Hypertension and Anastrozole (PHANTOM): A Randomized, Double-Blind, Placebo-Controlled Trial

Steven M. Kawut, Rui Feng, Susan S. Ellenberg, Roham Zamanian, Todd Bull, Murali Chakinala, Stephen C. Mathai, Anna Hemnes, Grace Lin, Margaret Doyle, Ruth Andrew, Margaret MacLean, Ioannis Stasinopoulos, Eric Austin, Angela DeMichele, Haochang Shou, Jasleen Minhas, Nianfu Song, Jude Moutchia, Corey E. VentetuoloUniversity of Pennsylvania Perelman School of Medicine. Stanford University Medical Center. University

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Milrinone in persistent pulmonary hypertension of newborn: a scoping review

Radu Galis, Diane Mudura, Paula Trif, Shivashankar Diggikar, Arun Prasath, Maria Livia Ognean, Jan Mazela, Adrian Lacatusu, Rangasamy Ramanathan, Boris W. Kramer, Yogen SinghEmergency County Hospital Bihor. Poznan University of Medical Sciences. University of Oradea. Oyster Woman and Child Hospital. University of Texas Southwestern. Lucian Blaga University Sibiu. Clinical County Emergency Hospital Sibiu. Emergency County

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Selexipag Dosing Strategies for Pediatric Patients with Pulmonary Arterial Hypertension

Madeline Grossman, Stephen Walker, E. Zachary RamseyChildren’s Hospital of Philadelphia.United States Pediatric CardiologyPediatr Cardiol 2024; DOI: 10.1007/s00246-024-03513-w AbstractThis retrospective chart review of patients less than 18 years old with pulmonary arterial hypertension (PAH) receiving selexipag was conducted to describe selexipag dosing practices, impact on concomitant PAH therapies, and the safety and efficacy of selexipag. Twenty-seven patients

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Effect of prone positioning ventilation on pulmonary function in neonates during venous-arterial extracorporeal membrane oxygenation

Kai-Peng Sun, Si-Jia Zhou, Xiu-Hua Chen, Yi-Rong Zheng, Qiang ChenFujian Children’s Hospital (Fujian Branch of Shanghai Children’s Medical Center) and Fujian Medical University.China Translational PediatricsTransl Pediatr 2024; 13: 575-583DOI: 10.21037/tp-23-485 AbstractBackground: The use of extracorporeal membrane oxygenation (ECMO) technology has significantly decreased mortality rates associated with neonatal pulmonary hypertension and respiratory failure. Prone positioning ventilation (PPV) is

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Cough-induced chylothorax in a two-year-old boy – case report and review of the literature

Melanie Anger, Julian Hofmann, Bettina Ruf, Marc Steinborn, Daniela Reber, Katharina Warncke, Nikolaus RieberKinderklinik München Schwabing, Munich Klinik and School of Medicine and Technical University of Munich. Germany BioMed Central PediatricsBMC Pediatr 2023; 23:DOI: 10.1186/s12887-023-04221-9 AbstractBackground: Chylothorax is a very rare form of pleural effusion in children, especially after the neonatal period, and predominantly occurs secondary to cardiothoracic

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Inhaled NO at a crossroads in cardiac surgery: current need to improve mechanistic understanding, clinical trial design and scientific evidence

Stefan Muenster, Iratxe Zarragoikoetxea, Andrea Moscatelli, Joan Balcells, Philippe Gaudard, Philippe Pouard, Nandor Marczin, Stefan P. JanssensUniversity Hospital Bonn. Hospital Universitari I Politècnic Fe. IRCCS Istituto Giannina Gaslini. Universitari Vall d’Hebron. University of Montpellier. Assistance Publique-Hopitaux de Paris and Hopital Necker-Enfants Malades. Imperial College. University Hospital Leuven.Germany, Spain, Italy, France, United Kingdom and Belgium Frontiers

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Systemic juvenile idiopathic arthritis-associated lung disease: A retrospective cohort study

Konstantin E. Belozerov, Natalia M. Solomatina, Eugenia A. Isupova, Alla A. Kuznetsiva, Mikhail M. KostikSaint-Petersburg State Pediatric Medical University. Children’s City Polyclinic No. 29 of the Kalininsky District of St. Petersburg. Almazov National Medical Research Centre.Russia World Journal of Clinical PediatricsWorld J Clin Pediar 2024; 13:DOI: 10.5409/wjcp.v13.i1.88912 AbstractBackground: Lung damage in systemic juvenile arthritis (sJIA) is one

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Tadalafil in Neonates and Infants With Pulmonary Hypertension Secondary to Bronchopulmonary Dysplasia

Amy Kiskaddon, Tanaka Dang, Daniel MaurielloJohns Hopkins All Children’s Hospital. Johns Hopkins University School of Medicine. Texas Children’s Hospital.United States Journal of Pediatric Pharmacology and TherapeuticsJ Pediatr Pharmacol Ther 2024; 29: 140-143DOI: 10.5863/1551-6776-29.2.140 AbstractObjectives: The primary outcome of this study was to describe the dosing regimen of tadalafil in neonates and infants diagnosed with pulmonary hypertension (PH)

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Occurrence of hyperoxia during iNO treatment for persistent pulmonary hypertension of the newborn: a cohort study

Justine de Jager, Fleur Brouwer, Jeroen Reijman, Roel L. F. van der Palen, Sylke J. Steggerda, Remco Visser, Arjan B. te Pas, Janneke DekkerLeiden University Medical Center.Netherlands European Journal of PediatricsEur J Pediatr 2024;DOI: 10.1007/s00431-024-05506-6 AbstractHigh concentrations of oxygen are often needed to optimize oxygenation in infants with persistent pulmonary hypertension (PPHN), but this can also

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