Review Articles Concerning Pulmonary Vascular Disease

Cardiovascular disease in Sickle cell: mechanisms, diagnostics and therapeutic advances

Elio Haroun, Ankit Agrawal, Aro Daniela Arockiam, Joseph El Dahdah, Joseph Kassab, Michael Nakhla, Michel Chedid El Helou, Harsha Sanaka, Ziad Zalaquett, Simrat Kaur, Tiffany Dong, Rabi Hanna, Brian Griffin, Tom Kai Ming WangCleveland Clinic. United States HeartHeart 2025; DOI: 10.1136/heartjnl-2025-325837 AbstractCardiovascular complications are increasingly recognised as a major driver of morbidity and early mortality in patients […]

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Liver and systemic hemodynamics in cirrhotic children.

Roberto Tambucci, Xavier Stephenne, Aniss Channaoui, Catherine de MagnéeCliniques Universitaires Saint-Luc and UCLouvain. Belgium World Journal of HepatologyWorld J Hepatol 2025; 17: DOI: 10.4254/wjh.v17.i7.103179 AbstractPortal hypertension and cirrhosis are associated with severe hemodynamic changes in hepatic and systemic circulation in the adult population. During cirrhosis progression, circulation becomes hyperdynamic, with cardiac, pulmonary and renal consequences. Cirrhotic

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Systemic Sclerosis: A Key Model of Endothelial Dysfunction

Vincenzo Zaccone, Lorenzo Falsetti, Silvia Contegiacomo, Serena Cataldi, Devis Benfaremo, Gianluca MoronciniMarche Polytechnic University.Italy BiomedicinesBiomedicines 2025; 13: DOI: 10.3390/biomedicines13071771 AbstractSystemic sclerosis (SSc) is a heterogeneous disease characterized by vascular alterations, immune dysregulation, and fibrosis. Solid evidence supports the hypothesis that endothelial dysfunction is the key player in SSc vascular injury and a critical factor concurring to

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Beyond classical collagen: basement membrane collagen IV in age-associated lung diseases

Natalia El-Merhie, Claudia A. Staab-Weijnitz, Janette K. Burgess, Grazyna KwapiszewskaJustus Liebig University. University of Colorado Anschutz Medical Campus. University of Groningen, andUniversity Medical Center Groningen. Medical University of Graz. Germany, United States, Netherlands, Austria European Respiratory ReviewsEur Respir Rev 2025; 34: DOI: 10.1183/16000617.0192-2024 AbstractChronic lung diseases such as COPD, asthma, idiopathic pulmonary fibrosis (IPF) and pulmonary

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Pediatric Pulmonary Arteriovenous Malformations in Patients with Hereditary Hemorrhagic Telangiectasia: Screening, Diagnosis, and Management

Claire S. Kaufman, Minh Anh Nguyen, Amy Bezold, Mark S. ChesnuttOregon Health and Science University. United States Journal of Clinical MedicineJ Clin Med 2025; 14: DOI: 10.3390/jcm14113739 AbstractPulmonary arteriovenous malformations (PAVMs) are abnormal communications between a pulmonary artery and pulmonary vein that bypass the capillary bed, resulting in right-to-left shunting. The majority of PAVMs are associated

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Mitochondrial cardiomyopathies: navigating through different clinical and management pictures between adult and paediatric forms

Rachele Adorisio, Nicoletta Cantarutti, Barbara Siri, Elisa Bellettini, Gessica Ingrasciotta, Erica Mencarelli, Francesca Graziani, Rosa Lillo, Sara Di Marzio, Corrado Di Mambro, Fabrizio Drago, Antonio Amodeo, Diego MartinelliBambino Gesù Children’s Hospital. University of Turin. Fondazione Policlinico Universitario A. Gemelli.Italy Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2025; 12: DOI: 10.3389/fcvm.2025.1621096 AbstractMitochondrial diseases (MD) represent a group of

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Enhancing Drug Development for Paediatric Pulmonary Hypertension-An Integrative Perspective

Steven H. Abman, Sylvia M. Nikkho, Rolf M. F. Berger, Maria Jesus del Cerro, Eric D. Austin, Maurice Beghetti, Dunbar Ivy, Megan Griffiths, Anne Hilgendorff, Steven H. Kawut, Usha S. Krishnan, Mary P. Mullen, Shahin Moledina, Bernard Thébaud, Norman StockbridgeUniversity of Colorado School of Medicine and Children’s Hospital Colorado. Bayer AG. Beatrix Children’s Hospital, University

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Prematurity and obstructive sleep apnea in children: The perfect storm

Oscar Camilo Pantoja-Gomez, Juanita Agudelo-Agudelo, Elida Duenas-Meza, Sonia M. Restrepo-Gualteros, Maria J. Gutierrez, Gustavo NinoUniversidad de La Sabana. Universidad Nacional de Colombia. Johns Hopkins University. Children’s National Hospital and George Washington University School of Medicine and Health Sciences.Columbia and United States Paediatric Respiratory ReviewsPaediatr Respir Rev 2025; DOI: 10.1016/j.prrv.2025.06.001 AbstractAs survival rates for premature infants improve,

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Cardiovascular protective properties of the natural product eugenol

Xin-yu Liu, Yun-ke Nie, Yang Liu, Mei ChenClinical College of Qilu Medical University. China European Journal of PharmacologyEur J Pharmacol 2025;DOI: 10.1016/j.ejphar.2025.177929 AbstractMedicinal herbs have long been used in traditional medicine and their multi-featured bioactivities against the pathophysiology of chronic diseases are currently being extensively investigated in both experimental and clinical settings. Eugenol, a versatile small

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Cardiorespiratory transition in CDH

Deepika Sankaran. Satyan Lakshminrusimha, Michelle J. LimUniversity of California, Davis.United States Seminars in Fetan and Neonatal MedicineSemin Fetal Neonatal Med 2025; DOI: 10.1016/j.siny.2025.101649 AbstractCongenital diaphragmatic hernia (CDH) is a rare congenital anomaly that occurs due to incomplete closure of the diaphragm followed by herniation of abdominal contents into the chest. Fetal hemodynamics are altered in CDH

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