Review Articles Concerning Pulmonary Vascular Disease

Post-translational modification crosstalk in pulmonary arterial hypertension: mechanisms and therapeutic implications

Jialin Liang, Yuxin Xie, Danyan Su, Yusheng Pangirst Affiliated Hospital of Guangxi Medical University. Guangxi University of Chinese Medicine. China Molecular Biology ReportsMol Biol Rep 2026; 53: DOI: 10.1007/s11033-026-12478-3 AbstractPulmonary arterial hypertension (PAH) is a complex vascular disease characterized by endothelial dysfunction, pulmonary arterial smooth muscle cell (PASMC) hyperproliferation, metabolic reprogramming, and immune-inflammatory remodeling. These pathological

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The Role of Piezo Ion Channels in Pulmonary Hypertension

Kewei Chen, Lingchen Li, Yajie Huang, Lixia Ye, Yu Wang, Ziming Zhang, Chengcheng Hang, Qiqi Li, Qianyun Cao, Lizhong DuChildren’s Hospital, Zhejiang University School of Medicine and National Clinical Research Center for Children and Adolescents’ Health and Diseases. Second Affiliated Hospital and School of Medicine of Zhejiang University. China Pulmonary CirculationPulm Circ 2026; 16: DOI: 10.1002/pul2.70360

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Cardiac Remodeling Patterns in Pediatric and Adolescent Patients with Sickle Cell Disease and Their Association with the Genotype and Clinical Severity of the Disease: A Systematic Review

Alam Eldin M. Mustafa, Niemat Mohammed Tahir AliKing Khalid University. University of Kordofan.Saudi Arabia and Sudan HealthcareHealthcare 2026; 14:DOI: 10.3390/healthcare14142180 AbstractBackground: Sickle cell disease (SCD) is the most common inherited blood disorder globally, affecting approximately 300,000 newborns annually. Cardiac remodeling, resulting from chronic anemia, vascular obstruction, and endothelial dysfunction, substantially contributes to morbidity and mortality in patients

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Metabolic reprogramming in pulmonary arterial hypertension

Jun-Zhuo Shi, Jing-Song Ye, Xiao-Rui An, Guo Cheng, Xin Fan, Fang-Fang Meng, Ou Yang, Yang-Han-Yue Zhou, Meng-Jie Zhang, Tian-Yi Yuan, Yi Yan, Yang-Yang HeHuaihe Hospital and Henan University. Shanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Chinese Academy of Medical Sciences and Peking Union Medical College. Pharmacology and TherapeuticsPharmacol Ther 2026;

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Intra- and Peri-Operative Cardiac Arrest in Pediatric Patients: Epidemiology, Risk Factors, Mechanisms, and Management Strategies

Eleni Asimacopou;os, Gloria M. Al Karaki, Kirsten C. OdegardBoston Children’s Hospital.United States Paediatric AnaesthesiaPaediatr Anaesth 2026; DOI: 10.1002/pan.70265 AbstractIntraoperative (IOCA) and perioperative cardiac arrest (POCA) in pediatric patients represents a rare but catastrophic event with significant implications for morbidity and mortality. Despite advances in anesthetic techniques, monitoring technology, and resuscitation protocols, the incidence of IOCA and

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MicroRNA Signatures in Cardiovascular Diseases: A Systematic Literature Review

Hariballav Mahapatra, Pankaj Banotra, Anand Sekar G, Jignesh Sharma, Sharat Vishwanath K, Dinesh TripathiSevayan Diabetes Centre. Sri Jayadeva Institute of Cardiovascular Sciences. Aarupadai Veedu Medical College and Vinayaka Missions Research Foundation. Mansarovar Medical College. Bhopal Memorial Hospital and Research Centre of Bhopal Nursing College. Subharti Medical College.India CureusCureus 2026; 18: DOI: 10.7759/cureus.110938 AbstractCardiovascular diseases remain the

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Hemodynamic phenotyping of bronchopulmonary dysplasia: from transitional circulation to precision cardiopulmonary care

Gabriela S. Trindade, Bianca C. Benincasa, Rita C. Silveira, Renato S. ProcianoyHospital de Clínicas de Porto Alegre and Universidade Federal do Rio Grande do Sul.Brazil Frontiers in PediatricsFront Pediatr 2026; 14: DOI: 10.3389/fped.2026.1877119 AbstractObjectives: Bronchopulmonary dysplasia (BPD) remains one of the most important complications of extreme prematurity and a leading cause of long-term respiratory, cardiovascular, and neurodevelopmental

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JCS/JPCPHS 2025 Guideline on Pulmonary Hypertension and Pulmonary Embolism/Deep Vein Thrombosis

Yuichi Tamura, Kenya Kusunose, Yugo Yamashita, Teiji Akagi, Masanori Atsukawa, Yoshihiro Fukumoto, Ayumi Goda, Shinya Goto, Masaru Hatano, Masataka Ikeda, Keiichi Ishida, Masaharu Kataoka, Masataka Kuwana, Hiromi Matsubara, Makoto Mo, Tetsutaro Nagaoka, Takeshi Ogo, Yoshinori Okada, Seiichiro Sakao, Hirofumi Sawada, Toshiro Shinke, Nobuhiro Tanabe, Norikazu Yamada, Hiroyuki Yamagishi, Shingo Yano, Kohtaro Abe, Shiro Adachi, Kazuya

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Long-Term Complications of Sickle Cell Disease

Luisanna M. Sánchez, Ajibike Lapite, Alicia Chang, Titilope A. FasipeIndiana Hemophilia and Thrombosis Center. Baylor College of Medicine and exas Children’s Hospital. University of Texas at Austin and Dell Children’s Hospital. United States Pediatrics in ReviewPediatr Rev 2026; 47: 394-403DOI: 10.1542/pir.2024-006446 AbstractSCD is a prevalent genetic disorder marked by chronic complications that impact quality of life

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Phenotype-based screening algorithm for chronic pulmonary hypertension in preterm infants with bronchopulmonary dysplasia

Sarah E. Diamond, Amy H. Stanford, Adrianne R. Bischoff, Patrick J. McNamara, Philip T. LevyUniversity of Arkansas for Medical Sciences and Arkansas Children’s Hospital. University of Iowa. Boston Children’s Hospital and Harvard Medical School. United States Journal of PerinatologyJ Perinatol 2026; DOI: 10.1038/s41372-026-02776-w AbstractChronic pulmonary hypertension (cPH) associated with bronchopulmonary dysplasia (BPD) remains a major contributor

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