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Association between hepatic vein Doppler and echocardiographic diastolic indices with invasively measured right ventricular filling pressures in pediatric pulmonary arterial hypertension

Tessa Palmeri, Wei Hui, Charles T. Simpkin, Andreea Dragulescu, Luc Mertens, Dunbar Ivy, Dale Burkett, Mark FriedbergHospital for Sick Children. University of Colorado Medical Campus.Canada and United States International Journal of CardiologyInt J Cardiol 2026; DOI: 10.1016/j.ijcard.2026.134619 AbstractBackground: Increased right ventricular filling pressures (RVFP) are associated with increased mortality risk in children with pulmonary arterial hypertension (PAH). […]

Association between hepatic vein Doppler and echocardiographic diastolic indices with invasively measured right ventricular filling pressures in pediatric pulmonary arterial hypertension Read More »

Non-invasive surrogate of main pulmonary artery stiffness is associated with right ventricular function in experimental pulmonary arterial hypertension

John D. Dauz, Bahram Mirani, J. Paul Santerre, Michelle P. Bendeck, Craig A. Simmons, Mark K. FriedbergHospital for Sick Children and University of Toronto. Ted Rogers Centre for Heart Research. Canada American Journal of Physiology Heart and Circulatory PhysiologyAm J Physiol Heart Circ Physiol 2026; DOI: 10.1152/ajpheart.00459.2026 AbstractMain pulmonary artery (MPA) stiffening increases right ventricular (RV)

Non-invasive surrogate of main pulmonary artery stiffness is associated with right ventricular function in experimental pulmonary arterial hypertension Read More »

The High-Altitude Baby: Neonatal Development and Survival in Hypoxic Environments Neonatal Life in Hypobaric Hypoxia

Amed Soliz, Jorge SolizFlorida International University and Memorial Regional Hospital. Institute Universitaire de Cardiologie et de Pneumologie de Québec (IUCPQ) and Université Laval. Altitude Baby Association. United States and Canada Respiratory Physiology and NeurobiologyRespir Physiol Neurobiol 2026;DOI: 10.1016/j.resp.2026.104609 AbstractHigh altitude exposes the human fetus and newborn to chronic hypobaric hypoxia, markedly reducing oxygen availability during critical

The High-Altitude Baby: Neonatal Development and Survival in Hypoxic Environments Neonatal Life in Hypobaric Hypoxia Read More »

A Biomimetic Miniaturized In Vitro Model to Target Early Markers of Neonatal Pulmonary Vascular Injury

Motaharehsadat Heydarian, Ali Doryab, Juan Henao, Benjamin Schubert, Otmar Schmid, Anne HilgendorffHelmholtz Zentrum München and German Lung Research Center. University of Cambridge. University Hospital Ludwig-Maximilian University. Carl von Ossietzky University.Germany and United Kingdom American Journal of Physiology Lung Cellular and Molecular PhysiologyAm J Physiol Lung Cell Mol Physiol 2026; DOI: 10.1152/ajplung.00002.2026 AbstractPulmonary vascular disease (PVD) is

A Biomimetic Miniaturized In Vitro Model to Target Early Markers of Neonatal Pulmonary Vascular Injury Read More »

Trametinib Therapy for Hypertrophic Cardiomyopathy and Pulmonary Hypertension in a Child With RAF1-Related Noonan Syndrome (p.Ser257Leu): A Case Report

C. Noah Nilsson, Othman A. Aljohani, Michael A. Smith, Rachelle Durand, Inger Norlyk Sheyanth, Hythem Nawaytou, Elliot Stieglitz, Russel Valle, Sanjeev A. DatarUniversity of California San Francisco. Copenhagen University Hospital. United States and Denmark Clinical Case ReportsClin Case Rep 2026; 14:DOI: 10.1002/ccr3.72831 AbstractThis case describes a female infant with RAF1-related Noonan syndrome who developed severe hypertrophic obstructive

Trametinib Therapy for Hypertrophic Cardiomyopathy and Pulmonary Hypertension in a Child With RAF1-Related Noonan Syndrome (p.Ser257Leu): A Case Report Read More »

Unveiling the Link Between COVID-19 and Pulmonary Hypertension

Jad Abdul Khalek, Mohamad Al Hajjar, Zeina Al-Khalil, Jana Salem, Rana Zareef, Fadi Bitar, Mariam ArabiAmerican University of Beirut Medical Center and American University of Beirut.Lebanon Canadian Journal of Infectious Diseases and Medical MicrobiologyCan J Infect Dis Med Microbiol 2026; DOI: 10.1155/cjid/9352258 AbstractIntroduction: The COVID-19 pandemic, caused by the SARS-CoV-2 virus, was first identified in Wuhan, China,

Unveiling the Link Between COVID-19 and Pulmonary Hypertension Read More »

Process Analysis of Neonatal and Pediatric Respiratory Extracorporeal Membrane Oxygenation Referrals: An 8-Year Experience at a High-Volume Center

Anna C. Dermatidis, Tom W. Bayer, Verena Varnholt, Svetlana Hetjens, Felix Dittgen, Alba Perez-Ortiz, Thomas SchaibleUniversity Children’s Hospital Mannheim, Heidelberg University Hospital and University of Heidelberg.Germany Critical care ExplorationsCrit Care Explor 2026; 8: DOI: 10.1097/CCE.0000000000001432 AbstractObjectives: To evaluate neonatal and pediatric extracorporeal membrane oxygenation (ECMO) referrals and transfers to a high-volume center and optimize the process of

Process Analysis of Neonatal and Pediatric Respiratory Extracorporeal Membrane Oxygenation Referrals: An 8-Year Experience at a High-Volume Center Read More »

Reversible Pulmonary Arterial Hypertension Due to Fenfluramine in a Young Child: A Case Report

Uzoma Ndukwe, Adrianne Parkey, Debopam Samanta, Abdelrahman Masri, Erin WillisUniversity of Arkansas for Medical Sciences.United States CureusCureus 2026; 18: DOI: 10.7759/cureus.108354 AbstractFenfluramine is approved for Dravet syndrome and Lennox-Gastaut syndrome (LGS) in children under two years of age and is increasingly used off-label for developmental and epileptic encephalopathies (DEEs). Due to the risk of pulmonary arterial

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Interferon receptor gene dosage differentially regulates hypoxia-induced platelet activation and pulmonary hypertension in Down syndrome

Janelle N. Posey, Mariah Jordan, Amanda Olsen-Dufour, Thi-Tina N. Nguyen, Christine Farrell, Caitlin V. Lewis, Jamie L. Archambault, Christina Sul, Daniel Colon-Hidalgo, Eva S. Nozik, Joaquin M. Espinosa, Kelly D. Sullivan, Cassidy DelaneyUniversity of Colorado Anschutz. United States Frontiers in ImmunologyFront Immunol 2026; DOI: 10.3389/fimmu.2026.1832057 AbstractTrisomy 21 (T21) results in Down syndrome (DS), a condition associated

Interferon receptor gene dosage differentially regulates hypoxia-induced platelet activation and pulmonary hypertension in Down syndrome Read More »

Anomalous origin of the right pulmonary artery from the ascending aorta: a case report and review of the literature

Alwaleed Al-Dairy, Ali Deeb, Zakaria Aldammad, Ahmad Al-BitarDamascus University. Syrian Arab Republic (Syria) International Journal of Surgery Case ReportsInt J Surg Case Rep 2026; 138: 2278-2282DOI: 10.1097/RC9.0000000000000526 AbstractIntroduction: Anomalous aortic origin of a pulmonary artery (AORPA), or hemitruncus arteriosus, is a rare congenital anomaly in which one pulmonary artery arises directly from the ascending aorta. Without timely

Anomalous origin of the right pulmonary artery from the ascending aorta: a case report and review of the literature Read More »

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