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Targeting Lung Heme Iron by Aerosol Hemopexin Administration in Sickle Cell Disease Pulmonary Hypertension

Melissa Lucero, Christina Lisk, Francesca Cendali, Delaney Swindle, Saini Setua, Kiruphagaran Thangaraju, David I. Pak, Quinton O’Boyle, Shuwei Lu, Robert Tolson, Seth Zaeske, Nishant Rana, Saqib Khan, Natalie Westover, Pavel Davizon Castillo, Gemlyn George, Kathryn Hassel, Rachelle Nuss, Nathan Brinkman, Thomas Gentinetta, Andre F. Palmer, Angelo D’Alessandro, Paul W. Buelher, David C. IrwinUniversity of Colorado, […]

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Perioperative extra corporeal membrane oxygenation in neonates with transposition of the great arteries: 15 years of experience

Jesse A. Weeda, Roel L. F. van der Palen, Heleen E. Bunker-Wiersma, Lena Koers, Eelco van Es, Mark G. Hazekamp, Arjan B. te Pas, Peter Paul RoeleveldWillem-Alexander Children’s Hospital and Leiden University Medical Centre. Netherlands European Journal of Cardiothoracic SurgeryEur J Cardiothorac Surg 2025; DOI: 10.1093/ejcts/ezae442 AbstractBackground: Extracorporeal membrane oxygenation (ECMO) can act as a bridge to

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The prediction value of serum anion gap for short-term mortality in pulmonary hypertension patients with sepsis: a retrospective cohort study

Jinhua Zhu, Zeying Zhang, Yefei Lei, Zhenrong Ouyang, Shelby Kutty, Qiming Liu, Yunbin XiaoFirst People’s Hospital of Chenzhou and Hunan Children’s Hospital Affiliated to Jinan University. Xiamen Cardiovascular Hospital of Xiamen University. Johns Hopkins School of Medicine. Second Xiangya Hospital and Affiliated Children’s Hospital of Central South University. China Frontiers in MedicineFront Med 2025; 11: DOI: 10.3389/fmed.2024.1499677 AbstractBackground: The

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The clinical assessment of lung involvement in patients with Still’s disease, results from the multicentre international AIDA Network Still’s Disease Registry

Piero Ruscitti, Antonio Vitale, Ilenia Di Cola, Valeria Caggiano, Pierpaolo Palumbo, Ernesto Di Cesare, Andrea Hinojosa-Azaola, Jiram Torres-Ruiz, Guillermo Arturo, Guaracha-Basañez, Eduardo Martín-Nares, Giuseppe Lopalco, Maria Morrone, Florenzo Iannone, Henrique A. Mayrink Giardini, Rafael Alves Cordeiro, Isabele, Parente de Brito Antonelli, Onorina Berardicurti, Luca Navarini, Francesco Ciccia, Maria Chiara Visconti, Daniela Iacono, Haner Direskeneli, Sukran

The clinical assessment of lung involvement in patients with Still’s disease, results from the multicentre international AIDA Network Still’s Disease Registry Read More »

Novel Therapies for Right Ventricular Failure

Bibhuti B. DasUniversity of Mississippi Medical Center.United States Current Cardiology ReportsCurr Cardiol Rep 2025; 27:DOI: 10.1007/s11886-024-02157-9 AbstractPurpose of review: Traditionally viewed as a passive player in circulation, the right ventricle (RV) has become a pivotal force in hemodynamics. RV failure (RVF) is a recognized complication of primary cardiac and pulmonary vascular disorders and is associated with a

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[Prognosis of bronchopulmonary dysplasia]

Ying-Zhen Zhou, Ting Wang, Xing-Meng Fu, Bing-Ming Peng, Zhou FuChildren’s Hospital of Chongqing Medical University and National Clinical Research Center for Child Health and Disorders.China Chinese Journal of Contemporary PediatricsZhongguo Dang Dai Er Ke Za Zhi 2025; 27: 115-120DOI: 10.7499/j.issn.1008-8830.2406004 AbstractChildren with bronchopulmonary dysplasia (BPD) often exhibit severe respiratory problems and significant pulmonary dysfunction during school

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Endogenous hydrogen sulfide persulfidates endothelin type A receptor to inhibit pulmonary arterial smooth muscle cell proliferation

Yanan Zhang, Xiaoyu Tiana, Liangyi Chenb, Shiqun Zhaob, Xinjing Tang, Xin Liu, Dan Zhou, Chaoshu Tang, Bin Geng, Junbao Dua, Hongfang Jina, Yaqian HuangPeking University First Hospital and Peking University. Wuhan Children’s Hospital. Fuwai Hospital and Peking Union Medical College. China Redox BiologyRedox Biol 2025; 80: DOI: 10.1016/j.redox.2025.103493 AbstractBackground: The binding of endothelin-1 (ET-1) to endothelin type

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Mortality Patterns in Pediatric Pulmonary Vein Stenosis: Insights Into Right Ventricular Systolic Pressure Associations

Daiji Takajo, Paul J. Critser, Michelle Cash, Melissa Magness, Russel HirschCincinnati Children’s Hospital Medical Center and University of Cincinnati.United States Journal of the American Heart AssociationJ Am Heart Assoc 2025; DOI: 10.1161/JAHA.124.037908DOI: 10.1161/JAHA.124.035037 (correction) AbstractBackground: Pulmonary vein stenosis in children is associated with a poor prognosis. However, the cause and risk factors for mortality remain uncertain.Methods: This retrospective, single-center

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Amniotic fluid stem cell extracellular vesicles as a novel fetal therapy for pulmonary hypoplasia: a review on mechanisms and translational potential

Fabian Doktor, Lina Antounians, Rebeca Lopes Figueira, Kasra Khalaj, Miriam Duci, Augusto ZaniHospital for Sick Children and University of Toronto. Leipzig University.Canada and Germany Stem Cells Translational MedicineStem Cells Transl Med 2025; 14: DOI: 10.1093/stcltm/szae095 AbstractDisruption of developmental processes affecting the fetal lung leads to pulmonary hypoplasia. Pulmonary hypoplasia results from several conditions including congenital diaphragmatic

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Postnatal management of preterm infants with congenital diaphragmatic hernia

Emma Williams, Stephanie Lau, Nimrah Abbasi, Eveline Lapidus-Krol, Priscilla P. L. Chiu, Brian T. KalishHospital for Sick Children and University of Toronto. Mount Sinai Hospital. Canada Pediatric Surgery InternationalPediatr Surg Int 2025; 41: DOI: 10.1007/s00383-025-05964-5 AbstractIntroduction: Congenital diaphragmatic hernia (CDH) in the preterm population is increasingly common in the current era of fetal endoluminal tracheal occlusion (FETO)

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