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Pharmacological Treatment Practices for Patients with Congenital Heart Disease and Pulmonary Hypertension in Japan: Insights from the Japanese Association of Congenital Heart Disease Registry (JACPHR)

Taku Ishii, Keiko Uchida, Susumu Hosokawa, Reina Ishizaki, Naofumi F. Sumitomo, Yoshiyuki Furutani, Hidekazu Ishida, Shinichi Takatsuki, Kei Inai, Kunihiko Takahashi, Shigetoyo Kogaki, Hiroyuki Fukushima, Yuichi Tamura, Hiroyuki Yamagishi, Shozaburo Doi, Japanese Association of Congenital Heart Disease Registry (JACHDR) membersInstitute of Science Tokyo. Keio University School of Medicine, Tokyo Medical University. Japanese Red Cross Mushashino […]

Pharmacological Treatment Practices for Patients with Congenital Heart Disease and Pulmonary Hypertension in Japan: Insights from the Japanese Association of Congenital Heart Disease Registry (JACPHR) Read More »

Shone’s Syndrome and Transplant: A Road Less Traveled

Lyana Labrada, Tripti Gupta, Christiane Haeffele, Adam D. DeVore, Jonathan MenachemTemple University Hospital. University of San Diego. Stanford University. Duke University School of Medicine. Vanderbilt University Medical Center.United States Journal of the American College of Cardiology Case ReportsJACC Case Rep 2025; DOI: 10.1016/j.jaccas.2025.105000 Abstract“Shone’s syndrome” was identified in 1963 as a constellation of 4 coexisting lesions

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Inpatient outcomes among children with Down syndrome: a Kids’ Inpatient Database study

Po-Yang Tsou, Yu-Hsun Wang, Ignacio E. TapiaBoston Children’s Hospital and Harvard Medical School. Tufts Medical Center. University of Miami Health System.United States BioMedical Central PediatricsBMC Pediatr 2025; 25: DOI: 10.1186/s12887-025-05899-9 AbstractBackground: Children with Down Syndrome (DS) are more likely to have multi-system comorbidities leading to more frequent hospitalizations than the general population. We aim to evaluate whether

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p53 maintains lineage fidelity during lung capillary injury-repair in neonatal hyperoxia

Lisandra Vila Ellis, Jonathan D. Bywaters, Amanda Ceas, Yun Liu, Jennifer M. S. Sucre, Jichao ChenNorthwestern University.  Vanderbilt University Medical Center. Cincinnati Children’s Hospital Medical Center.United States Journal of Clinical Investigation InsightsJCI Insights 2025;DOI: 10.1172/jci.insight.182880 AbstractBronchopulmonary dysplasia (BPD), a prevalent and chronic lung disease affecting premature newborns, results in vascular rarefaction and alveolar simplification. Although the

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Hereditary hemorrhagic telangiectasia in pediatrics: descriptive study in a specialized unit

Magalí Squitín Tasende, Nicolás Guerrero Serravalle, Lucía G. Pérez, Ana Braslavsky, Marcelo SerraHospital Italiano de Buenos Aires and Universidad Hospital Italiano.Argentina Archivos Argentinos de PediatríaArch Argent Pediatr 2025; DOI: 10.5546/aap.2025-10661.eng AbstractIntroduction. Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular dysplasia characterized by bleeding telangiectasias and arteriovenous malformations (AVMs) in the brain, lungs, liver, and gastrointestinal

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Neighborhood Child Opportunity Index and Outcomes in Pediatric Pulmonary Hypertension

Jai Krishan Khurana, Stuart Lipsitz, Diana L. Geisser, Katie M. Moynihan, Mary P. MullenBoston Children’s Hospital, Brigham and Women’s Hospital and Harvard Medical School.United States Pediatric CardiologyPediatr Cardiol 2025; DOI: 10.1007/s00246-025-03981-8 AbstractThe role of social determinants of health (SDoH) in pediatric pulmonary hypertension (PH) outcomes are inadequately characterized. We hypothesized outcomes differ according to SDoH with

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Transcatheter Versus Surgical Correction of Superior Sinus Venosus Defects: Comparison of the Outcomes and Late Complications

Puthiyedath Thejaswi, Kothandam Sivakumar, Farheen Qureshi, Pramod Sagar. Sreeja Pavithran, Ravi AgarwalMadras Medical Mission.India Pediatric CardiologyPediatr Cardiol 2025; DOI: 10.1007/s00246-025-03975-6 AbstractTranscatheter correction (TC) of sinus venosus defects (SVD) is an emerging alternative to surgical correction (SC). Superior vena caval (SVC) or right upper pulmonary vein (RUPV) stenosis and sick sinus syndrome are complications of SC. This

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Severe pertussis complicated by pulmonary hypertension in a Moroccan infant: a case report

Mehdi Belhakim, Zineb El jaouhahri, Aicha Boudar, Loubna Benaddi, Karima Naanani, Rachida Habbal, Abdelaziz ChlilekUniversity Hospital Ibn Rochd, Children’s Hospital and University Hassan II.Morocco Journal of Medical Case ReportsJ Med Case Rep 2025; 19: DOI: 10.1186/s13256-024-04898-1 AbstractBackground: Despite high vaccination coverage among children, pertussis continues to pose a significant public health challenge in Morocco. Mortality primarily affects

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Liver and systemic hemodynamics in cirrhotic children.

Roberto Tambucci, Xavier Stephenne, Aniss Channaoui, Catherine de MagnéeCliniques Universitaires Saint-Luc and UCLouvain. Belgium World Journal of HepatologyWorld J Hepatol 2025; 17: DOI: 10.4254/wjh.v17.i7.103179 AbstractPortal hypertension and cirrhosis are associated with severe hemodynamic changes in hepatic and systemic circulation in the adult population. During cirrhosis progression, circulation becomes hyperdynamic, with cardiac, pulmonary and renal consequences. Cirrhotic

Liver and systemic hemodynamics in cirrhotic children. Read More »

Cardiac function in children with congenital diaphragmatic hernia: cardiac strain at birth and at 2-5 weeks of age

Katarina Övermo Tydén, Kerstin Magnusson, Carmen Mesas Burgos, Baldvin Jonsson, Felicia NordenstamKarolinska Institutet and Karolinska University Hospital.Sweden Frontiers in PediatricsFront Pediatr 2025; 13: DOI: 10.3389/fped.2025.1598695 AbstractIntroduction: Neonates with congenital diaphragmatic hernia (CDH) often present with pulmonary hypertension and various forms of cardiac dysfunction, affecting right or left ventricle or both. Although pulmonary hypertension typically improves over time,

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