Fresh (PHresh). Less than 1-2 years since publication

High Shear Stress Reduces ERG Causing Endothelial-Mesenchymal Transition and Pulmonary Arterial Hypertension

Tsutomo Shinohara, Jan-Ranier Moonen, Yoon Hong Chun, Yannick C. Lee-Yow, Kenichi Okamura, Jason M. Szafron, Jordan Kaplan, Aiqin Cao, Lingli Wang, Divya Guntur, Shalina Taylor, Sarasa Isobe, Melody Dong, Weiguang Yang, Katherine Guo, Benjamin D. Franco, Cholawat Pacharinsak, Laura J. Pisani, Shinji Saitoh, Yoshihide Mitani, Alison L. Marsden, Jesse M. Engreitz, Jakob Körbelin, Marlene RabinovitchLucile […]

High Shear Stress Reduces ERG Causing Endothelial-Mesenchymal Transition and Pulmonary Arterial Hypertension Read More »

Fetal-to-Neonatal Transition of an Infant with Transposition of the Great Arteries and Intact Ventricular Septum: A Case Report

Jesse A. Weeda, Arjan B. te Pas, Monique C. Haak, Nico A.Blom, Roel L.F. van der PalenWillem-Alexander Children’s Hospital and Leiden University Medical Centre. Netherlands Biomedicine HubBiomed Hub 2024;DOI: 10.1159/000542723 AbstractIntroduction: Transposition of the great arteries (TGA), especially with intact ventricular septum (TGA-IVS), presents unique challenges during fetal-to-neonatal transition, which can contribute to developing persistent pulmonary hypertension

Fetal-to-Neonatal Transition of an Infant with Transposition of the Great Arteries and Intact Ventricular Septum: A Case Report Read More »

Quantification of lung perfusion by a novel echocardiographic approach in pediatric pulmonary vein stenosis

Joseph M. Stidham, Sarah LaBarge, Jennifer H. Huang, Lars Grosse-Wortmann, Patrick D. EversOregon Health and Sciences University.United States Journal of the American Society of EchocardiographyJ Am Soc Echocardiogr 2024; DOI: 10.1016/j.echo.2024.11.016 AbstractAbstract Not Available CategorySegmental Pulmonary Venous Disease. Without a Focus on Pulmonary HypertensionDiagnostic Testing for Pulmonary Vascular Disease. Non-invasive Testing Age Focus: Pediatric Pulmonary Vascular

Quantification of lung perfusion by a novel echocardiographic approach in pediatric pulmonary vein stenosis Read More »

Innovative Dual Combination Cospray-Dried Rock Inhibitor/l-Carnitine Inhalable Dry Powder Aerosols

Maria F. Acosta, David Encinas-Basurto, Michael D. Abrahamson, Basanth Babu Eedara, Don Hayes, Jr., Jeffrey R. Fineman, Stephen M. Black, Heidi M. MansourUniversity of Arizona College of Pharmacy. Universidad de Sonora. Florida International University. Ohio State University College of Medicine. Cincinnati Children’s Medical Center. University of California San Francisco School of Medicine. United States and

Innovative Dual Combination Cospray-Dried Rock Inhibitor/l-Carnitine Inhalable Dry Powder Aerosols Read More »

Update on Eisenmenger syndrome – Review of pathophysiology and recent progress in risk assessment and management

Ranjan Banerjee, Alexander R. OpotowskyCincinnati Children’s Hospital and University of Cincinnati College of MedicineUnited States International Journal of Cardiology Congenital Heart DiseaseInt J Cardiol Congenit Heart Dis 2024; DOI: 10.1016/j.ijcchd.2024.100520 AbstractLongstanding left-to-right shunting associated with congenital heart disease (CHD) can ultimately lead to pulmonary vascular remodeling, pulmonary arterial hypertension, and shunt reversal, the hallmark feature of

Update on Eisenmenger syndrome – Review of pathophysiology and recent progress in risk assessment and management Read More »

LPS Increases Artery but Not Airway Contraction in Precision Cut Lung Slices from a Mouse Model of ARDS

Emma Lamanna, Zoe F. Kropf, Raymond Luong, Matthew Narayan, Elizabeth A. Richards, Bailey Cardwell, Simon G. Royce, Claudia A. Nold-Petry, Jane E. BourkeMonash University. RMIT University. Royal Melbourne Institute of Technology. Hudson Institute of Medical Research.Australia American Journal of Respiratory Cell and Molecular BiologyAm J Respir Cell Mol Biol 2024; DOI: 10.1165/rcmb.2024-0249OC AbstractAcute respiratory distress syndrome

LPS Increases Artery but Not Airway Contraction in Precision Cut Lung Slices from a Mouse Model of ARDS Read More »

Congenital heart disease and arrhythmia disorders in newborns with congenital diaphragmatic hernia: a 23-year experience at a UK university pediatric surgical centre

Wan Teng Lee, Chun Sui Kwok, Paul D. LostyUniversity of Liverpool and Alder Hey Children’s Hospital. Ramathibodi Hospital.United Kingdom and Thailand Pediatric Surgery InternationalPediatr Surg Int 2024; DOI: 10.1007/s00383-024-05927-2 AbstractPurpose: Congenital diaphragmatic hernia (CDH) is associated with congenital heart disease (CHD) and index newborns reportedly may experience cardiac arrhythmia disorders [Tella et al.-Pediatric Critical Care Medicine 2022].

Congenital heart disease and arrhythmia disorders in newborns with congenital diaphragmatic hernia: a 23-year experience at a UK university pediatric surgical centre Read More »

Management of Neonatal Hyperinsulinemic Hypoglycemia: Trends Over Nine Years

Sabitha Sasidharan Pillai, Meghan E. Fredette, Joshua Ray Tanzer, Lisa Swartz ToporHasbro Children’s Hospital and Warren Alpert Medical School of Brown University.United States Rhode Island Medical JournalR I Med J 2024; 108: 23-29DOI: Not Available. chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/http://www.rimed.org/rimedicaljournal/2025/01/2025-01-23-contribution-pillai.pdf AbstractBackground: With increasing use of diazoxide for hyperinsulinemic hypoglycemia (HH), reporting of serious side effects of diazoxide such as pulmonary

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Resolution of Fenfluramine-associated pulmonary arterial hypertension in Lennox-Gastaut syndrome: A case report and literature review

Rebecca Strafella, Richard Wang, Marissa Petchpradub, Ariel Sacknovitz, Patricia E. McGoldrick, Steven M. WolfNew York Medical College and Westchester Medical Center. Boston Children’s Health.United States Epilepsy and Behavior ReportsEpilepsy Behav Rep 2024; 28: DOI: 10.1016/j.ebr.2024.100730 AbstractFenfluramine is a medication originally approved for weight loss before being withdrawn for an association with the development of pulmonary arterial

Resolution of Fenfluramine-associated pulmonary arterial hypertension in Lennox-Gastaut syndrome: A case report and literature review Read More »

Use of Right Ventricular Free-Wall Strain in a Multivariable Estimate of Right Ventricular-Arterial Coupling in Pediatric Pulmonary Arterial Hypertension

Charles T. Simpkin, D. Dunbar Ivy, Mark K. Friedberg, Dale A. BurkettChildren’s Hospital Colorado and University of Colorado – Anschutz Medical Campus. Hospital for Sick Children and University of Toronto.United States and Canada Circulation Cardiovascular ImagingCirc Cardiovasc Imag 2024; DOI: 10.1161/CIRCIMAGING.124.016882 AbstractBackground: Right ventricular-arterial coupling (RVAC) describes the relationship between right ventricular contractility and pulmonary vascular afterload.

Use of Right Ventricular Free-Wall Strain in a Multivariable Estimate of Right Ventricular-Arterial Coupling in Pediatric Pulmonary Arterial Hypertension Read More »

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