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Myocardial work during various right ventricle load conditions in a paediatric population

Ramona Ghenghea, Pierrick Pyra, Yves Dulac, Aitor Guitarte, Paul Vignaud, Philippe Acar, Khaled Hadeed, Clement KarsentyChildren’s Hospital, CHU Toulouse and Paul Sabatier University. France Achives of Cardiovascular DiseaseArch Cardiovasc Dis 2026; DOI: 10.1016/j.acvd.2025.11.013 AbstractBackground: Assessing right ventricular (RV) function in children is challenging, particularly in RV overload, where conventional echocardiographic indices do not account for afterload.Aims: This prospective […]

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Clinical Application of Inhaled Nitric Oxide in Conditions of Excessive Right Heart Load: A Review from Neonatal Pulmonary Hypertension to Perioperative Cardiac Surgery Management

Chengming Hu, Zhe Chen, Lizhi Lv, Yan Zhu, Yan Chen, Qiang WangBeijing Anzhen Hospital and Capital Medical University.China Journal of Cardiovascular Development and DiseaseJ Cardiovasc Drv Dis 2026; 13: DOI: 10.3390/jcdd13020081 AbstractExcessive right heart load imposes an acute or chronic injury on the right ventricle (RV), predisposing critically ill neonates and cardiac surgical patients to RV

Clinical Application of Inhaled Nitric Oxide in Conditions of Excessive Right Heart Load: A Review from Neonatal Pulmonary Hypertension to Perioperative Cardiac Surgery Management Read More »

Decreased AMP-Kinase Function in Pulmonary Artery Smooth Muscle Cells Contributes to Pulmonary Artery Remodeling in Persistent Pulmonary Hypertension of Newborn

Emily A. Mooers, Ujala Rana, Chintamani N. Joshi, Adeleye J. Afolayan, Ru-Jeng Teng, Girija Ganesh KonduriMedical College of Wisconsin. United States American Journal of Physiology Lung Cellular and Molecular PhysiologyAm J Physiol Lung Cell Mol Physiol 2026; DOI: 10.1152/ajplung.00229.2025 AbstractPulmonary vascular remodeling contributes to Persistent Pulmonary Hypertension of the Newborn (PPHN); the mechanisms remain unknown. 5’AMP-Activated

Decreased AMP-Kinase Function in Pulmonary Artery Smooth Muscle Cells Contributes to Pulmonary Artery Remodeling in Persistent Pulmonary Hypertension of Newborn Read More »

Titrating cumulative neonatal hyperoxia in mice to model bronchopulmonary dysplasia severities

Brooke Dir, Raveena Mishra, Nicole Hennen, Emily Mooers, Ru-jeng Teng, Ganesh Konduri, Jeffrey L. Segar, Justin Grobe, Matthew R. Hodges, Gary C. MouradianMedical College of Wisconsin. United States American Journal of Respiratory Cell and Molecular BiologyAm J Respir Cell Mol Biol 2026; DOI: 10.1093/ajrcmb/aanag031 AbstractThe severity of bronchopulmonary dysplasia (BPD) is defined by the type or

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Potts shunt in Pulmonary Arterial Hypertension: Timing and risk assessment

Zhuoyuan Xu, Xiafeng Yu, Yiwei Chen, Yanjun Sun, Lanping Wu, Wenjing Hong, Yumin Zhong, Jiaxuan Feng, Lijun Fu, Hao ZhangNational Children’s Medical Center, Shanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Shanghai Institute of Pediatric Congenital Heart Disease.China American Journal of Respiratory and Critical Care MedicineAm J Respir Crit Care Med

Potts shunt in Pulmonary Arterial Hypertension: Timing and risk assessment Read More »

Atrial fibrillation-induced severe left ventricular dysfunction postmitral valve replacement in an adolescent with rheumatic mitral regurgitation

Raghuraj Chawla, Yash Shrivastava, Anish Gupta, Bhanu DuggalAll India Institute of Medical Science Rishikesh.India British Medical Journal Case ReportsBMJ Case Rep 2026; 19: DOI: 10.1136/bcr-2025-267313 AbstractAn adolescent boy with a history of chronic rheumatic heart disease (RHD) and severe mitral regurgitation presented with progressive exertional dyspnoea and palpitations. Echocardiography revealed preserved left ventricular function preoperatively, and

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A hemodynamic-driven approach to chronic pulmonary hypertension in congenital diaphragmatic hernia

Carly E. Byrd, John T. Wren, Suneetha Desiraju, Patrick J. McNamaraJohns Hopkins University School of Medicine. University of Iowa Hospitals and Clinics.United States Journal of PerinatologyJ Perinatol 2026; DOI: 10.1038/s41372-026-02582-4 AbstractDespite ample research in acute pulmonary hypertension in neonates with congenital diaphragmatic hernia (CDH) leading to improved survival, there is a paucity of literature on the

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Echocardiographic screening for cardiovascular disease in central South Africa: expanding the role of echocardiography in patient referral

E. van der Heever, L. Botes, S. C. Brown, F. E. SmitUniversity of the Free State. South Africa Cardiovascular Journal of AfricaCardiovasc J Afr 2025; 36: 16-20DOI: 10.5830/CVJA-2024-012 AbstractIntroduction: Cardiovascular disease affects millions of people, resulting in significant rates of morbidity and mortality. Inadequate healthcare systems, combined with costly treatments, impose a high economic burden, with growing

Echocardiographic screening for cardiovascular disease in central South Africa: expanding the role of echocardiography in patient referral Read More »

Individualised interventional strategies and clinical outcomes in paediatric patients with pulmonary arterial hypertension

Emine Gulsah Torun, Oguzhan Dogan, Denizhan Bagrul, Ibrahim EceMinistry of Health Ankara Bilkent City Hospital.Turkey Cardiology in the YoungCardiol Young 2026; DOI: 10.1017/S104795112611141X AbstractObjective: This study evaluated the safety and efficacy of individualised interventional strategies in paediatric pulmonary arterial hypertension, focusing on the outcomes of atrial septostomy, reverse Potts shunt, and partial ASD closure in patients unresponsive

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Initial Hemodynamic Phenotypes and Clinical Trajectory in Congenital Diaphragmatic Hernia: A Pilot Study

John T. Wren Jr., Rachael M. Hyland, Patrick J. McNamaraUniversity of Iowa Healthcare.United States Journal of PediatricsJ Pediatr 2026; DOI: 10.1016/j.jpeds.2026.115044 AbstractObjectives: To define clinically the initial (<24 hour) hemodynamic phenotypes (no/mild pulmonary hypertension [PH], pre-capillary PH, and post-capillary PH) in neonates with congenital diaphragmatic hernia (CDH) by echocardiography, and to assess their relationship with clinical outcomes.Study

Initial Hemodynamic Phenotypes and Clinical Trajectory in Congenital Diaphragmatic Hernia: A Pilot Study Read More »

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