Fresh (PHresh). Less than 1-2 years since publication

Vein of Galen Malformation Masquerading as Neonatal Respiratory Distress

Hadi Fakih, Hussein A. Hussein, Fatima FakihSheikh Ragheb Harb University Hospital. Lebanese University. Lebanon Cureus Cureus 2026; 18: DOI: 10.7759/cureus.109082 AbstractVein of Galen malformation (VoGM) is a rare congenital vascular anomaly. It represents a well-recognized extracardiac cause of high-output cardiac failure in the neonatal period. We report a case of a 3.5-month-old boy who presented for […]

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Efficacy and safety of bosentan-related therapy in neonates with persistent pulmonary hypertension of the newborn: a systematic review and meta-analysis

Guanghong Li, Xiaoqun Du, Weibin Luo, Junhua Wei, Huiyi HuangHuadu District People’s Hospital of Guangzhou.China Frontiers in PediatricsFront Pediatr 2026; 14: DOI: 10.3389/fped.2026.1836276 AbstractObjective: To evaluate the efficacy and safety of bosentan-related therapy in neonates with persistent pulmonary hypertension of the newborn (PPHN).Methods: PubMed, Web of Science, the Cochrane Library, and ClinicalTrials.gov were searched from inception to March

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Clinical and echocardiographic characteristics of patients presenting with pulmonary hypertension due to congenital heart disease

M. M. F. Henema, F. E. Smit, S. C. Brown, L. BotesDr. George Mukhari Academic Hospital. Central University of Technology. University of the Free State. South Africa Cardiovascular Journal of AfricaCardiovasc J Afr 2026; 37: 53-61DOI: 10.5830/CVJA-2025-094 AbstractBackground: This study aimed to assess patients’ clinical and echocardiographic features in pulmonary hypertension (PH) due to congenital heart disease

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Recurrent Seizure-Like Events in a Toddler With BMPR2-Related Pulmonary Arterial Hypertension

Nur Sena Cagatay, Neha Ahluwalia, Aimee LuatChildren’s Hospital of Michigan.United States Ochsner JournalOchsner J 2026; 26: 179-182DOI: 10.31486/toj.25.0109 AbstractBackground: Seizure-like episodes are common in children, but many spells are not true epileptic seizures. Cardiac or pulmonary conditions such as pulmonary arterial hypertension can be the cause of the seizure-like episodes, particularly when the events persist despite administration

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Autologous stem cell transplantation (ASCT) for Refractory juvenile-onset systemic sclerosis (JSSc)

Kathryn S. Torok, Paulina Horvei, Jonathan Li, Franziska Rosser, Jessie L. Alexander, Kirsten Rose-felker, Vibha Sood, Adam Olson, Nicole Hogue, Vickie Vandergrift, Heather Stanczak, Maura Miglioretti, Lauren Farver, Wendy Koster, Devin Mcguire, Haley Havrilla, Shawna McIntyre, Robyn T. Domsic, Robert A. Lafyatis, Paul SzabolcsUniversity of Pittsburgh Medical Center (UPMC) and Children’s Hospital of Pittsburgh. Stanford

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Recent Advances in Pulmonary Hypertension Management

Sarah P. Cohen Alexandria L. Miller, Saurabh Rajpal, Scott H. VisovattiOhio State University School of Medicine and Nationwide Children’s Hospital. United States Heart Failure ClinicsHeart Fail Clin 2026; 22: 371-385DOI: 10.1016/j.hfc.2026.02.011 AbstractSignificant progress has been made in the management of pulmonary hypertension (PH), and especially pulmonary arterial hypertnesion (PAH), over the last 3 decades. Recent advances

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The Role of Machine Learning and Artificial Intelligence in Drug Discovery and Clinical Care of Pulmonary Hypertension

Evelyne Bischof, Chaim Haber, Niklas LidströmerShanghai University of Medicine and Health Sciences. Sheba Medical Center, Grey School of Medicine and Tel Aviv University. University of Copenhagen. Karolinska Institutet. China, Israel, Denmark and Sweden Heart Failure ClinicsHeart Fail Clin 2026; 22: 361-370DOI: 10.1016/j.hfc.2026.02.009 AbstractPulmonary hypertension (PH) is a severe and oftentimes fatal disease with a high degree

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An Ancient Founder GDF2 Variant Potentially Causes Semi-Dominant Non-Syndromic Pulmonary Arterial Hypertension

Abdullah Aldalaan, Seba Nadeef, Ebtissal Khouj, Fayez Alahmadi, Bayan Aljamal, Noura Alturaif, Nadeen Alharbi, Firdous Abdulwahab, Mashael Alqahtani, Fatima Alzubi, Omar Abuyousef, Mais O. Hashem, Hamdiah Zaytoun, Hanadi Alhamoud, Tarfa Alshidi, Amal Jaafar, Lama Alabdi, Fowzan S. AlkurayaKing Faisal Specialist Hospital and Research Center. Lifera Omics.Saudi Arabia Clinical GeneticsClin Genet 2026; DOI: 10.1111/cge.70191 AbstractGrowth differentiation factor

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Pulmonary Endarterectomy in Pediatric Patients: Institutional Experience

Çağatay Çetinkaya, Nezih Onur Ermerak, Ela Erdem, Figen Akalın, Koray Ak, Eylem Tuncer, Altuğ Sağır, Bedrettin Yildizeli BedrettinUskudar University. Marmara University. University of Health Sciences.Turkey Thoracic and Cardiovascular SurgeonThorac Cardiovasc Surg 2026; DOI: 10.1055/a-2875-1852 AbstractBackground: Chronic thromboembolic pulmonary hypertension (CTEPH) is rare in children and published experience with pulmonary endarterectomy (PEA) is limited.Methods: We retrospectively reviewed six patients

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Pediatric Pulmonary Infarction and Infarction-Like Pulmonary Injury: An Etiology-Oriented Narrative Review

Shuxuan Li, Yanran Zhang, Xiangxiang Tian, Wanqing Zhao, Yongsheng XuTianjin Medical University and Tianjin Children’s Hospital (Children’s Hospital of Tianjin University).China Seminars in Thrombosis and HemostasisSemin Thromb Hemost 2026; DOI: 10.1055/a-2889-7005 Abstract Pulmonary infarction (PI) has traditionally been regarded as a complication of pulmonary embolism (PE). However, increasing evidence suggests that pediatric PI represents a heterogeneous

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