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Barriers to and facilitators of physical activity in pediatric pulmonary hypertension

Catherine M. Avitabile, Caroline O’Brien, Divya Dureja, Dana Albizem, Jena Mota, Melissa Xanthopoulos, Babette S. Zemel, Peter F. CronholmChildren’s Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine and University of Pennsylvania.United States Pulmonary CirculationPulm Circ 2024; 14: DOI: 10.1002/pul2.70000 AbstractTherapeutic exercise has not been widely adopted in pediatric pulmonary hypertension (PH), despite adult data […]

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Cardiac Comorbidity and Exercise Intolerance in Bilateral Lung Transplant Recipients Followed at a Pediatric Center

Christina M. Mangano, Levent Midyat, Dawn Freiberger, Kimberlee Gauvreau, Debra Boyer, Gary Visner, Ming Hui ChenBoston Children’s Hospital and Harvard Medical School. University of Pittsburgh School of Medicine and Children’s Hospital of Pittsburgh. Nationwide Children’s Hospital and Ohio State University College of Medicine. United States Pediatric CardiologyPediatr Cardiol 2024; DOI: 10.1007/s00246-024-03674-8 AbstractReduced exercise capacity is common

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Inhalable Advanced Co-Spray Dried Microparticles/Nanoparticles of a Novel RhoA/Rho Kinase Inhibitor with Lung Surfactant Biomimetic Phospholipids for Targeted Lung Delivery

Victor H. Ruiz, David Encinas-Basurto, Neftali Ortega-Alarcon, Basanth Babu Eedara, Jeffrey R. Fineman, Stephen M. Black, Heidi M. MansourUniversity of Arizona College of Pharmacy, University of Arizona College of Medicine and University of Arizona. University of Sonora. Florida International University. University of California San Francisco School of Medicine. United States and Mexico American Chemical Society

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Vasopressin induced hyponatremia in infants <3 months of age in the neonatal intensive care unit

Kavita Patel, Sharon Thomson, Meera Vijayan, Marjorie Makoni, Peter N. Johnson, Katy Stephens, Stephen B. Neely, Jamie L. MillerUniversity Health, San Antonio. Oklahoma Children’s Hospital at Oklahoma University Health, University of Oklahoma College of Medicine and University of Oklahoma College of Pharmacy. Lucile Packard Children’s Hospital. United States Frontiers in PediatricsFront Pediatr 2024; 12DOI: 10.3389/fped.2024.1465785 AbstractObjectives: Vasopressin

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Echocardiographic evaluation of myocardial dysfunction in term neonates with perinatal asphyxia

Javaria Rasheed, Muhammad Khalid, Iram Nawaz, Barera MaryamNishtar Medical University Hospital. Bakhtawar Amin Medical & Dental College. Pakistan Pakistan Journal of Medical SciencesPak J Med Sci 2024; 40: 2107-2111DOI: 10.12669/pjms.40.9.9501 AbstractBackground and Objective: One third of the neonatal deaths worldwide are attributed to perinatal asphyxia. We aimed to determine the prevalence and determinants of cardiac dysfunction, through

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Survival, morbidity, and quality of life in pulmonary arterial hypertension patients: a systematic review of outcomes reported by population-based observational studies

Stefan Reinders, Eva‑Maria Didden, Rose OngActelion Pharmaceuticals and Johnson and Johnson.Peru and Switzerland Respiratory ResearchRespir Res 2024; 25: DOI: 10.1186/s12931-024-02994-w AbstractBackground: Comprehensive summaries on real-world outcomes in pulmonary arterial hypertension (PAH)-a rare, incurable condition, are lacking. We conducted a systematic literature review to describe current survival, morbidity, and quality of life (QoL) outcomes in adult and pediatric

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Utility of urinary NT-proBNP in congenital diaphragmatic hernia: a prospective pilot study

Srirupa Hari Gopal, Kelly Frances Martinek, Candice Vacher, Judith Becker, Nighy P. Varghese, Betul Yilmaz Furtun, Joseph L. Hagan, Sharada H. Gowda, Mohan Pammi, Sridevi Devaraj, Caraciolo J. FernandesBaylor College of Medicine.United States Pediatric ResearchPediatr Res 2024; DOI: 10.1038/s41390-024-03600-x AbstractBackground: Echocardiography is the reference standard for diagnosing pulmonary hypertension (PH) and cardiac dysfunction (CD) in congenital diaphragmatic

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Collapse of an early adolescent girl. Syncope? Simple or sinister?

Graham Martin, Chiara Cavaliere, Nikila Pandya, Krishnan BalasubramanianMaidstone and Tunbridge Wells NHS Trust.United Kingdom British Medical Journals Case ReportsBMJ Case Rep 2024; 17: DOI: 10.1136/bcr-2023-259246 AbstractAn early adolescent girl presented to the emergency department (ED) of her local hospital following a syncopal episode after a warm bath on a background of increasing breathlessness for 1-year duration. On examination, she

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Sildenafil as Bridge Therapy for Inhaled Nitric Oxide in Preterm Neonates

Harris Khawaja, Timothy A. Sanders, Michael Schreiber, Deborah Bondi, Pooja Shah, Gillian BrennanUniversity of Chicago Medicine and Comer Children’s Hospital.United States Journal of Pediatric Pharmacology and TherapeuticsJ Pediatr Pharmacol Ther 2024; 25: 525-529DOI: 10.5863/1551-6776-29.5.525 AbstractObjective: Inhaled nitric oxide (iNO) is a mainstay of treatment for infants with persistent pulmonary hypertension. However, abrupt discontinuation of inhaled nitric oxide

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Pharmacoepidemiology of combination pulmonary vasodilator therapy in critically ill infants

Karan R. Kumar, Elizabeth C. Ciociola, Kayla R. Skinner, Gargi M. Dixit, Sunshine Alvarez, Elijah K. Benjamin, Jeffrey C. Faulkner, Rachel G. Greenberg, Reese H. Clark, Daniel K. Benjamin Jr, Christoph P. Hornik, Jan Hau LeeDuke University School of Medicine. University of North Carolina School of Medicine. Pediatrix Center for Research. KK Women’s and Children’s

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