Fresh (PHresh). Less than 1-2 years since publication

Efficacy, Safety, and Pharmacokinetics of Macitentan in Japanese Pediatric Patients With Pulmonary Arterial Hypertension: Prospective, Multicenter, Open-Label Study

Ryo Inuzuka, Taku Ishii, Toru Iwasa, Kenichi Kurosaki, Ayako Kuraoka, Jun Narita, Shinichi Takatsuki, Masayoshi Nakano, Rieko Inagaki, Maki Mihoya, Kim Hyunsoo, Minaka Shibuya, Tohru Kobayashi, Hidekazu Ishida, Taichi Kato, Masaru Miura, Hiroyuki Yamagishi, Shozaburo DoiUniversity of Tokyo. Institute of Science Tokyo Hospital. National Cerebral and Cardiovascular Center. Fukuoka Children’s Hospital. University of Osaka Graduate

Efficacy, Safety, and Pharmacokinetics of Macitentan in Japanese Pediatric Patients With Pulmonary Arterial Hypertension: Prospective, Multicenter, Open-Label Study Read More »

Pediatric cardiomyopathy in a resource-limited setting: clinical characteristics and determinants of medium-term outcomes

Ghina Fakhri, Rana Zareef, Nour Younis, Nour Abdul Halim, Jad Abdul Khalek, Adham Makarem, Rand Ibrahim, Mohammed Ahmed, Fadi Fuad Bitar, Mariam Toufic ArabiAmerican University of Beirut Medical Center. American University of Beirut. Lebanon Frontiers in MedicineFront Med 2026; 13: DOI: 10.3389/fmed.2026.1800984 AbstractBackground and aims: Pediatric cardiomyopathy is the leading indication for cardiac transplantation in children. However,

Pediatric cardiomyopathy in a resource-limited setting: clinical characteristics and determinants of medium-term outcomes Read More »

The Pediatric Pulmonary Hypertension International Risk Score: A Prediction Model for Outcomes Using Machine Learning

Megan Griffiths, Bhargava K. Chinni, Chantel Lokhorst, Johannes M. Douwes, Lynn A. Sleeper, Jennifer Tingo, Steven H. Abman, Erika B. Rosenzweig, Jennifer E. Schramm, Eric D. Austin, Mary P. Mullen, Alba Torrent-Vernetta, Carlos Labrandero, Raymond Benza, Maria Jesus del Cerro, Rolf M. F. Berger, Cedric Manlhiot, Allen D. EverettUT Southwestern Medical Center. Johns Hopkins University.

The Pediatric Pulmonary Hypertension International Risk Score: A Prediction Model for Outcomes Using Machine Learning Read More »

Surviving Males With PORCN Variants: Expanding the Clinical, Molecular, and Mechanistic Spectrum

Lucía Miranda-Alcaraz, Simone Carbonera, Mónica Mora-Gómez, Natalia Gallego-Zazo, Inmaculada Guillén, Elena Padilla, Gaia Visani, Alessia Asaro, Valeria Vásquez-Amell, Mario Cazalla, Manuel Rodríguez-Canó, Cristina Silván, Pedro Arias, Juan Andrés Jiménez-Estrada, Tomás Valle, Alejandro Cruz-Utrilla, Pilar Escribano-Subías, Nuria Ochoa Parra, María Jesús del Cerro Marín, Julián Nevado, Spanish PAH Consortium, Pablo Lapunzina, Fabio Sirchia, Jair Tenorio-CastanoHospital Universitario

Surviving Males With PORCN Variants: Expanding the Clinical, Molecular, and Mechanistic Spectrum Read More »

Transcatheter atrial flow regulator implantation in children with pulmonary arterial hypertension in resource-limited settings: a single-centre experience

Bibhuti Das, Shreesha Maiya, Basha Khan, Vimal Raj, Shashi RajMethodist Children’s Hospital. Narayana Institute of Cardiac Sciences. United States and India Cardiology in the YoungCardiol Young 2026; DOI: 10.1017/S1047951126123555 AbstractPulmonary arterial hypertension in children remains a progressive disease marked by right ventricular failure and early mortality despite advances in targeted therapy. In resource-limited settings, access to

Transcatheter atrial flow regulator implantation in children with pulmonary arterial hypertension in resource-limited settings: a single-centre experience Read More »

Pulmonary Hypertension with a High-Output Hemodynamic Profile in a Child with MELAS: A Case Report

Miki Kanai, Hirofumi Tsuru, Takanori Onuki, Shunsuke Nukaga, Shigehito Baba, Masanori Tsukada, Tadaaki Abe, Fujito Numano, Kei Murayama, Akihiko SaitohSaiseikai Niigata Kenoh Kikan Hospital. Niigata University School of Medicine. Juntendo University. Japan Internal MedicineIntern Med 2026; DOI: 10.2169/internalmedicine.7614-26 AbstractPulmonary hypertension (PH) is uncommon in myopathy, encephalopathy, lactic acidosis, and stroke-like (MELAS) and its hemodynamics are poorly

Pulmonary Hypertension with a High-Output Hemodynamic Profile in a Child with MELAS: A Case Report Read More »

Pulmonary hypertension and acute hypoxic respiratory failure in preterm neonates

Marwa M. Elgendy, Sfurti NathUniversity of Maryland School of Medicine. Warren Alpert Medical School of Brown University.United States Journal of PerinatologyJ Perinatol 2026; DOI: 10.1038/s41372-026-02858-9 AbstractPulmonary hypertension (PH) in preterm infants is a complex and heterogeneous condition that significantly contributes to hypoxic respiratory failure (HRF), bronchopulmonary dysplasia (BPD), and mortality. Unlike term infants, PH in preterm

Pulmonary hypertension and acute hypoxic respiratory failure in preterm neonates Read More »

The Heterogeneity of Long-Term Cardiopulmonary Outcomes in Children Born Preterm May Benefit from Pulmonary Hypertension-Specialty Outpatient Follow-Up

Meaghan C. Rousset, Rachel T. Sullivan, Anna M. Brown, Samantha R. Eagle, Eric D. AustinVanderbilt University Medical Center. United States Pulmonary CirculationPulm Circ 2026; 16: DOI: 10.1002/pul2.70380 AbstractPreterm birth survivors reaching adulthood are a growing population, with bronchopulmonary dysplasia (BPD), the chronic lung disease of prematurity, common among this cohort. Infants with BPD are at increased

The Heterogeneity of Long-Term Cardiopulmonary Outcomes in Children Born Preterm May Benefit from Pulmonary Hypertension-Specialty Outpatient Follow-Up Read More »

Left Atrial Myopathy Across the Spectrum of Pediatric Heart Disease: Imaging, Mechanobiology, and Clinical Consequences

Raima Muqaddas, Sania Nawaz, Sarah Ali, Fatima Aamir, Andleeb Shafique, Khadija Shaukat, Zainab Shakeel Ahmed, Laiba Munawar, Ayrass ZiaFaisalabad Medical University. Azra Naheed Medical College. Rawalpindi Medical University. Allama Iqbal Medical College. Baqai Medical University. Islam Medical and Dental College. Fatima Jinnah Medical University. Pakistan Cardiology in ReviewCardiol Review 2026; DOI: 10.1097/CRD.0000000000001426 AbstractLeft atrial (LA) function has

Left Atrial Myopathy Across the Spectrum of Pediatric Heart Disease: Imaging, Mechanobiology, and Clinical Consequences Read More »

Development and validation of a nomogram prediction model for mild pulmonary arterial hypertension risk in children with left-to-right shunt congenital heart disease

Suyuan Qin, Lifeng Shang, Danyan Su, Bingbing Ye, Yuqin Huang, Yanyun Huang, Yusheng PangFirst Affiliated Hospital of Guangxi Medical University, Difficult and Critical Illness Center and the Pediatric Clinical Medical Research Center of Guangxi.China MedicineMedicine 2026; 105:DOI: 10.1097/MD.0000000000050136 AbstractMild pulmonary arterial hypertension (PAH) represents an early and potentially reversible complication stage in children with congenital structural

Development and validation of a nomogram prediction model for mild pulmonary arterial hypertension risk in children with left-to-right shunt congenital heart disease Read More »

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