Farnaz Ahmadi, Raha Parnia, Bahamin Astani, Mohammad-Sadegh Keshmiri, Shakiba Khodadad, Hakimeh Sheikhzadeh, Zahra Daneshmandi, Faezeh Ansari, Mahsa Riahi, Sima Noorali, Hannaneh Yousefi-Koma, Babak Sharif-Kashani, Shadi Shafaghi
Shahid Beheshti University of Medical Sciences. Simon Fraser University. Erfan Hospital. Mofid Children’s Hospital. Masih Daneshvari Hospital.
Iran, Canada
Research in Heart Yield and Translational Medicine
Res Heart Yield Transl Med 2026; 21: 111-115
DOI: 10.18502/jthc.v21i1.21288
Abstract
Highlights: Pregnancy is typically contraindicated in women with pulmonary hypertension (PH) due to severe mortality risks.A 31-year-old woman with PH, secondary to previous hydatid cysts, conceived against medical advice while on medical therapy. She successfully delivered via emergency C-section at 37 weeks. Her case highlights those high-risk pregnancies complicated by PH can be successfully managed through prompt, multidisciplinary care at a specialized tertiary center.
Background: Pregnancy in women with pulmonary hypertension (PH) is contraindicated because of high mortality rates associated with physiological changes, particularly in the peripartum and postpartum periods. Termination is recommended early if pregnancy occurs. Consequently, clinical experience with continued pregnancy in patients with PH is scarce.
Case presentation: A 31-year-old woman was diagnosed with multiple bilateral pulmonary and right ventricular hydatid cysts. After surgical and pharmacologic treatments, she developed PH due to pulmonary artery obstruction 8 years later. Because of her condition, she was ineligible for surgery and received medical therapy, including tadalafil, bosentan, and eplerenone. After 3 years, she conceived despite advice to avoid pregnancy. At 37 weeks’ gestation, she underwent successful emergency cesarean delivery because of maternal dyspnea and tachycardia.
Conclusion: Prompt treatment and regular follow-up in a tertiary care center using a multidisciplinary approach are crucial for managing pregnant patients with PH.
Category
Class IV. Pulmonary Hypertension Associated with Thromboembolic Disease
Procedural Risk and Care for Individuals with Pulmonary Vascular Disease
Age Focus: Adult Pulmonary Vascular Disease
Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication
Article Access
Free PDF File or Full Text Article Available Through PubMed or DOI: Yes