Diagnostic Testing for Pulmonary Vascular Disease. Invasive Testing

Prolonged Postnatal Hypoxia Impairs Lung Development and Causes Severe Pulmonary Hypertension in Mice

Luca Zazzeron, Kakeru Shimoda, Paul Lichtenegger, Elizabeth Moore, Helena Tattersfield, Alexandra K. Marenco, Jiayi Kang, Haobo Li, Eizo Marutani, Donald B. Bloch, Fumito IchinoseMassachusetts General Hospital and Harvard Medical School. United States Journal of the American Heart AssociationJ Am Heart Assoc 2025; DOI: 10.1161/JAHA.125.042608 AbstractBackground: In children born at high altitude, lung development is affected by hypoxia, which can lead to pulmonary hypertension and right ventricular failure. […]

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Porto-Pulmonary Hypertension in Children: Insights From a National Registry

Sadia Quyam, Alastair Baker, Alistair Calder, Shahin MoledinaGreat Ormond Street Hospital for Children. University College London. King’s College Hospital .Inited Kingdom Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70133 AbstractPorto-pulmonary hypertension (PoPH) represents a rare but significant form of pulmonary arterial hypertension (PAH) in children. Despite its clinical importance, systematic analyses of paediatric presentations and outcomes remain limited.

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Right atrial function is impaired in pediatric pulmonary arterial hypertension: a multi-center cardiac MRI study

Kimberley G. Miles, Hieu T. Ta, Kurt R. Bjorkman, Zhiqian Gao, Nicholas J. Ollberding, Russel Hirsch, D. Dunbar Ivy, Sean M. Lang, Michelle Cash, Melissa Magness, Meredith O’Neil, Kimberly Luebbe, Benjamin S. Frank, Paul J. CritserCincinnati Children’s Hospital Medical Center and University of Cincinnati College of Medicine. Helen DeVos Children’s Hospital. University of Colorado School

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International Society for Heart and Lung Transplantation (ISHLT) Consensus Statement on Risk Stratification in Pulmonary Arterial Hypertension

Sandeep Sahay 1, Scott Visovatti 2, Adriano R Tonelli 3, Nelson Villasmil Hernandez 4, Eric D Austin 5, Roberto Badagliacca 6, Rolf M F Berger 7, Athénaïs Boucly 8, Yucheng Chen 9, Colin Church 10, Marion Delcroix 11, Allen D Everett 12, Harrison W Farber 13, Charles Fauvel 14, Mardi Gomberg-Maitland 15, Megan Griffiths 16, Francois Haddad 17, Yuchi Han 18, Anna Hemnes 5, Marius M Hoeper 19, Manreet K Kanwar 20, Daniel Lachant 21, Sandhya Murthy 22, Karen M Olsson 19, Ioana Preston 23, Göran Rådegran 24, Olivier Sitbon 25, Maria G Trivieri 26, Jean-Luc Vachiery 27, Rebecca Vanderpool 2, Jason Weatherald 28, R James White 21, Helen Whitford 29, Melisa Wilson 30, Raymond L Benza  Houston Methodist Hospital. Ohio State University.

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Pulmonary Vascular Compromise Is Associated With Survival in Pediatric Pulmonary Hypertension: A New Computational Model

Maria Niccum, Catherine M. Avitabile, Dana Albizem, Heather Meluskey, Christopher Penney, Brian D. Hanna, Michael L. O’Byrne, Zoheir Bshouty, David B. FrankPerelman School of Medicine at the University of Pennsylvania and Children’s Hospital of Philadelphia. University of Manitoba.United States and Canada Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70156 AbstractPediatric pulmonary arterial hypertension (PAH) has a long

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Echocardiographic Assessment of Pulmonary Hemodynamics and Right Ventricular Performance in Neonatal Murine Hypoxia

Kel Vin Woo, Philip T. Levy, Carla J. Weinheimer, Amanda L. Hauck, Aaron Hamvas, David M. Ornitz, Attila Kovacs, Gautam K. SinghWashington University School of Medicine. Boston Children’s Hospital, Department of Pediatrics and Harvard Medical School. Ann and Robert H. Lurie Children’s Hospital of Chicago and Northwestern University Feinberg School of Medicine. Children’s Hospital Michigan

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Case Report: Non-reactive vasoreactivity testing in a patient with patent ductus arteriosus with pulmonary hypertension: is there still a way to turn things around?

Sisca Natalia Siagian, Elsa Hedia Panjaitan, Pandu Prasetyo NugrohoUniversitas Indonesia.Indonesia Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2025; 12: DOI: 10.3389/fcvm.2025.1569963 AbstractBackground: Recent guidelines recommend patent ductus arteriosus (PDA) closure in adults based on hemodynamic criteria, such as pulmonary vascular resistance (PVR) and flow ratio (Qp:Qs). However, additional parameters like acute vasoreactivity testing (AVT) and closure testing, though

Case Report: Non-reactive vasoreactivity testing in a patient with patent ductus arteriosus with pulmonary hypertension: is there still a way to turn things around? Read More »

Challenges in accurately assessing acute vasoreactivity in paediatric pulmonary arterial hypertension: case reports highlighting the impact of sedation on diagnostic accuracy

Kana Inoue, Taku Ishii, Yohei Yamaguchi, Satoshi Nagahara, Makito Sakurai, Susumu Hosokawa, Shozaburo DoiInstitute of Science Tokyo. Chiba Kaihin Municipal Hospital. Musashino Red Cross Hospital. Tokyo Healthcare University.Japan European Heart Journal Case ReportsEur Heart J Case Rep 2025; 9: DOI: 10.1093/ehjcr/ytaf357 AbstractBackground: Initial treatment based on acute vasoreactivity test results is essential for idiopathic or hereditary pulmonary

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Pharmacologic Management of Segmental Pulmonary Hypertension in Children After Unifocalization and Pulmonary Artery Reconstruction: Initial Experience

Julian E. Cameron, Doff B. McElhinney, Esther Liu, Rachel K. Hopper, Ritu Asija, Manchula Navaratnam, Frank L. Hanley, Jeffrey A. FeinsteinLucile Salter Packard Children’s Hospital and Stanford University School of Medicine. Children’s Hospital Los Angeles and Keck School of Medicine University of Southern California.United States Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70134 AbstractSegmental pulmonary hypertension (PH)

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Sound Waves Versus Pressure Waves: The Increasing Role of Echocardiography and Noninvasive Vasoreactivity Testing in Pediatric Pulmonary Hypertension Management

John T. Wren Jr., Kamel ShibbaniUniversity of Iowa.United States EchocardiographyEchocardiography 2025; 42: DOI: 10.1111/echo.70254 AbstractAbstract Not Available CategoryDiagnostic Testing for Pulmonary Vascular Disease. Non-invasive TestingDiagnostic Testing for Pulmonary Vascular Disease. Invasive Testing Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication Article Access Free PDF File or

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