Diagnostic Testing for Pulmonary Vascular Disease. Invasive Testing

A Case of Embolization of a Lymphatic Malformation Complicated by Chylothorax, Chylopericardium, and Interstitial Lung Disease in a 6-Year-Old Pediatric Patient

Eleonora Rossi, Duccio Rossi, Mario Petrillo, Gianpaolo Carrafiello, Andrea Antonio IannielloUniversità degli Studi di Milano. Luigi Sacco Hospital. IRCCS Ca’Granda Fondazione Ospedale Maggiore Policlinico. Italy Case Reports in RadiologyCase Rep Radiol 2026; DOI: 10.1155/crra/1095827 AbstractBackground: A 6-year-old child with a clinical history of chylopericardium treated with pericardiocentesis presented with retrosternal chest pain and asthenia in the past […]

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Impact of Thermodilution on Indexed Pulmonary Vascular Resistance Calculations in Pediatric Pulmonary Arterial Hypertension

Daiji Takajo, Paul J. Critser, Russel HirschCincinnati Children’s Hospital Medical Center and University of Cincinnati.United States Pediatric PulmonologyPediatr Pulmonol 2026; 61:DOI: 10.1002/ppul.71787 AbstractBackground: Accurate assessment of pulmonary vascular resistance index (PVRi) is essential for the diagnosis and management of pulmonary arterial hypertension (PAH). PVRi depends on pulmonary blood flow (Qp), which can be determined by thermodilution or

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The Pediatric Pulmonary Hypertension International Risk Score: A Prediction Model for Outcomes Using Machine Learning

Megan Griffiths, Bhargava K. Chinni, Chantel Lokhorst, Johannes M. Douwes, Lynn A. Sleeper, Jennifer Tingo, Steven H. Abman, Erika B. Rosenzweig, Jennifer E. Schramm, Eric D. Austin, Mary P. Mullen, Alba Torrent-Vernetta, Carlos Labrandero, Raymond Benza, Maria Jesus del Cerro, Rolf M. F. Berger, Cedric Manlhiot, Allen D. EverettUT Southwestern Medical Center. Johns Hopkins University.

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Pilot study to validate endothelium collection from pulmonary artery balloon catheter in children

Maxwell Mathias, Charles Sperrazza, Anas Salkini, Andrew Cave, Courtney T. Griffin, Venkatachalem Sathish, Subhrajit LahiriUniversity of Oklahoma Health College of Medicine. Oklahoma Medical Research Foundation. United States Pediatric ResearchPediatr Res 2026; DOI: 10.1038/s41390-026-05326-4 AbstractPediatric pulmonary hypertension (PH) has high morbidity and mortality, with an estimated 5-year survival of 75% regardless of underlying cause. Pediatric PH most

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Growth-adjusted reference values for the main pulmonary artery-to-ascending aorta ratio derived from clinically indicated chest CT in children

Ying Lyu, Mingshu Yang, Huaqin Bu, Chao Gong, Jinhua Ma, Tingting Luo, Li Zhong, Yongle Zhao, Xiao Yang, Ting Wang, Yan Chen, Daiyin TianChildren’s Hospital of Chongqing Medical University and National Clinical Research Center for Children and Adolescents’ Health and Diseases. Children’s Hospital of Fudan University and National Children’s Medical Center. China European RadiologyEur Radiol

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Novel echocardiographic markers for the assessment of pulmonary hypertension in infants

Sarah Diamond, Beverly Spray, Amna Qasim, Peter M. Mourani, Amit Agarwal, Michael Angtuaco, Ankita Shukla, Richard W. Hall, Megha SharmaUniversity of Arkansas for Medical Sciences and Arkansas Children’s Research Institute. University of Michigan. Baylor College of Medicine. United States Journal of PerinatologyJ Perinatol 2026; DOI: 10.1038/s41372-026-02748-0 AbstractPulmonary hypertension (PH) confers significant morbidity and mortality in infants.

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Diffusion of carbon monoxide in the lungs and pulmonary artery pressures in school aged children who were born preterm

Christopher Harris, Allan Jenkinson, Sanja Zivanovic, Kuberan Pushparajah, Theodore Dassios, Steven H. Abman, Anne GreenoughKing’s College London, King’s College Hospital NHS Foundation Trust and Imperial College Healthcare NHS Trust. University of Colorado School of Medicine.united Kingdom and United States Pediatric ResearchPediatr Res 2026; DOI: 10.1038/s41390-026-05260-5 AbstractBackground: Premature birth is associated with altered pulmonary vascular development and raised

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Cardiac Index Measured Using the Fick Principle Versus Thermodilution in Children Following Orthotopic Heart Transplantation

Elyssa Cohen, Conor O’Halloran, Nicholas Pilli, Paul TannousAnn and Robert H. Lurie Children’s Hospital of Chicago.United States Pediatric CardiologyPediatr Cardiol 2026; DOI: 10.1007/s00246-026-04302-3 AbstractCardiac index (CI) is used to assess graft function and calculate pulmonary vascular resistance (PVR) following orthotopic heart transplantation (OHT). The gold standard is thermodilution (TD), but in practice, the Fick method using

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Registry-based estimation of cardiac event-free survival in congenital heart disease complicated by pulmonary hypertension: A nationwide registry study from Japan

Taku Ishii, Tatsuhiko Anzai, Keiko Uchida, Susumu Hosokawa, Naofumi F. Sumitomo, Hidekazu Ishida, Keiichi Hirono, Jun Muneuchi, Ayako Chida-Nagai, Ryo Inuzuka, Hirofumi Sawada, Sayo Suzuki, Jun Maeda, Hisaaki Aoki, Lisheng Lin, Takashi Murakami, Yusuke Nakano, Tatsuya Onishi, Takuya Wakamiya, Kei Inai, Shinichi Takatsuki, Atsushi Yao, Shigetoyo Kogaki, Hiroyuki Fukushima, Yuichi Tamura, Kunihiko Takahashi, Hiroyuki Yamagishi,

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Cardiac Catheterization for Assessment of Pulmonary Hypertension in Preterm Lambs

Yasmine N. White, Matthew Douglass, Jakob Van Boerum, Andrew Rebentisch, Kurt H. Albertine, Mar Janna DahlUniversity of Utah.United States Journal of Visualized ExperimentsJ Vis Exp 2026; DOI: 10.3791/70620 AbstractBronchopulmonary dysplasia with pulmonary hypertension (BPD-PH) is a devastating complication of preterm birth that is associated with increased morbidity and mortality. Preterm birth disrupts normal lung and vascular

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