Class 3. Pulmonary Hypertension Associated with Lung Hypoplasia

Treprostinil Use in the NICU

Diana LeeUniversity of Pennsylvania School of Nursing.United States Advances in Neonatal CareAdv Neonat Care 2024; 24: 554-560DOI: 10.1097/ANC.0000000000001218 AbstractBackground: Treprostinil is a prostacyclin analogue that is frequently used in the pediatric and adult population to treat pulmonary hypertension; however, it is not often a drug of choice for patients in the neonatal intensive care unit (NICU).Purpose: To evaluate […]

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Two-Year Outcomes in Preterm Infants Suffering from Moderate to Severe Bronchopulmonary Dysplasia with or without Associated Pulmonary Hypertension

Irina Branescu, Dragos Ovidiu Alexandru, Simona Vladareanu, Anay KulkarniCarol Davila University of Medicine and Pharmacy. St. George’s University Hospital and St George’s University. University of Medicine and Pharmacy. Royal Brompton Hospital NHS Foundation Trust.Romania and United Kingdom Current Health Sciences JournalCurr Health Sci J 2024; 50: 436-443DOI: 10.12865/CHSJ.50.03.11 AbstractObjectives: To assess the impact of pulmonary hypertension (PH)

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microRNAs in Congenital Diaphragmatic Hernia: Insights into Prenatal and Perinatal Biomarkers and Altered Molecular Pathways: microRNAs in Congenital Diaphragmatic Hernia for Pathway Analysis and Prognostic Biomarkers

James R. Bardill, Anis Karimpour-Fard, Courtney C. Breckenfelder, Carmen C. Sucharov, Caitlin R. Eason, Lauren T. Gallagher, Ludmila Khailova, Clyde J. Wright, Jason Gien, Henry L. Galan, S. Christopher DerderianUniversity of Colorado School of Medicine and Children’s Hospital Colorado. United States American Journal of Obstetrics and Gynecology Maternal and Fetal MedicineAm J Obstet Gynecol MFM

microRNAs in Congenital Diaphragmatic Hernia: Insights into Prenatal and Perinatal Biomarkers and Altered Molecular Pathways: microRNAs in Congenital Diaphragmatic Hernia for Pathway Analysis and Prognostic Biomarkers Read More »

The cardiopulmonary benefits of physiologically based cord clamping persist for at least 8 hours in lambs with a diaphragmatic hernia

Paige J. Riddington, Philip L. J. DeKoninck, Marta Thio, Calum T. Roberts, Risha Bhatia, Janneke Dekker1, Aidan J. Kashyap, Benjamin J. Amberg, Karyn A. Rodgers, Alison M. Thiel, Ilias Nitsos, Valerie A. Zahra, Ryan J. Hodges, Stuart B. Hooper, Kelly J. CrossleyHudson Institute of Medical Research. Monash University. Erasmus MC University Medical Center-Sophia Children’s Hospital.

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Could a Two-Staged Repair Be the Solution to the Dilemma of Repair Timing for Severe Congenital Diaphragmatic Hernia Requiring Extracorporeal Membrane Oxygenation?

Akiko YokoiKobe Children’s Hospital.Japan ChildrenChildren 2024; 11:DOI: 10.3390/children11101255 AbstractPurpose of review: Congenital diaphragmatic hernia (CDH) remains a significant challenge, particularly in severe cases with persistent pulmonary hypertension (PPHN) and hypoplastic lungs and heart. For patients unresponsive to conventional therapies, ECMO is required. While the surgical repair is relatively simple, determining the optimal timing for surgery in patients

Could a Two-Staged Repair Be the Solution to the Dilemma of Repair Timing for Severe Congenital Diaphragmatic Hernia Requiring Extracorporeal Membrane Oxygenation? Read More »

Ventricular Dysfunction in Patients With Congenital Diaphragmatic Hernia Who Die After Repair

Catherine M. Avitabile, Yang Wang, Devon Ash, Sabrina J. Flohr, Leny Mathew, Natalie Rintoul, Holly L. HedrickPerelman School of Medicine at the University of Pennsylvania and Children’s Hospital of Philadelphia. United States Journal of Pediatric SurgeryJ Pediatr Surg 2024; 60: DOI: 10.1016/j.jpedsurg.2024.162002 AbstractBackground: Quantitative echocardiographic (echo) measures of ventricular function predict mortality in pediatric pulmonary hypertension (PH),

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Utility of urinary NT-proBNP in congenital diaphragmatic hernia: a prospective pilot study

Srirupa Hari Gopal, Kelly Frances Martinek, Candice Vacher, Judith Becker, Nighy P. Varghese, Betul Yilmaz Furtun, Joseph L. Hagan, Sharada H. Gowda, Mohan Pammi, Sridevi Devaraj, Caraciolo J. FernandesBaylor College of Medicine.United States Pediatric ResearchPediatr Res 2024; DOI: 10.1038/s41390-024-03600-x AbstractBackground: Echocardiography is the reference standard for diagnosing pulmonary hypertension (PH) and cardiac dysfunction (CD) in congenital diaphragmatic

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Pharmacoepidemiology of combination pulmonary vasodilator therapy in critically ill infants

Karan R. Kumar, Elizabeth C. Ciociola, Kayla R. Skinner, Gargi M. Dixit, Sunshine Alvarez, Elijah K. Benjamin, Jeffrey C. Faulkner, Rachel G. Greenberg, Reese H. Clark, Daniel K. Benjamin Jr, Christoph P. Hornik, Jan Hau LeeDuke University School of Medicine. University of North Carolina School of Medicine. Pediatrix Center for Research. KK Women’s and Children’s

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Utility of the oxygenation index in management of congenital diaphragmatic hernia: a report from a Thai University Surgical Centre

Issariyaporn Kulngamnetr, Pharuhad Pongmee, Paul D. Losty, Suraida Aeesoa, Ampaipan BoonthaiRamathibodi Hospital and Mahidol University. University of Liverpool. Thailand and United Kingdom Pediatric Surgery InternationalPediatr Surg Int 2024; 40: DOI: 10.1007/s00383-024-05848-0 AbstractBackground: Oxygenation index (OI) is associated with severity of newborn pulmonary hypertension (PH) in congenital diaphragmatic hernia (CDH). Higher OI may indicate worst degree(s) of PH.Objectives: This

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Patterns and Outcomes of Epoprostenol Use in Infants with Congenital Diaphragmatic Hernia Requiring Extracorporeal Life Support

Nikhil R. Shah, Keerthi Burgi, Dimitra M. Lotakis, Mary K. Olive, Amanda D. McCormick, Erin E. Perrone, Joseph T. Church, George B. MychaliskaC.S. Mott Children’s Hospital, Michigan Medicine and University of Michigan Medical School. United States Journal of PediatricsJ Pediatr 2024; DOI: 10.1016/j.jpeds.2024.114286 AbstractObjective: To describe our experience utilizing epoprostenol for pulmonary hypertension (PH) in infants with

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