Class 3. Pulmonary Hypertension Associated with Lung Disease

Bronchopulmonary dysplasia, pulmonary hypertension, and neonatal gastroesophageal reflux: Association, causation, or neither?

Erik A. JensenStanford University School of Medicine and Lucile Packard Children’s Hospital.United States Seminars in PerinatologySemin Perinatol 2025; DOI: 10.1016/j.semperi.2025.152158 AbstractBronchopulmonary dysplasia (BPD) is among the most common and serious complications of prematurity. The pathobiology of BPD and BPD associated pulmonary arterial hypertension (BPD-PH) is multifactorial and not yet fully defined. Gastroesophageal reflux (GER), a physiologic

Bronchopulmonary dysplasia, pulmonary hypertension, and neonatal gastroesophageal reflux: Association, causation, or neither? Read More »

Trends, Burden, and Inequality in Neonatal Pulmonary Arterial Hypertension: Global Estimates From 1990 to 2021

Xinbao Wang, Zhe Tang, Ziwei WangBeijing Friendship Hospital and Capital Medical University.China Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.71277 AbstractBackground: Pulmonary arterial hypertension (PAH) is a rare but life-threatening disorder in neonates, characterized by increased pulmonary vascular resistance and right heart failure. Despite advances in neonatal intensive care, the global burden of neonatal PAH remains poorly defined,

Trends, Burden, and Inequality in Neonatal Pulmonary Arterial Hypertension: Global Estimates From 1990 to 2021 Read More »

Pulmonary Hypertension Outcomes After Closure of Atrial Septal Defect in Infants With Developmental Lung Disease

John L. Wiegand, James A. Thompson, Bruce F. Landeck, Jamie L. Fierstein, Dina Ashour, Joana S. Machry, Amy L. Kiskaddon, Marisol Betensky, Grace A. FreireUniversity of South Florida Morsani College of Medicine. Johns Hopkins All Children’s Hospital. United States Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70164 AbstractPulmonary hypertension (PHTN) in infants with developmental lung disease, such

Pulmonary Hypertension Outcomes After Closure of Atrial Septal Defect in Infants With Developmental Lung Disease Read More »

Respiratory Outcomes Following Late Postnatal Dexamethasone Administration in Preterm Infants With Bronchopulmonary Dysplasia

Melissa House, James Rowe, Audrey Walters, Chunyan Liu, Shelley R. Ehrlich, Thomas Nienaber, Erik B. Hysinger, Paul Kingma, Shawn K. AhlfeldEmory University School of Medicine and Children’s Healthcare of Atlanta. Cincinnati Children’s Hospital Medical Center and University of Cincinnati College of Medicine.United States Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.71275 AbstractObjective: To wean respiratory support, preterm infants

Respiratory Outcomes Following Late Postnatal Dexamethasone Administration in Preterm Infants With Bronchopulmonary Dysplasia Read More »

Screening for pulmonary hypertension in preterm infants with bronchopulmonary dysplasia: when, how often and does it matter?

Samuel J. Gentle, Waldemar A. Carlo, Namasivayam AmbalavananUniversity of Alabama at Birmingham. Yale School of Medicine.United States Archives of Disease in Childhood Fetal and Neonatal EditionArch Dis Child Fetal Neonatal Ed 2025; DOI: 10.1136/archdischild-2024-328405 AbstractObjective: Bronchopulmonary dysplasia (BPD) associated pulmonary hypertension (BPD-PH) is the most severe endotype of BPD; there is insufficient evidence to support the optimal

Screening for pulmonary hypertension in preterm infants with bronchopulmonary dysplasia: when, how often and does it matter? Read More »

p53 maintains lineage fidelity during lung capillary injury-repair in neonatal hyperoxia

Lisandra Vila Ellis, Jonathan D. Bywaters, Amanda Ceas, Yun Liu, Jennifer M. S. Sucre, Jichao ChenNorthwestern University.  Vanderbilt University Medical Center. Cincinnati Children’s Hospital Medical Center.United States Journal of Clinical Investigation InsightsJCI Insights 2025;DOI: 10.1172/jci.insight.182880 AbstractBronchopulmonary dysplasia (BPD), a prevalent and chronic lung disease affecting premature newborns, results in vascular rarefaction and alveolar simplification. Although the

p53 maintains lineage fidelity during lung capillary injury-repair in neonatal hyperoxia Read More »

Clinical Characteristics and Outcomes for Neonates with Respiratory Failure Referred for Extracorporeal Membrane Oxygenator (ECMO) Support

Pooja Musuku, Keith Meyer, Felipe E. Pedroso, Fuad Alkhoury, Balagangadhar R. TotapallyNicklaus Children’s Hospital. Herbert Wertheim College of Medicine and Florida International University.United States ChildrenChildren 2025; 12: DOI: 10.3390/children12070925 AbstractObjective: The aim of this study was to describe the presenting characteristics and outcomes of neonates with respiratory failure referred for extracorporeal membrane oxygenation (ECMO) support, compare

Clinical Characteristics and Outcomes for Neonates with Respiratory Failure Referred for Extracorporeal Membrane Oxygenator (ECMO) Support Read More »

Impact of Pulmonary Hypertension and Patent Ductus Arteriosus in Preterm Infants with Presumed Pulmonary Hypoplasia

Sol Kim, Yumi Seo, Moon-Yeon Oh, Min Soo Kim, Sook Kyung YumSeoul St. Mary’s Hospital and Catholic University of Korea.Republic of Korea BiomedicinesBiomedicines 2025; 13: DOI: 10.3390/biomedicines13071725 AbstractObjectives: Pulmonary hypertension and hemodynamically significant PDA (hsPDA) involve seemingly opposite physiological features-decreased pulmonary blood flow and pulmonary overcirculation, respectively-but the literature demonstrates variable respiratory consequences in association with

Impact of Pulmonary Hypertension and Patent Ductus Arteriosus in Preterm Infants with Presumed Pulmonary Hypoplasia Read More »

Outcomes of extremely preterm infants with bronchopulmonary dysplasia: a retrospective cohort study

Ashraf Gad, Rowan Mesilhy, Thomas Maveli, FatimaAli, Noora Jasim, MalazAdam, Tasneim Abdalla, Mohamed Madani, Mohammad Ayman Alkhateeb, Mohammad A. A. BayoumiHamad Medical Corporation. Qatar University. Sidra Medicine. Qatar Scientific ReportsSci Rep 2025; 15: DOI: 10.1038/s41598-025-12066-8 AbstractTo investigate the respiratory and related health outcomes at 18 months for extremely preterm (EP) infants diagnosed with bronchopulmonary dysplasia (BPD).

Outcomes of extremely preterm infants with bronchopulmonary dysplasia: a retrospective cohort study Read More »

The effectiveness of pulmonary hypertension screening in infants born preterm

Stephanie Vachon, Rajiv Devanagondi, Andrew Dylag, Hongyue Wang, Gloria PryhuberUniversity of Rochester Medical Center. University of Iowa Stead Family Department of Pediatrics. United States Early Human DevelopmentEarly Hum Dev 2025; DOI: 10.1016/j.earlhumdev.2025.106342 AbstractObjective: To determine if pulmonary hypertension (PH) screening in at-risk infants born preterm reduces morbidity and/or NICU length of stay.Study design: This single-center retrospective cohort chart

The effectiveness of pulmonary hypertension screening in infants born preterm Read More »

Scroll to Top