Class 3. Pulmonary Hypertension Associated with Lung Disease

Sodium nitrite prevents impaired postnatal alveolar development

Kathrine L. Daniel, Chantal Gaudet, Ali Hamraghani, Nadya Ben Fadel, Behzad Yeganeh, Robert P. JankovChildren’s Hospital of Eastern Ontario Research Institute. University of Ottawa.Canada American Journal of Physiology Lung Cellular and Molecular PhysiologyAm J Physiol Lung Cell Mol Physiol 2025; DOI: 10.1152/ajplung.00324.2024 AbstractDeficient nitric oxide (NO) signaling plays a critical role in the pathogenesis of bronchopulmonary […]

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Prevalence and outcomes of air leak syndrome and subtypes in neonates in the United States

Adam Beaton, Prithvi Sendi, Paul A. Martinez, Balagangadhar R. TotapallyCohen Children’s Medical Center. Nicklaus Children’s Hospital. Florida International University. United States Journal of Neonatal-Perinatal MedicineJ Neonatal Perinatal Med 2025; 17: 846-857DOI: 10.1177/19345798241308491 AbstractObjectives: To describe the prevalence, risk factors, and outcomes for neonatal air leak syndrome and its subtypes (pneumothorax, pneumomediastinum, pneumopericardium, pulmonary interstitial emphysema, and pneumoperitoneum), evaluate variables associated with the development

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Growing Up with Developmental Lung Diseases: A Review for the Adult Pulmonologist

Yadira Rivera-Sanchez, Zachary W. Blair, Tyler J. Wall, Kara N. GossUniversity of Texas Southwestern Medical Center.United States ChestChest 2025; DOI: 10.1016/j.chest.2025.02.014 AbstractTopic importance: Improved childhood management strategies have decreased the early life morbidity and mortality of severe developmental lung disorders, such that an increasing number of individuals ultimately transition care to adult pulmonologists for management. Alternatively, individuals

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Characteristics associated with death or tracheostomy in infants with bronchopulmonary dysplasia following predominant non-invasive respiratory support

Heidi Morris, Megan Reilly, Huayan Zhang, Xiaoyue Dong, Kathleen Gibbs, Catherine M. Avitabile, Sara B. DeMauro, Nicolas A. BamatChildren’s Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine. Guangzhou Women and Children’s Medical Center.United States and China Journal of PerinatologyJ Perinatol 2025; DOI: 10.1038/s41372-025-02234-z AbstractObjective: Identify characteristics associated with death or tracheostomy (D/T) in preterm infants with bronchopulmonary dysplasia (BPD)

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Developing a Neonatal Pulmonary Hypertension Core Outcome Set (NeoPH COS)-A Study Protocol

Cara Ellen Morgan, Kerry Woolfall, Natasharazia Aikman, Crhistopher Gale, Nimish Subhedar, the RePHyNeConsortiumLiverpool Women’s NHS Trust and Univeristy of Liverppool. Imperial College London.United Kingdom Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70052 AbstractPulmonary hypertension (PH) in newborn babies is a relatively rare, heterogeneous condition that has high associated mortality in the neonatal period and beyond. There are

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Inhaled Epoprostenol in Children With Pediatric Acute Respiratory Distress Syndrome: A Single-Center Retrospective Study

Eleanor J. Scalone, Alan G. Woodruff, Amit K. Saha, John M. Wright, Kristopher L. Dixon, Andora L. Bass, Michael J. Walsh, Michael C. McCroryWake Forest University School of Medicine. University of Pennsylvania Perelman School of Medicine.United States Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.71010 AbstractBackground: Inhaled epoprostenol (iEpo) may improve oxygenation in adults with hypoxic respiratory failure,

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Modifiable and Non-Modifiable Risk Factors for Tracheostomy in Preterm Infants

Brandon Dudeck, Elias W. Abebe, Wendy Sun, Peter R. Gaskin, Rose M. Viscardi, Eunsung ChoUniversity of Maryland School of Medicine. Wellspan York Hospital. Los Angeles Mattel Children’s Hospital and University of California, Los Angeles.United States Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.71005 AbstractObjective: To identify risk factors for tracheostomy among infants born < 33 week gestational age.Methods: We

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Risk Factors Associated With the Development of Late Pulmonary Artery Hypertension in Extremely Premature Infants

Paige E. Condit, JohnS. Hokanson Vivek Balasubramaniam, David J. McCulley, Michael Lasarev, Luke Lamers, Ryan M. McAdams, Dinushan C. KaluarachchiUniversity of Wisconsin School of Medicine and Public Health. University of California, San Diego. United States Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.27501 AbstractObjective: To identify risk factors for late pulmonary artery hypertension (PH) at 36 weeks’ postmenstrual

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Detection of pulmonary hypertension in preterm infants with bronchopulmonary dysplasia using oxygen saturation data

Pravitha Ramanand, Premananda Indic, Samuel J. Gentle, Namasivayam AmbalavananUniversity of Texas at Tyler. University of Alabama at Birmingham.United States Pediatric ResearchPediatr Res 2025; DOI: 10.1038/s41390-025-03891-8 AbstractBackground: Pulmonary hypertension (PH) complicates the clinical course of bronchopulmonary dysplasia (BPD) in preterm infants, increasing risk of mortality and other morbidities. Early detection of PH may provide the clinical opportunity for

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Celastrol has beneficial effects on pulmonary hypertension associated with bronchopulmonary dysplasia: Preclinical study outcomes

Claire-Marie Pilard, Guillaume Cardouat, Isabel Gauthereau, Laure Gassiat, Mathilde Dubois, Paul Robillard, Fanny Sauvestre, Fanny Pelluard, Sophie Berenguer, Melie Sarreau, Stéphane Claverol, Caroline Tokarski, Loïc Sentilhes, Frederic Coatleven, Marie Vincienne, Roger Marthan, Eric Dumas-de-la-Roque, Patrick Berger, Mark K. Friedberg, Laurent Renesme, Véronique Freund-Michel, Christelle GuibertUniversity of Bordeaux and Bordeaux University Hospital. Hospital for Sick Children

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