Class 3. Pulmonary Hypertension Associated with Lung Disease

Characteristics and outcomes of preterm infants with early pulmonary hypertension

Rachel Mullaly, Aisling Smith, Claire Murphy, Seán Armstrong, Orla Franklin, Naomi McCallion, Afif EL-KhuffashRotunda Hospital. Royal College of Surgeons in Ireland. Children’s Health Ireland at Crumlin.Ireland Journal of PerinatologyJ Perinatol 2025; DOI: 10.1038/s41372-025-02295-0 AbstractObjective: This study investigates incidence, outcomes and echocardiographic characteristics of preterm infants with early pulmonary hypertension (PH) compared to those without.Study design: A prospective observational […]

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Neurodevelopmental outcomes at age 5 years among children born very preterm and surviving after persistent pulmonary hypertension of the newborn: EPIPAGE-2 cohort study

Sophie Breinig, Virginie Ehlinger, Jean-Christophe Rozé, Laurent Storme, Xavier Durrmeyer, Gilles Cambonie, Lionel Berthomieu, Valérie Benhammou, Geraldine Gascoin, Pierre-Yves Ancel, Catherine ArnaudChildren’s Hospital, Toulouse University Hospital and Toulouse University. Nantes University Hospital. Lille University Hospital. CHI Créteil. Montpellier University Hospital. France European Journal of Paediatric NeurologyEur J Paediatr Neurol 2025; 55: 103-110DOI: 10.1016/j.ejpn.2025.03.007 AbstractObjective: To determine whether

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Characteristics and sex differences in bronchopulmonary dysplasia-related pulmonary hypertension

Dansha Zhou, Ting Wang, Yuqin Chen, Yulin Zheng, Yingzhen Zhou, Mingxiang Zhang, Aofeng Liu, Biao Hu, Shuang Fu, Ruixian Wu, Wei Chen, Xiaoli Jiang, Zehui Ye, Yuan Shi, Zhou Fu, Jian WangFirst Affiliated Hospital of Guangzhou Medical University and Guangzhou Medical University. Children’s Hospital of Chongqing Medical University. China BioMedical Central Pulmonary MedicineBMC Pulm Med

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Mechanisms of hypoxaemia in late pulmonary hypertension associated with bronchopulmonary dysplasia

Eleanor Jeffreys, Fahad M. S. Arattu Thodika, Aaron Bell, Anne Greenough, Theodore DassiosKing’s College, King’s College Hospital and NHS Foundation Trust. Evelina Children’s Hospital, Guy’s and St Thomas’ NHS Foundation Trust. University of Patras.United Kingdom and Greece Journal of Perinatal MedicineJ Perinat Med 2025; DOI: 10.1515/jpm-2025-0058 AbstractAbstract Not Available CategoryClass III. Pulmonary Hypertension Associated with Lung

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Respiratory Support Strategies for Surgical Neonates: A Review

Piero Alberti, Niyi Ade-Ajayi, Anne GreenoughKing’s College London.United Kingdom ChildrenChildren 2025; 12: DOI: 10.3390/children12030273 AbstractNeonates with congenital conditions which require surgical management frequently experience respiratory distress. This review discusses the management of pulmonary complications and the respiratory support strategies for four conditions: oesophageal atresia-tracheoesophageal fistula (OA-TOF), congenital diaphragmatic hernia (CDH), congenital lung malformations (CLM), and anterior

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Intraamniotic Vitamin D Preserves Lung Development and Prevents Pulmonary Hypertension in Experimental Bronchopulmonary Dysplasia due to Intraamniotic sFlt-1

Michael W. Cookson, Tania Gonzalez, Elisa M. Bye, Greg Seedorf, Sarah Ellor, Brad J. Smith, James C. Fleet, Erica W. MandellUniversity of Colorado, Anschutz School of Medicine and Children’s Hospital Colorado. University of Texas.United States American Journal of Physiology Lung Cellular and Molecular PhysiologyAm J Physiol Lung Cell Mol Physiol 2025; DOI: 10.1152/ajplung.00409.2024 AbstractPreterm infants born

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Airway Anomalies Predict Risk of Pediatric Pulmonary Hypertension

Elana R. Kriegel, Aditya Srinivasen, Luke Mammen, Harini Venkataganesh, Jess T. Randall, Lara ReichertAlbany Medical College and Albany Medical Center.United States Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.71028 AbstractIntroduction: Pediatric pulmonary hypertension (PH) significantly contributes to morbidity and mortality due to the progressive nature of the disease in some subtypes, which leads to severe right heart failure,

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Right Atrial Dysfunction Is Prevalent in Pediatric Acute Respiratory Distress Syndrome and Reflects Pulmonary Hypertension and Right Ventricular Dysfunction

Nathan D. Markiewitz, Yan Wang, Robert A. Berg, Nadir Yehya, Celeste Dixon, Laura Mercer-Rosa, Adam S. HimebauchChildren’s Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania. United States Critical Care ExplorationsCrit Care Exp 2025; 7: DOI: 10.1097/CCE.0000000000001230 AbstractImportance: Right atrial (RA) dysfunction is associated with worse outcomes in some populations with pulmonary hypertension

Right Atrial Dysfunction Is Prevalent in Pediatric Acute Respiratory Distress Syndrome and Reflects Pulmonary Hypertension and Right Ventricular Dysfunction Read More »

A maternal hypoxia mouse model to study the effect of late gestational hypoxia on offspring lung outcomes

Thi-Tina N. Nguyen, Caitlin V. Lewis, Daniel Colon Hidalgo, Janelle N. Posey, Mariah Jordan, Timothy E. Porfilio, Maya R. Grayck, Clyde J. Wright, Cassidy Delaney, Eva S. NozikUniversity of Colorado Anschutz Medical Campus. United States Frontiers in PhysiologyFront Physiol 2025; 16: DOI: 10.3389/fphys.2025.1513703 AbstractExtremely preterm birth predisposes infants to bronchopulmonary dysplasia and associated pulmonary hypertension (PH).

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Differences in Pulmonary Artery Stiffness Measured by CMR in Preterm-Born Young Adults With and Without Bronchopulmonary Dysplasia

Wouter J. van Genuchten, Jarno J. Steenhorst, Gabrielle M. J. W. van Tussenbroek, Nikki van der Velde, Lieke S. Kamphuis, Irwin K. M. Reiss, Daphne Merkus, Willem A. Helbing, Alexander HirschErasmus MC. University Hospital Munich.Netherlands and Germany Circulation Cardiovascular ImagingCirc Cardiovasc Imaging 2025; DOI: 10.1161/CIRCIMAGING.124.017791 AbstractBackground: Very preterm-born infants are at risk for developing bronchopulmonary dysplasia (BPD), a chronic lung disease. Nowadays, the majority of these infants reach adulthood.

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