Class 3. Pulmonary Hypertension Associated with Lung Disease

Variability in Home Oxygen Therapy Practices for Bronchopulmonary Dysplasia in Japan: A Questionnaire Survey

Ryo Ogawa, Masaki Hasebe, Tomohiko Nakamura, Fumihiko NambaNagano Children’s Hospital. Saitama Medical Center and Saitama Medical University.Japan Journal of Paediatrics and Child HealthJ Paediatr Child Health 2025; DOI: 10.1111/jpc.70150 AbstractAim: To examine variations in home oxygen therapy (HOT) initiation and management practices for bronchopulmonary dysplasia (BPD) among perinatal medical centres in Japan.Methods: A questionnaire survey was distributed to

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Allergy and atopic phenotype are associated with earlier gestation and severity of respiratory symptoms in bronchopulmonary dysplasia

Brianna C. Aoyama, Joseph M. Collaco, Amit Agarwal, Gangaram Akangire, Eric D. Austin, Manvi Bansal, Anita Bhandari, A. Ioana Critea, Lystra P. Hayden, Jonathan C. Levin, Winston M. Manimtim, Audrey N. Miller, Paul E. Moore, Antonia P. Popova, Lawrence M. Rhein, Catherine A. Sheils, Steven H. Abman, Christopher D. Baker, Sara K. Dawson, Mehtap Haktanir

Allergy and atopic phenotype are associated with earlier gestation and severity of respiratory symptoms in bronchopulmonary dysplasia Read More »

Prematurity and obstructive sleep apnea in children: The perfect storm

Oscar Camilo Pantoja-Gomez, Juanita Agudelo-Agudelo, Elida Duenas-Meza, Sonia M. Restrepo-Gualteros, Maria J. Gutierrez, Gustavo NinoUniversidad de La Sabana. Universidad Nacional de Colombia. Johns Hopkins University. Children’s National Hospital and George Washington University School of Medicine and Health Sciences.Columbia and United States Paediatric Respiratory ReviewsPaediatr Respir Rev 2025; DOI: 10.1016/j.prrv.2025.06.001 AbstractAs survival rates for premature infants improve,

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Critical Care Dilemma: Complex Congenital Pulmonary Airway Malformation With Pulmonary Hypertension in a Neonate

Sajjad M. AlKadhem, Ali T. Alattas, Hadeel AlJubab, Abdulwahhab S. AlJubabKing Fahad Medical City.Saudi Arabia CureusCureus 2025; 17: DOI: 10.7759/cureus.85279 AbstractCongenital pulmonary airway malformations (CPAMs) are the most prevalent congenital lung lesions, yet their postnatal trajectory remains heterogeneous. Although many antenatally detected macrocystic lesions remain clinically silent, rapid postnatal enlargement can precipitate tension physiology, air-leak syndromes,

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Development of late pulmonary hypertension after antenatal inflammation in experimental bronchopulmonary dysplasia

Paula Dias Maia, Gregory Seedorf, Tania Gonzalez, Elisa Bye, Benjamin S. Frank, Erica W. Mandell, Steven H. AbmanUniversity of Colorado Anschutz School of Medicine and Children’s Hospital Colorado. Unoted States Pediatric ResearchPediatr Res 2025; DOI: 10.1038/s41390-025-04223-6 AbstractBackground: Antenatal inflammation due to chorioamnionitis is strongly associated with the development of bronchopulmonary dysplasia (BPD) and BPD-associated pulmonary hypertension (BPD-PH)

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Oxygen Saturation Targeting in the Neonatal Intensive Care Unit

Faeq Almudares, Bheru Gandhi, Jonathan Davies, Xanthi Couroucli, Natalie Villafranco, Nidhy Paulose Varghese, Milenka Cuevas Guaman, Charleta Guillory, Binoy ShivannaBaylor College of Medicine.United States Journal of Clinical MedicineJ Clin Med 2025; 14: DOI: 10.3390/jcm14113975 AbstractOxygen (O2) is vital for cellular development, function, proliferation, and repair, underscoring its critical role in organogenesis. Both hypoxia (reduced tissue O2)

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Bronchopulmonary dysplasia with pulmonary hypertension associates with semaphorin signaling loss and functionally decreased FOXF1 expression

Shawyon P. Shirazi, Nicholas M. Negretti, Christopher S. Jetter, Alexandria L. Sharkey, Shriya Garg, Meghan E. Kapp, Devan Wilkins, Gabrielle Fortier, Saahithi Mallapragada, Nicholas E. Banovich, Laurie C. Eldredge, Gail H. Deutsch, Christopher V. E. Wright, David B. Frank, Jonathan A. Kropski, Jennifer M. S. SucreVanderbilt University Medical Center and Vanderbilt University. Translational Genomics Research

Bronchopulmonary dysplasia with pulmonary hypertension associates with semaphorin signaling loss and functionally decreased FOXF1 expression Read More »

Sex differences in the risk of bronchopulmonary dysplasia and pulmonary hypertension: a Bayesian meta-analysis

Elke Van Westering-Kroon, Tamara M. Hundscheid, Karen Van Mechelen, Frantisek Bartos, Steven H. Abman, Eduardo VillamorMosaKids Children’s Hospital, Maastricht University Medical Centre and Maastricht University. University of Amsterdam. University of Colorado Anschutz School of Medicine and Children’s Hospital Colorado. Netherlands and United States Pediatric ResearchPediatr Res 2025; DOI: 10.1038/s41390-025-04145-3 AbstractBackground: Bronchopulmonary dysplasia (BPD) is generally considered to

Sex differences in the risk of bronchopulmonary dysplasia and pulmonary hypertension: a Bayesian meta-analysis Read More »

Pulmonary arteriole narrowing in end-stage cystic fibrosis lungs occurs with and without small airway disease

Astrid Vermaut, Gitte Aerts, Lynn Willems, Vincent Geudens, Charlotte Hooft, Pieterjan Kerckhof, Lise Vanvuchelen, Marta Zapata-Ortega, Hanne Beeckmans, Xin Jin, Yousry Mohamady, Jan Van Slambrouck, Lucia Aversa, Janne Verhaegen, Emanuela E. Cortesi, Charlotte De Fays, Birgit Weynand,Dirk E. Van Raemdonck, Laurens J. Ceulemans, Wim A. Wuyts, Marianne Carlon, Robin Vos, Natalie Lorent, Ghislaine Gayan-Ramirez, Laurent

Pulmonary arteriole narrowing in end-stage cystic fibrosis lungs occurs with and without small airway disease Read More »

Deficiency of arginase2 attenuates hyperoxia-induced inflammation and airway hyperreactivity in neonatal mice

Yi Jin, Bernadette Chen, Yusen Liu, Leif D. NelinNationwide Children’s Hospital and Ohio State University.United States American Journal of Physiology Lung Cellular and Molecular PhysiologyAm J Physiol Lung Cell Mol Physiol 2025; DOI: 10.1152/ajplung.00202.2024 AbstractBronchopulmonary dysplasia (BPD) is a common chronic lung disease in pediatrics. Neonatal mice placed in hyperoxia (85% oxygen, HYP) develop lung injury

Deficiency of arginase2 attenuates hyperoxia-induced inflammation and airway hyperreactivity in neonatal mice Read More »

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