Class 3. Pulmonary Hypertension Associated with Lung Disease

Clinical Characteristics and Outcomes for Neonates with Respiratory Failure Referred for Extracorporeal Membrane Oxygenator (ECMO) Support

Pooja Musuku, Keith Meyer, Felipe E. Pedroso, Fuad Alkhoury, Balagangadhar R. TotapallyNicklaus Children’s Hospital. Herbert Wertheim College of Medicine and Florida International University.United States ChildrenChildren 2025; 12: DOI: 10.3390/children12070925 AbstractObjective: The aim of this study was to describe the presenting characteristics and outcomes of neonates with respiratory failure referred for extracorporeal membrane oxygenation (ECMO) support, compare […]

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Impact of Pulmonary Hypertension and Patent Ductus Arteriosus in Preterm Infants with Presumed Pulmonary Hypoplasia

Sol Kim, Yumi Seo, Moon-Yeon Oh, Min Soo Kim, Sook Kyung YumSeoul St. Mary’s Hospital and Catholic University of Korea.Republic of Korea BiomedicinesBiomedicines 2025; 13: DOI: 10.3390/biomedicines13071725 AbstractObjectives: Pulmonary hypertension and hemodynamically significant PDA (hsPDA) involve seemingly opposite physiological features-decreased pulmonary blood flow and pulmonary overcirculation, respectively-but the literature demonstrates variable respiratory consequences in association with

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Outcomes of extremely preterm infants with bronchopulmonary dysplasia: a retrospective cohort study

Ashraf Gad, Rowan Mesilhy, Thomas Maveli, FatimaAli, Noora Jasim, MalazAdam, Tasneim Abdalla, Mohamed Madani, Mohammad Ayman Alkhateeb, Mohammad A. A. BayoumiHamad Medical Corporation. Qatar University. Sidra Medicine. Qatar Scientific ReportsSci Rep 2025; 15: DOI: 10.1038/s41598-025-12066-8 AbstractTo investigate the respiratory and related health outcomes at 18 months for extremely preterm (EP) infants diagnosed with bronchopulmonary dysplasia (BPD).

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The effectiveness of pulmonary hypertension screening in infants born preterm

Stephanie Vachon, Rajiv Devanagondi, Andrew Dylag, Hongyue Wang, Gloria PryhuberUniversity of Rochester Medical Center. University of Iowa Stead Family Department of Pediatrics. United States Early Human DevelopmentEarly Hum Dev 2025; DOI: 10.1016/j.earlhumdev.2025.106342 AbstractObjective: To determine if pulmonary hypertension (PH) screening in at-risk infants born preterm reduces morbidity and/or NICU length of stay.Study design: This single-center retrospective cohort chart

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Variability in Home Oxygen Therapy Practices for Bronchopulmonary Dysplasia in Japan: A Questionnaire Survey

Ryo Ogawa, Masaki Hasebe, Tomohiko Nakamura, Fumihiko NambaNagano Children’s Hospital. Saitama Medical Center and Saitama Medical University.Japan Journal of Paediatrics and Child HealthJ Paediatr Child Health 2025; DOI: 10.1111/jpc.70150 AbstractAim: To examine variations in home oxygen therapy (HOT) initiation and management practices for bronchopulmonary dysplasia (BPD) among perinatal medical centres in Japan.Methods: A questionnaire survey was distributed to

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Allergy and atopic phenotype are associated with earlier gestation and severity of respiratory symptoms in bronchopulmonary dysplasia

Brianna C. Aoyama, Joseph M. Collaco, Amit Agarwal, Gangaram Akangire, Eric D. Austin, Manvi Bansal, Anita Bhandari, A. Ioana Critea, Lystra P. Hayden, Jonathan C. Levin, Winston M. Manimtim, Audrey N. Miller, Paul E. Moore, Antonia P. Popova, Lawrence M. Rhein, Catherine A. Sheils, Steven H. Abman, Christopher D. Baker, Sara K. Dawson, Mehtap Haktanir

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Prematurity and obstructive sleep apnea in children: The perfect storm

Oscar Camilo Pantoja-Gomez, Juanita Agudelo-Agudelo, Elida Duenas-Meza, Sonia M. Restrepo-Gualteros, Maria J. Gutierrez, Gustavo NinoUniversidad de La Sabana. Universidad Nacional de Colombia. Johns Hopkins University. Children’s National Hospital and George Washington University School of Medicine and Health Sciences.Columbia and United States Paediatric Respiratory ReviewsPaediatr Respir Rev 2025; DOI: 10.1016/j.prrv.2025.06.001 AbstractAs survival rates for premature infants improve,

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Critical Care Dilemma: Complex Congenital Pulmonary Airway Malformation With Pulmonary Hypertension in a Neonate

Sajjad M. AlKadhem, Ali T. Alattas, Hadeel AlJubab, Abdulwahhab S. AlJubabKing Fahad Medical City.Saudi Arabia CureusCureus 2025; 17: DOI: 10.7759/cureus.85279 AbstractCongenital pulmonary airway malformations (CPAMs) are the most prevalent congenital lung lesions, yet their postnatal trajectory remains heterogeneous. Although many antenatally detected macrocystic lesions remain clinically silent, rapid postnatal enlargement can precipitate tension physiology, air-leak syndromes,

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Development of late pulmonary hypertension after antenatal inflammation in experimental bronchopulmonary dysplasia

Paula Dias Maia, Gregory Seedorf, Tania Gonzalez, Elisa Bye, Benjamin S. Frank, Erica W. Mandell, Steven H. AbmanUniversity of Colorado Anschutz School of Medicine and Children’s Hospital Colorado. Unoted States Pediatric ResearchPediatr Res 2025; DOI: 10.1038/s41390-025-04223-6 AbstractBackground: Antenatal inflammation due to chorioamnionitis is strongly associated with the development of bronchopulmonary dysplasia (BPD) and BPD-associated pulmonary hypertension (BPD-PH)

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Oxygen Saturation Targeting in the Neonatal Intensive Care Unit

Faeq Almudares, Bheru Gandhi, Jonathan Davies, Xanthi Couroucli, Natalie Villafranco, Nidhy Paulose Varghese, Milenka Cuevas Guaman, Charleta Guillory, Binoy ShivannaBaylor College of Medicine.United States Journal of Clinical MedicineJ Clin Med 2025; 14: DOI: 10.3390/jcm14113975 AbstractOxygen (O2) is vital for cellular development, function, proliferation, and repair, underscoring its critical role in organogenesis. Both hypoxia (reduced tissue O2)

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