Class 1. Pulmonary Hypertension Associated with Inflammation

NLRP3 Inflammasome Triggers Inflammation of Obstructive Sleep Apnea

Xiaoting Yangzhong, Shu Hua, Yiqiong Wen, Xiaoqing Bi, Min Li, Yuanyuan Zheng, Shibo SunFirst Affiliated Hospital, Kunming Medical University.China Current Molecular MedicineCurr Mol Med 2024; DOI: 10.2174/0115665240294605240426123650 AbstractObstructive sleep apnea [OSA] is widespread in the population and affects as many as one billion people worldwide. OSA is associated with dysfunction of the brain system that controls […]

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Fatal pulmonary arterial hypertension (PAH): A rare association of anti-MDA-5 positive juvenile dermatomyositis

R. Shreyas, Anagha Patteri, M. B. Hayagrivas, Tanya Singla, Shivaprasad Pannasamudra Mohankumar, Saurabh Kumar Gupta, Manisha Jana, Narendra Kumar Bagri, A. V. RamananAll India Institute of Medical Sciences. Bristol Royal Hospital for Children.India and United Kingdom International Journal of Rheumatic DiseasesInt J Rheum Dis 2024; 27: DOI: 10.1111/1756-185X.15180 AbstractAbstract Not Available CategoryClass I. Pulmonary Hypertension Associated

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Single cell transcriptomic analyses reveal diverse and dynamic changes of distinct populations of lung interstitial macrophages in hypoxia-induced pulmonary hypertension

Sushil Kumar, Claudia Mickael, Rahul Kumar, Ram Raj Prasad, Nzali V. Campbell, Hui Zhang, Min Li, B. Alexandre McKeon, Thaddeus E. Allen, Brian B. Graham, Yen-Rei A. Yu, Kurt R. StenmarkUniversity of Colorado School of Medicine. University of California San Francisco. Zuckerberg San Francisco General Hospital.United States Frontiers in ImmunologyFront Immunol 2024; 15: DOI: 10.3389/fimmu.2024.1372959 AbstractIntroduction: Hypoxia

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Cardiovascular risk and inflammation in a population with autoimmune diseases: a narrative review

Camilla Bertoni, Alessandra Mazzocchi, Ludovica Leone, Carlo Agostoni, Giovanni FilocamoUniversity of Milan. Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca’ Grande Ospedale Maggiore Policlinico. Italy Frontiers in ImmunologyFront Immunol 2024; 15:DOI: 10.3389/fimmu.2024.1380372 AbstractJuvenile Systemic Connective Tissue Diseases (JSCTD) are a heterogeneous group of chronic autoimmune diseases, associated with dyslipidemia and increased cardiovascular risk

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c-Myc Drives inflammation of the maternal-fetal interface, and neonatal lung remodeling induced by intra-amniotic inflammation

April W. Tan, Xiaoying Tong, Silvia Alvarez-Cubela, Pingping Chen, Aline Guimarães Santana, Alejo A. Morales, Runxia Tian, Rae Infante, Vanessa Nunes de Paiva, Shathiyah Kulandavelu, Merline Benny, Juan Dominguez-Bendala, Shu Wu, Karen C. Young, Claudia O. Rodrigues, Augusto F. SchmidtUniversity of Miami Miller School of Medicine and Holtz Children’s Hospital. Florida Atlantic University Charles E.

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Leukotriene B4 levels in CHD-associated paediatric pulmonary hypertension

Gamze Vuran, Murat Muhtar Yilmazer, Engin Gerceker, Cüneyt Zihni, Timur MeseUniversity of Health Sciences and İzmir Dr. Behçet Uz Pediatric Diseases and Surgery Training and Research Hospital.Turkey Cardiology in the YoungCardiol Young 2024;DOI: 10.1017/S1047951124000362 AbstractBackground: The aim of this study is to evaluate the role of leukotriene B4, an inflammatory mediator, in the development of pulmonary hypertension

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Long-term outcomes and immune profiling in children with multisystem inflammatory syndrome (MIS-C)

Indira Jaxybayeva, Riza Boranbayeva, Minira Bulegenova, Natalya Urazalieva, Valentin Gerein, Lyazat ManzhuovaAsfendiyarov Kazakh National Medical University. Goethe University Hospital.Kazakhstan and Germany Acta BiomedicaActa Biomed 2023;DOI: 10.23750/abm.v94i6.14788 AbstractBackground and aim: Existing follow-up data after MIS-C is limited.Purpose of the study: to investigate the long-term consequences in children who have undergone MIS-C.Methods: The retrospective study included 93 children. The identified changes

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Single-Cell Imaging Maps Inflammatory Cell Subsets to Pulmonary Arterial Hypertension Vasculopathy

Selena Ferrian, Aiqin Cao, Erin McCaffrey, Toshie Saito, Noah F. Greenwald, Mark R. Nichols, Trevor Bruce, Roham T. Zamanian, Patricia Del Rosario, Marlene Rabinovitch, Michael AngeloStanford University School of Medicine. United States American Journal of Respiratory and Critical Care MedicineAm J Respir Crit Care Med 2023; DOI: 10.1164/rccm.202209-1761OC AbstractRationale: Elucidating the immune landscape within and surrounding pulmonary

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A very rare cause of pre-capillary pulmonary hypertension: The PAMI syndrome

Manuela Iseppi, Giulio Savonitto, Alberto Tommasini, Alessia Pin, Gianfranco Sinagra, Davide Stolfozienda Sanitaria Universitaria Giuliano-Isontina (ASUGI) and University of Trieste. University of Verona. Karolinska Institutet.Italy and Sweden Pulmonary CirculationPulm Circ 2023; 13: DOI: 10.1002/pul2.12300 AbstractWe report the first known case of PAMI syndrome associated with pulmonary arterial hypertension (PAH) with a positive response to cyclophosphamide and

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Identification of the shared gene signatures between pulmonary fibrosis and pulmonary hypertension using bioinformatics analysis

Hui Zhao, Lan Wang, Yi Yan, Qin-Hua Zhao, Jing He, Rong Jiang, Ci-Jun Luo, Hong-Ling Qiu, Yu-Qing Miao, Su-Gang Gong, Ping Yuan, Wen-Hui WuShanghai Pulmonary Hospital and Tongji University. University of Shanghai for Science and Technology. Shanghai Children’s Medical Center and Shanghai Jiao Tong University.China Frontiers in ImmunologyFront Immunol 2023; DOI: 10.3389/fimmu.2023.1197752 AbstractPulmonary fibrosis (PF) and

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