Class 1. Pulmonary Hypertension Associated with Inflammation

The role of immune cells in the pathogenesis of connective tissue diseases-associated pulmonary arterial hypertension

Zhe Li, Juan Ma, Xuejing Wang, Liquan Zhu, Yu Gan, Baoquan DaiWeifang Maternal and Child Health Hospital. Shandong Second Medical University.China Frontiers in ImmunologyFront Immunol 2024; 15: DOI: 10.3389/fimmu.2024.1464762 AbstractConnective tissue diseases-related pulmonary arterial hypertension (CTD-PAH) is a disease characterized by an elevated pulmonary artery pressure that arises as a complication of connective tissue diseases. The […]

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Lung EC-SOD Overexpression Prevents Hypoxia-Induced Platelet Activation and Lung Platelet Accumulation

Daniel Colon Hidalgo, Mariah Jordan, Janelle N. Posey, Samuel D. Burciaga, Thi-Tina N. Nguyen, Christina Sul, Caitlin V. Lewis 2, Cassidy Delaney, Eva S. NozikUniversity of Colorado Anschutz Medical Campus. United States AntioxidantsAntioxidants 2024; 13: DOI: 10.3390/antiox13080975 AbstractPulmonary hypertension (PH) is a progressive disease marked by pulmonary vascular remodeling and right ventricular failure. Inflammation and oxidative

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Multisystem Inflammatory Syndrome in Neonates Associated with COVID-19 in Neonatal ICU of a Tertiary Care Hospital

Asma Shabbir, Humaira Khurshid, Imran Mahmood KhanFazaia Medical College, Pakistan Air Force Hospital.Pakistan Journal of the College of Physicians and Surgeons PakistanJ Coll Physicians Surg Pak 2024; 34: 727-731 DOI: 10.29271/jcpsp.2024.06.727 AbstractObjective: Neonatal multisystem inflammatory syndrome (MIS-N) is a unique disease of neonates described in several case reports from all over the world with a myriad of

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Interstitial macrophage phenotypes in Schistosoma-induced pulmonary hypertension

Rahul Kumar, Sushil Kumar, Claudia Mickael, Dara Fonseca Balladares, Kevin Nolan, Michael H. Lee, Linda Sanders, Julia Nilsson, Ari B. Molofsky, Rubin M. Tuder, Kurt R. Stenmark, Brian B. GrahamUniversity of California, San Francisco and Zuckerberg San Francisco General Hospital. University of Colorado Anschutz Medical Campus. United States Frontiers in ImmunologyFront Immunol 2024; DOI: 10.3389/fimmu.2024.1372957 AbstractBackground: Schistosomiasis

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NLRP3 Inflammasome Triggers Inflammation of Obstructive Sleep Apnea

Xiaoting Yangzhong, Shu Hua, Yiqiong Wen, Xiaoqing Bi, Min Li, Yuanyuan Zheng, Shibo SunFirst Affiliated Hospital, Kunming Medical University.China Current Molecular MedicineCurr Mol Med 2024; DOI: 10.2174/0115665240294605240426123650 AbstractObstructive sleep apnea [OSA] is widespread in the population and affects as many as one billion people worldwide. OSA is associated with dysfunction of the brain system that controls

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Fatal pulmonary arterial hypertension (PAH): A rare association of anti-MDA-5 positive juvenile dermatomyositis

R. Shreyas, Anagha Patteri, M. B. Hayagrivas, Tanya Singla, Shivaprasad Pannasamudra Mohankumar, Saurabh Kumar Gupta, Manisha Jana, Narendra Kumar Bagri, A. V. RamananAll India Institute of Medical Sciences. Bristol Royal Hospital for Children.India and United Kingdom International Journal of Rheumatic DiseasesInt J Rheum Dis 2024; 27: DOI: 10.1111/1756-185X.15180 AbstractAbstract Not Available CategoryClass I. Pulmonary Hypertension Associated

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Single cell transcriptomic analyses reveal diverse and dynamic changes of distinct populations of lung interstitial macrophages in hypoxia-induced pulmonary hypertension

Sushil Kumar, Claudia Mickael, Rahul Kumar, Ram Raj Prasad, Nzali V. Campbell, Hui Zhang, Min Li, B. Alexandre McKeon, Thaddeus E. Allen, Brian B. Graham, Yen-Rei A. Yu, Kurt R. StenmarkUniversity of Colorado School of Medicine. University of California San Francisco. Zuckerberg San Francisco General Hospital.United States Frontiers in ImmunologyFront Immunol 2024; 15: DOI: 10.3389/fimmu.2024.1372959 AbstractIntroduction: Hypoxia

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Cardiovascular risk and inflammation in a population with autoimmune diseases: a narrative review

Camilla Bertoni, Alessandra Mazzocchi, Ludovica Leone, Carlo Agostoni, Giovanni FilocamoUniversity of Milan. Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca’ Grande Ospedale Maggiore Policlinico. Italy Frontiers in ImmunologyFront Immunol 2024; 15:DOI: 10.3389/fimmu.2024.1380372 AbstractJuvenile Systemic Connective Tissue Diseases (JSCTD) are a heterogeneous group of chronic autoimmune diseases, associated with dyslipidemia and increased cardiovascular risk

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c-Myc Drives inflammation of the maternal-fetal interface, and neonatal lung remodeling induced by intra-amniotic inflammation

April W. Tan, Xiaoying Tong, Silvia Alvarez-Cubela, Pingping Chen, Aline Guimarães Santana, Alejo A. Morales, Runxia Tian, Rae Infante, Vanessa Nunes de Paiva, Shathiyah Kulandavelu, Merline Benny, Juan Dominguez-Bendala, Shu Wu, Karen C. Young, Claudia O. Rodrigues, Augusto F. SchmidtUniversity of Miami Miller School of Medicine and Holtz Children’s Hospital. Florida Atlantic University Charles E.

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Leukotriene B4 levels in CHD-associated paediatric pulmonary hypertension

Gamze Vuran, Murat Muhtar Yilmazer, Engin Gerceker, Cüneyt Zihni, Timur MeseUniversity of Health Sciences and İzmir Dr. Behçet Uz Pediatric Diseases and Surgery Training and Research Hospital.Turkey Cardiology in the YoungCardiol Young 2024;DOI: 10.1017/S1047951124000362 AbstractBackground: The aim of this study is to evaluate the role of leukotriene B4, an inflammatory mediator, in the development of pulmonary hypertension

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