Class 1. Persistent Pulmonary Hypertension of the Newborn

Pulmonary Vascular Regulation in the Fetal and Transitional Lung

Hannah Holmes, Brahmdeep S. Saini, Olivia J. Moir, Jack R. T. Darby, Janna L. Morrison, Liqun Sun, Mike SeedHospital for Sick Children and University of Toronto. University of South Australia. Canada and Australia Clinics in PerinatologyClin Perinatol 2024; 51: 1-19DOI: 10.1016/j.clp.2023.11.003 AbstractFetal lungs have fewer and smaller arteries with higher pulmonary vascular resistance (PVR) than a […]

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Guidelines and Recommendations for Targeted Neonatal Echocardiography and Cardiac Point-of-Care Ultrasound in the Neonatal Intensive Care Unit: An Update from the American Society of Echocardiography

Patrick J. McNamara, Amish Jain, Afif El-Khuffash, Regan Giesinger, Dany Weisz, Lindsey Freud, Philip T. Levy, Shazia Bhombal, Willemde Boode, Tina Leone, Bernadette Richards, Yogen Singh, Jennifer M. Acevedo, John Simpson, Shahab Noori, Wyman W. LaiUniversity of Iowa. University of Toronto. Royal College of Surgeons in Ireland. Boston Children’s Hospital and Harvard Medical School. Emory

Guidelines and Recommendations for Targeted Neonatal Echocardiography and Cardiac Point-of-Care Ultrasound in the Neonatal Intensive Care Unit: An Update from the American Society of Echocardiography Read More »

Challenges in clinical identification of right ventricular dysfunction in preterm infants with persistent pulmonary hypertension of the newborn

Faith Zhua, Caio Barbosa de Oliveira, Nada Mohsen, Ashraf Kharrat, Poorva Deshpande, Luc Mertens, Amish JainMount Sinai Hospital, Hospital for Sick Children and University of Toronto.Canada Early Human DevelopmentEarly Hum Dev 2024; 190DOI: 10.1016/j.earlhumdev.2024.105942 AbstractBackground: Right ventricular dysfunction, typically qualitatively diagnosed (Q-RVd) in preterm infants, requires echocardiography which is not always acutely available. We aimed to identify

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Short term effect of intravenous treprostinil in term and preterm infants with pulmonary hypertension

Yoo-Jin Kim, Seung Han Shin, Ee-Kyung Kim, Han-Suk KimChung-buk National University Hospital. Seoul National University College of Medicine. Seoul National University Children’s Hospital. Republic of Korea BioMed Central PediatricsBMC Pediatr 2024; 23:DOI: 10.1186/s12887-023-04501-4 AbstractBackground: Pulmonary hypertension (PH) is a life-threatening condition in newborns. We aimed to assess the clinical and echocardiographic responses of term and preterm infants

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Case Report: Stüve-Wiedemann syndrome-a rare cause of persistent pulmonary hypertension of the newborn

Jessica Jin, Paula Rothämel, Johanna Büchel, Birgit Kammer, Theresa Brunet, Joseph Pattathu, Andreas W. Flemmer, Claudia Nussbaum, Sebastian SchroepfDr. von Hauner Children’s Hospital, University Hospital and Ludwig-Maximilians-Universität. University Hospital and Technical University of Munich. Germany Frontiers in PediatricsFront Pediatr 2024;DOI: 10.3389/fped.2023.1329404 AbstractIntroduction: Persistent pulmonary hypertension of the newborn (PPHN) is a life-threatening condition characterized by hypoxemia due

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Vasopressin in newborns with refractory acute pulmonary hypertension

Simon Ouellet, Christine Drolet, Genevéve Morissette, Annie Pellerin, Audrey HébertCHU de Québec, Université Laval. Canada Pediatric ResearchPediatr Res 2024;DOI: 10.1038/s41390-023-02995-3 AbstractBackground: Acute pulmonary hypertension (aPH) in newborns can be life threatening and challenging to manage. In newborns with refractory aPH, there is currently limited therapeutic agents.Methods: Retrospective single-center cohort study in newborns less than one month old who

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Epidemiology of neonatal pneumothorax developed spontaneously and during respiratory supports in neonatal intensive care units

N. Y. Boo, E. L. Lee Ang, The Malaysian National Neonatal RegistryUniversiti Tunku Abdul Rahman. Tengku Ampuan Rahimah Hospital.Malaysia Malaysian Journal of PathologyMalays J Pathol 2023; 45: 441-456DOI: Not Available AbstractBackground: Information on incidence and risk factors associated with different types of neonatal pneumothorax were lacking globally.Objectives: To determine incidences of pneumothorax developed spontaneously and during different

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Maternal treatment with selective serotonin reuptake inhibitors during pregnancy and delayed neonatal adaptation: a population-based cohort study

Marie-Coralie Cornet, Yvonne W. Wu, Heather Forquer, Lyndsay A. Avalos, Achyuth Sriram, Aaron W. Scheffler, Thomas B. Newman, Michael W. KuzniewiczUniversity of California San Francisco. Kaiser Permanente Northern California.United States Archives of Disease in Children Fetal and Neonatal EditionArch Dis Child Fetal Neonatal Ed 2023; DOI: 10.1136/archdischild-2023-326049 AbstractObjective: Selective serotonin reuptake inhibitor (SSRI) use is common in

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Shape of Pulmonary Artery Doppler Flow Profile and Right Ventricular Hemodynamics in Neonates

Sébastien Joye, Soume Bhattacharya, Ashraf Kharrat, Bonny Jasani, Regan E. Giesinger, Patrick J. McNamara, Amish JainLausanne University Hospital. LHSC Children’s Hospital. Mount Sinai Hospital and University of Toronto. Hospital of Sick Children. University of Iowa. Switzerland, Canada and United States Journal of PediatricsJ Pediatr 2023; DOI: 10.1016/j.jpeds.2023.113864 AbstractObjectives: To characterize pulmonary artery Doppler flow profile (PAFP) patterns

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Neonatal sepsis and cardiovascular dysfunction I: mechanisms and pathophysiology

Sophie M. Duignan, Satyan Lakshminrusimha, Kathryn Armstrong, Willem P. de Boode, Afif El-Khuffash, Orla Franklin, Eleanor J. Molloy, Infection, Inflammation, Immunology and Immunisation Section of the European Society for Pediatric Research (ESPR)Children’s Health Ireland at Crumlin. University of California, Davis Children’s Hospital. British Columbia Children’s Hospital. Radboud University Medical Center and Amalia Children’s Hospital. Royal

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