Class 1. Persistent Pulmonary Hypertension of the Newborn

Vardenafil vs. Sildenafil for the Treatment of Persistent Pulmonary Hypertension in Newborns

Sania El-HindiChildren’s Hospital.Syria Indian Journal of PediatricsIndian L Pediatr 2025; DOI: 10.1007/s12098-025-05787-1 AbstractAbstract Not Available CategoryClass I. Persistent Pulmonary Hypertension of the NewbornMedical Therapy. Efficacy or Lack of Efficacy Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication Article Access Free PDF File or Full Text Article […]

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Neonatal early-onset sepsis caused by Streptococcus Gallolyticus subsp. Pasteurianus with severe pulmonary hypertension and leukemoid reaction: a case report

Xuelian Wang, Ling Wang, Yuan Yuan, Xiaopeng Zhao, Huayan ZhangGuangzhou Women and Children’s Medical Center and Guangzhou Medical University. Children’s Hospital of Philadelphia.China and United States BioMedical Central PediatricsBMC Pediatr 2025; 25: DOI: 10.1186/s12887-025-06026-4 AbstractBackground: Streptococcus gallolyticus subsp. pasteurianus (SGSP) is an uncommon cause of neonatal early-onset sepsis (EOS). We present a case of neonatal EOS attributed

Neonatal early-onset sepsis caused by Streptococcus Gallolyticus subsp. Pasteurianus with severe pulmonary hypertension and leukemoid reaction: a case report Read More »

Neonatal pulmonary hypertension in the NICU: a 10-year single-center experience

Oguzhan Ay, Sezgin Gunes, Erkan Erfidan, Ayse SimsekIzmir Democracy University and Buca Seyfi Demirsoy Teaching and Research Hospital. Izmir City Hospital. Istanbul Aydin University and VM Medical Park Florya Hospital Istanbul. Turkey BioMedical Central PediatricsBMC Pediatr 2025; 25: DOI: 10.1186/s12887-025-05928-7 AbstractBackround Neonatal pulmonary hypertension (PHT) is a significant cause of morbidity and mortality in newborns. Early

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Clinical Profile and Morbidity Patterns in Neonates Born Through Meconium-Stained Amniotic Fluid Based on a Prospective Observational Study From a Rural Tertiary Care Center in India

Gaurav Dutta, Suresh Kumar Yadav, Ekansh Rathoria, Rohitash Lahari, Akash Srivastava, Richa RathoriaHind Institute of Medical Sciences.India CureusCureus 2025; 17: DOI: 10.7759/cureus.90332 AbstractBackground: Meconium observed in the amniotic fluid during delivery may warrant clinical monitoring due to potential neonatal complications. This study aimed to assess the incidence, risk factors, and outcomes associated with meconium aspiration syndrome

Clinical Profile and Morbidity Patterns in Neonates Born Through Meconium-Stained Amniotic Fluid Based on a Prospective Observational Study From a Rural Tertiary Care Center in India Read More »

Trends, Burden, and Inequality in Neonatal Pulmonary Arterial Hypertension: Global Estimates From 1990 to 2021

Xinbao Wang, Zhe Tang, Ziwei WangBeijing Friendship Hospital and Capital Medical University.China Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.71277 AbstractBackground: Pulmonary arterial hypertension (PAH) is a rare but life-threatening disorder in neonates, characterized by increased pulmonary vascular resistance and right heart failure. Despite advances in neonatal intensive care, the global burden of neonatal PAH remains poorly defined,

Trends, Burden, and Inequality in Neonatal Pulmonary Arterial Hypertension: Global Estimates From 1990 to 2021 Read More »

Nebulized nitroglycerin as an adjuvant drug in management of persistent pulmonary hypertension of newborns: a randomized controlled trial

Marwa Mohammed Farag, Hesham Abd El‑Rahim Ghazal, Aly Mohamed Abdel‑Mohsen, Moataz Ahmed RezkAlexandria University Hospital, Alexandria. Egypt European Journal of PediatricsEur J Pediatr 2025; 184: DOI: 10.1007/s00431-025-06381-5 AbstractThe objective was to evaluate the effect of nebulized nitroglycerin (NNG) in neonates with persistent pulmonary hypertension (PPHN). The study focused on assessing changes in echocardiographic and clinical parameters

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Risk Factors and Predictors of Mechanical Ventilation in Neonates With Meconium Aspiration Syndrome: A Retrospective Study at King Salman Armed Forces Hospital, Tabuk, Saudi Arabia

Abdulaziz A. Bedaiwi, Muhanned Amawi, Wegdan MawlanaKing Salman Armed Forces Hospital.Saudi Arabia CureusCureus 2025; 17: DOI: 10.7759/cureus.88486 AbstractBackground: Meconium aspiration syndrome (MAS) is a critical neonatal condition predominantly associated with term and post-term pregnancies, characterized by the aspiration of meconium-stained amniotic fluid (MSAF) leading to severe respiratory distress. Despite advances in obstetric and neonatal care, MAS

Risk Factors and Predictors of Mechanical Ventilation in Neonates With Meconium Aspiration Syndrome: A Retrospective Study at King Salman Armed Forces Hospital, Tabuk, Saudi Arabia Read More »

Persistent Pulmonary Hypertension Among Infants Undergoing Therapeutic Hypothermia for Hypoxic Ischemic Encephalopathy: A Systematic Review and Meta-Analysis

Rashida Javed, Tim J. Van Hasselt, Narasimha Rao, Harsha GowdaNorthampton General Hospital. University of Leicester. Madinat Zayed Hospital. University Hospitals Birmingham.United Kingdom and United Arab Emiretes Therapeutic Hypothermia and Temperature ManagementTher Hypothermia Temp Manag 2025; DOI: 10.1177/21537658251370950 AbstractTo perform a systematic review and meta-analysis to examine the association between persistent pulmonary hypertension (PPHN) and receipt of

Persistent Pulmonary Hypertension Among Infants Undergoing Therapeutic Hypothermia for Hypoxic Ischemic Encephalopathy: A Systematic Review and Meta-Analysis Read More »

Clinical Characteristics and Outcomes for Neonates with Respiratory Failure Referred for Extracorporeal Membrane Oxygenator (ECMO) Support

Pooja Musuku, Keith Meyer, Felipe E. Pedroso, Fuad Alkhoury, Balagangadhar R. TotapallyNicklaus Children’s Hospital. Herbert Wertheim College of Medicine and Florida International University.United States ChildrenChildren 2025; 12: DOI: 10.3390/children12070925 AbstractObjective: The aim of this study was to describe the presenting characteristics and outcomes of neonates with respiratory failure referred for extracorporeal membrane oxygenation (ECMO) support, compare

Clinical Characteristics and Outcomes for Neonates with Respiratory Failure Referred for Extracorporeal Membrane Oxygenator (ECMO) Support Read More »

Giant Omphalocele: Systematic Review of Pulmonary Complications and Implications for Neonatal Care

Joana Peixoto, Joana Neto, Susana Pissarra, Inês Azevedo, Henrique Soares, Gustavo RochaUniversidade do Porto. Centro Hospitalar Universitário de São João. Portugal European Journal of Pediatric SurgeryEur J Pediatr Surg 2025; DOI: 10.1055/a-2649-0781 AbstractThe primary objectives were to know the prevalences of pulmonary hypoplasia (PH), persistent pulmonary hypertension of the newborn (PPHN), and mortality in newborn infants

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