Class 1. Persistent Pulmonary Hypertension of the Newborn

Cardiology Overview of Pulmonary Hypertension Management in the Neonatal Intensive Care Unit

Rebecca J. Kameny, Rachel K. HopperStanford University.United States Clinics in PerinatologyClin Perinatol 2025; 52: 633-653DOI: 10.1016/j.clp.2025.08.002 AbstractPulmonary hypertension (PH) in the neonatal intensive care unit represents a complex and diverse spectrum of conditions, from transient persistent pulmonary hypertension of the newborn to chronic PH associated with bronchopulmonary dysplasia, congenital heart disease, and other conditions, and can

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Persistent Pulmonary Hypertension of the Newborn: A Pragmatic Review of Pathophysiology, Diagnosis, and Advances in Management

Karolina Chojnacka, Yogen Singh, Sheen Gahlaut, Witold Blaz, Agata Jerzak, Tomasz SzczapaPoznan University of Medical Sciences. University of California and UC Davis Children’s Hospital. Oxford University. Saint Jadwiga the Queen Clinical Provincial Hospital and University of Rzeszow.Poland, United States and United Kingdom BiomedicinesBiomedicines 2025; 13: DOI: 10.3390/biomedicines13102332 AbstractPersistent pulmonary hypertension of the newborn (PPHN) results from

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Abnormal Fetal/Neonatal Lung Development Manifested as Some Functional Heart Abnormalities During the Third Trimester of Fetal Life

Julia Murlewska, Oskar Sylwestrzak, Maciej Słodki, Iwona Strzelecka, Łukasz Sokołowski, Monika Wójtowicz-Marzec, Iwona Maroszynska, Ewa Cichos, Hanna Romanowicz, Anita J. Moon-Grady, Maria Respondek-LiberskaPolish Mother’s Memorial Hospital Research Institute. Mazovian Academy in Plock. Medical University of Lodz. Medical University of Lublin. Benioff Children’s Hospital and University of California, San Francisco.Poland and United States BiomedicinesBiomedicines 2025; 13:

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Two case reports of idiopathic prenatal closure of the ductus arteriosus complicated at birth by severe pulmonary hypertension successfully treated without intubation

Leonce Mwizerwa, Raphael Joye, Vladimir L. Cousin, Iliona Malaspinas, Maya Bouhabib, Hugues Lucron, Maurice Beghetti, Julie WackerGeneva University Hospitals and University of Geneva. AP-HP Paris-Saclay University and Bicêtre Hospital.Switzerland and France Translational PediatricsTrans Pediatr 2025; 14: 2374-2380DOI: 10.21037/tp-2025-264 AbstractBackground: Prenatal closure of the ductus arteriosus (DA) is an uncommon but potentially severe condition that can result in

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Outcomes in early term neonates requiring extracorporeal membrane oxygenation

Sourabh Verma, Bryn H. S. Seltzer, Jason C. Fisher, Erin CicaleseHassenfeld Children’s Hospital at New York University Langone.United States Journal of Perinatal MedicineJ Perinat Med 2025; DOI: 10.1515/jpm-2025-0235 AbstractObjectives: To evaluate ECMO-related morbidity and mortality between Early-term (ET) and Full-term (FT) infants.Methods: We performed a retrospective review of 3,831 neonatal ECMO runs for meconium aspiration syndrome (MAS) and/or

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Mobile ECMO for inter-hospital transport of pediatric patients: experience from 22 cases

Yufan Yang, Xiangni Wang, Xiulan Lu, Xinping Zhang, Jiaotian Huang, Zhenghui XiaoUniversity of South China and Hunan Children’s Hospital. Affiliated Children’s Hospital of Xiangya School of Medicine and Central South University. Hunan Traditional Chinese Medical College. Frontiers in PediatricsFront Pediatr 2025; 13: DOI: 10.3389/fped.2025.1664454 AbstractObjective: To summarize the management experience of inter-hospital transport of critically ill children

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Vardenafil vs. Sildenafil for the Treatment of Persistent Pulmonary Hypertension in Newborns

Sania El-HindiChildren’s Hospital.Syria Indian Journal of PediatricsIndian L Pediatr 2025; DOI: 10.1007/s12098-025-05787-1 AbstractAbstract Not Available CategoryClass I. Persistent Pulmonary Hypertension of the NewbornMedical Therapy. Efficacy or Lack of Efficacy Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication Article Access Free PDF File or Full Text Article

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Neonatal early-onset sepsis caused by Streptococcus Gallolyticus subsp. Pasteurianus with severe pulmonary hypertension and leukemoid reaction: a case report

Xuelian Wang, Ling Wang, Yuan Yuan, Xiaopeng Zhao, Huayan ZhangGuangzhou Women and Children’s Medical Center and Guangzhou Medical University. Children’s Hospital of Philadelphia.China and United States BioMedical Central PediatricsBMC Pediatr 2025; 25: DOI: 10.1186/s12887-025-06026-4 AbstractBackground: Streptococcus gallolyticus subsp. pasteurianus (SGSP) is an uncommon cause of neonatal early-onset sepsis (EOS). We present a case of neonatal EOS attributed

Neonatal early-onset sepsis caused by Streptococcus Gallolyticus subsp. Pasteurianus with severe pulmonary hypertension and leukemoid reaction: a case report Read More »

Neonatal pulmonary hypertension in the NICU: a 10-year single-center experience

Oguzhan Ay, Sezgin Gunes, Erkan Erfidan, Ayse SimsekIzmir Democracy University and Buca Seyfi Demirsoy Teaching and Research Hospital. Izmir City Hospital. Istanbul Aydin University and VM Medical Park Florya Hospital Istanbul. Turkey BioMedical Central PediatricsBMC Pediatr 2025; 25: DOI: 10.1186/s12887-025-05928-7 AbstractBackround Neonatal pulmonary hypertension (PHT) is a significant cause of morbidity and mortality in newborns. Early

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Clinical Profile and Morbidity Patterns in Neonates Born Through Meconium-Stained Amniotic Fluid Based on a Prospective Observational Study From a Rural Tertiary Care Center in India

Gaurav Dutta, Suresh Kumar Yadav, Ekansh Rathoria, Rohitash Lahari, Akash Srivastava, Richa RathoriaHind Institute of Medical Sciences.India CureusCureus 2025; 17: DOI: 10.7759/cureus.90332 AbstractBackground: Meconium observed in the amniotic fluid during delivery may warrant clinical monitoring due to potential neonatal complications. This study aimed to assess the incidence, risk factors, and outcomes associated with meconium aspiration syndrome

Clinical Profile and Morbidity Patterns in Neonates Born Through Meconium-Stained Amniotic Fluid Based on a Prospective Observational Study From a Rural Tertiary Care Center in India Read More »

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