Animal Models of Pulmonary Vascular Disease and Therapy Archives - Page 23 of 27

The adult heart requires baseline expression of the transcription factor Hand2 to withstand right ventricular pressure overload

Raquel F. Videira, Anne-Marie C. Koop, Lara Ottaviani, Ella M. Poels, Jordy M. M. Kocken, Cristobal Dos Remedios, Pedro Mendes-Ferreira, Kees W. Van De Kolk, Gideon J. Du Marchie Sarvaas, Andre´ Lourenc, Aida Llucia`-Valldeperas, Diana S. Nascimento, Leon J. De Windt, Frances S. DeMan, Ineˆs Falc~ao-Pires, Rolf M. F. Berger, Paula A. da Costa MartinsMaastricht […]

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Hypoxic preconditioning improves the survival and pro-angiogenic capacity of transplanted human umbilical cord mesenchymal stem cells via HIF-1α signaling in a rat model of bronchopulmonary dysplasia

Chang Hao, Jingyi You, Huijun Qiu, Ou Zhou, Jiang Liu, Wenjing Zou, Ke Yeng, Zhou Fu, Lin ZouChildren’s Hospital of Chongqing Medical University. China Biochemical and Biophysical Research CommunicationsBiochem Biophys Res Commun 2022; 605: 111-118DOI: 10.1016/j.bbrc.2022.03.044 AbstractBronchopulmonary dysplasia (BPD) is a serious chronic respiratory disease that predominates in the neonatal period. Currently, efficacious and effective specific

Hypoxic preconditioning improves the survival and pro-angiogenic capacity of transplanted human umbilical cord mesenchymal stem cells via HIF-1α signaling in a rat model of bronchopulmonary dysplasia Read More »

Type 2 immune polarization is associated with cardiopulmonary disease in preterm infants

Jason C. Lao, Christine B. Bui, Merrin A. Pang, Steven X. Cho, Ina Rudloff, Kirstin Elgass, Jan Schroder, Anton Maksimenko, Niamh E. Mangan, Malcolm R. Starkey, Elisabeth M. Skuza, Yu B. Y. Sun, Friederike Beker, Clare L. Collins, Omar F. Kamlin, Kai Konig, Atul Malhotra, Kenneth Tan, Chritiane Theda, Morag J. Young, Catriona A. McLean,

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Thrombospondin-1 Plays a Major Pathogenic Role in Experimental and Human Bronchopulmonary Dysplasia

Brittany Ann Ruschkowski, Yousef Esmaeil, Kate Daniel, Chantel Gaudet, Behzad Yeganeh, David Grynspan, Robert P. JankovChildren’s Hospital of Eastern Ontario Research Institute. University of Ottawa.Canada American Journal of Respiratory and Critical Care MedicineAm J Respir Crit Care Med 2022; 205: 685-699DOI: 10.1164/rccm.202104-1021OC AbstractRationale: Extremely preterm infants develop bronchopulmonary dysplasia (BPD), a chronic lung injury that lacks effective

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Assessing the impact of gestational age of donors on the efficacy of amniotic epithelial cell-derived extracellular vesicles in experimental bronchopulmonary dysplasia

Dandan Zhu, Mirja Krause, Tamara Yawno, Gina D. Kusuma, Renate Schwab, Mehri Barabadi, Amina S. Maleken, Siow T. Chan, Rod Hunt, David Greening, Euan M. Wallace, Rebecca LimHudson Institute of Medical Research. Monash University. La Trobe Institute for Molecular Science and La Trobe University. University of Melbourne.Australia Stem Cell Research and TherapyStem Cell Res Ther

Assessing the impact of gestational age of donors on the efficacy of amniotic epithelial cell-derived extracellular vesicles in experimental bronchopulmonary dysplasia Read More »

Metabolic Reprogramming of the Right Ventricle and Pulmonary Arteries in a Flow-Associated Pulmonary Arterial Hypertension Rat Model

Dongli Liu, Suyuan Qin, Danyan Su, Kai Wang, Yanyun Huang, Yuqin Huang, Yusheng PangThe First Affiliated Hospital of Guangxi Medical University. The First Affiliated Hospital of Wenzhou Medical University.China American Chemical Society OmegaACS Omega 2021; 7: 1273-1287DOI: 10.1021/acsomega.1c05895 AbstractPulmonary arterial hypertension (PAH) is a complex devastating disease relevant to remarkable metabolic dysregulation. Although various research studies

Metabolic Reprogramming of the Right Ventricle and Pulmonary Arteries in a Flow-Associated Pulmonary Arterial Hypertension Rat Model Read More »

Identification of the Key Pathways and Genes in Hypoxia Pulmonary Arterial Hypertension Following Intrauterine Growth Retardation

Weifen Zhu, Ziming Zhang, Weiwei Gui, Zheng Shen, Yixin Chen, Xueyao Yin, Li Liang, Lin LiThe Affiliated Sir Run Run Shaw Hospital, Children’s Hospital and The First Affiliated Hospital of Zhejiang University.China Frontiers in Molecular BiosciencesFront Mol Biosci 2022; DOI: 10.3389/fmolb.2022.789736 AbstractHigh-throughput sequencing and weighted gene co-expression network analysis (WGCNA) were used to identify susceptibility modules

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Identification of SOX2 Interacting Proteins in the Developing Mouse Lung With Potential Implications for Congenital Diaphragmatic Hernia

Kim A. A. Schilders, Gabriëla G. Edel, Evelien Eenjes, Bianca Oresta, Judith Birkhoff, Anne Boerema-de Munck, Marjon Buscop-van Kempen, Panagiotis Liakopoulos, Petros Kolovos, Jeroen A. A. Demmers, Raymond Poot, Rene M. H. Wijnen, Dick Tibboel and Robbert J. RottierErasmus Medical Center and Sophia Children’s Hospital. Democritus University of Thrace. Netherlands and Greece Frontiers in PediatricsFront

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