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A Novel Heterozygous STING1 Point Mutation Causes Pulmonary Arterial Hypertension in Children: A Case Report

Lianmei Chen, Chang Peng, Li Wang, Shuqi Wu, Ting TangGuizhou Children’s Hospital and Affiliated Hospital of Zunyi Medical University.China Pediatric PulmonologyPediatr Pulmonol 2026; 61:DOI: 10.1002/ppul.71474 AbstractAbstract Not Available CategoryGenetic Factors Associated with Pulmonary Vascular Disease Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication Article Access Free […]

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Outcome in patients with secundum type atrial septal defect – a single centre experience

Johanna Gorenflo, Victoria Ziesenitz, Mina Farag, Tsvetomir Loukanov, Matthias GorenfloUniversity Medical Centre Mannheim. Heidelberg University. Germany The Thoracic and Cardiovascular SurgeonThorac Cardiovasc Surg 2026; DOI: 10.1055/a-2786-1128 AbstractThis single centre retrospective analysis presents data from 611 patients with ASD closure. Included were patients > 2 years of age. Patients presented at a median [range] age of 6,95

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Navigating the Unique Challenge of Pulmonary Hypertension From Left-to-Right PDA Shunts in Two Cases of Congenital Diaphragmatic Hernia

John T. Wren, Jr., Rhucha Joshi, Patrick J. McNamaraUniversity of Iowa Healthcare. Children’s Hospital of Orange County. United States EchocardiographyEchocardiography 2026; 43: DOI: 10.1111/echo.70396 AbstractPulmonary hypertension (PH) in congenital diaphragmatic hernia (CDH) is nearly universal yet incredibly complex. A patent ductus arteriosus (PDA) is increasingly utilized to both monitor echocardiographically and manage CDH-PH. However, as pulmonary

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Multidisciplinary care of pediatric obesity and its impact on sleep: a review

Ravali Inja, Christopher CieloChildren’s Hospital of Philadelphia.United States Frontiers in SleepFront Sleep 2026; 4: DOI: 10.3389/frsle.2025.1634185 AbstractPediatric obesity has emerged as a significant global health issue with multifaceted consequences, including its impact on sleep health. Obstructive sleep apnea (OSA) and obesity hypoventilation syndrome (OHS) are among the serious sleep-related comorbidities in obese children, contributing to impaired

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Stratified Comparison of Risk Factors for Mild Versus Moderate-to-Severe Bronchopulmonary Dysplasia in Very Preterm Infants (< 32 Weeks Gestational Age)

Jingwen Zhu, Ming Guo, Xiyu He, Yurui Liifth Medical Center of PLA General Hospital. China Lung Lung 2026; 204: DOI: 10.1007/s00408-025-00865-9 AbstractBackground: Bronchopulmonary dysplasia (BPD) remains a significant complication in very preterm infants (< 32 weeks gestational age). Risk factors may differ between mild and moderate-to-severe BPD, but stratified analyses are limited.Objective: To compare risk factors for mild

Stratified Comparison of Risk Factors for Mild Versus Moderate-to-Severe Bronchopulmonary Dysplasia in Very Preterm Infants (< 32 Weeks Gestational Age) Read More »

High altitude pulmonary oedema in the Himalayas: a preventable condition

Tsering Norboo, Keith BallSonam Norboo Memorial Hospital.India PractitionerPractitioner 1988; 232: 557-560DOI: Not Available AbstractHigh altitude pulmonary oedema (HAPO) is an important cause of disability in those visiting the Himalayas. Many visitors and their doctors are apparently unaware of this serious and potentially lethal condition, though it can readily be prevented by ascending slowly and using

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Accentuated hypoxemia at high altitude in subjects susceptible to high-altitude pulmonary edema

Thomas M. Hyers, Charles H. Scoggin, D. H. Will, Robert F. Grover, John T. ReevesDenver Veterans Administration Hospital and University of Colorado Medical Center.United States Journal of Applied Physiology Respiratory Environmental and Exercise PhysiologyJ Appl Physiol Respir Environ Exerc Physiol 1979; 46: 41-46DOI: 10.1152/jappl.1979.46.1.41 AbstractTo investigate the hypotheses that activated coagulation, catecholamine release, or arginine vasopressin

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Histone deacetylase 3 promotes hypoxia-induced human pulmonary arterial smooth muscle cell proliferation by modulating the CSF2-JAK2-STAT5 signaling pathway

Jie Zhang, Youfei Fan, Yanting Gao, Youpeng JinShandong Provincial Hospital and Second Affiliated Hospital Affiliated to Shandong First Medical University. China Human CellHum Cell 2026; 39: DOI: 10.1007/s13577-026-01348-6 AbstractThe growth of human pulmonary arterial smooth muscle cells (hPASMCs) is one of the key contributors to vascular remodeling in pulmonary arterial hypertension (PAH). Although histone deacetylase 3

Histone deacetylase 3 promotes hypoxia-induced human pulmonary arterial smooth muscle cell proliferation by modulating the CSF2-JAK2-STAT5 signaling pathway Read More »

Pulmonary arterial hypertension after congenital heart defect correction: a call for timely diagnosis and careful risk stratification to improve outcomes

Qiangqiang Li, Yuan He, Andrew Constantine, Konstantinos Dimopoulos, Chen Zhang, Qiang Wang, Hong GuBeijing Anzhen Hospital and Capital Medical University. Queen Elizabeth Hospital Birmingham and University Hospitals Birmingham NHS Foundation Trust. Royal Brompton Hospital and Royal Brompton and Harefield NHS Foundation Trust. Imperial College London.China and United Kingdom European Heart Journal OpenEur Heart J Open

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Evaluation of therapeutic methods in high altitude pulmonary edema

Emilio Marticorena, Herbert N. HultgrenSan Marcos University and Chulec General Hospital. Palo Alto Veterans Administration Hospital and Stanford University School of Medicine. Peru and United States American Journal of CardiologyAm J Cardiol 1979; 43: 307-312DOI: 10.1016/s0002-9149(79)80020-x AbstractThe effect of treatment with bed rest alone was evaluated in 16 patients with high altitude pulmonary edema of mild

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