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Frataxin deficiency disrupts mitochondrial respiration and pulmonary endothelial cell function

Miranda K. Culley, Rashmi J. Rao, Monica Mehta, Jingsi Zhao, Wadih El Khoury, Lloyd D. Harvey, Dror Perk, Yi Yin Tai, Ying Tang, Sruti Shiva, Marlene Rabinovitch, Mingxia Gu, Thomas Bertero, Stephen Y. ChanUniversity of Pittsburgh School of Medicine and University of Pittsburgh Medical Center. Albert Einstein College of Medicine. Stanford Children’s Health and Stanford

Frataxin deficiency disrupts mitochondrial respiration and pulmonary endothelial cell function Read More »

Insulin-like growth factor binding Protein-4: A novel indicator of pulmonary arterial hypertension severity and survival

Guillermo Torres, Jun Yang, Megan Griffiths, Stephanie Brandal, Rachel Damico, Dhananjay Vaidya, Catherine E. Simpson, Michael W. Pauciulo, William C. Nichols, David D. Ivy, Eric D. Austin, Paul M. Hassoun, Allen D. EverettJohns Hopkins University. University of Texas Southwestern Medical Center. Cincinnati Children’s Hospital Medical Center. Children’s Hospital Colorado. Vanderbilt University Medical Center.United States Pulmonary

Insulin-like growth factor binding Protein-4: A novel indicator of pulmonary arterial hypertension severity and survival Read More »

Role of microRNAs in Congenital Diaphragmatic Hernia-Associated Pulmonary Hypertension

Flaminia Pugnaloni, Irma Capolupo, Neil Patel, Paola Giliberti, Andrea Dotta, Pietro Bagolan, Florian KipfmuellerBambino Gesù Children Hospital. The Royal Hospital for Children. University of Rome “Tor Vergata”. Children’s Hospital, University of Bonn.Italy, United Kingdom and Germany International Journal of Molecular SciencesInt J Mol Sci 2023; 24: DOI: 10.3390/ijms24076656 AbstractEpigenetic regulators such as microRNAs (miRNAs) have a

Role of microRNAs in Congenital Diaphragmatic Hernia-Associated Pulmonary Hypertension Read More »

Correlation of ABO blood groups with treatment response and efficacy in infants with persistent pulmonary hypertension of the newborn treated with inhaled nitric oxide

Yi Guan, Ya Jin, Yongxue Lu, Dang Ao, Pingjiao Gu, Jiyan Yang, Guosheng Liu, Shasha HanThe First Affiliated Hospital of Jinan University. The First People’s Hospital of Foshan. The Affiliated Hospital of Guangdong Medical University. Foshan Women and Children Hospital. Guangdong Women and Children Hospital. China BioMed Central Pregnancy and ChildbirthBMC Pregnancy Childbirth 2023; 23:

Correlation of ABO blood groups with treatment response and efficacy in infants with persistent pulmonary hypertension of the newborn treated with inhaled nitric oxide Read More »

Molecular Function and Contribution of TBX4 in Development and Disease

Justyna A. Karolak, Carrie L. Welch, Christian Mosimann, Katarzyna Bzdega, James D. West, David Montani, Melanie Eyries, Mary P. Mullen, Steven H. Abman, Matina Prapa, Stefan Graf, Nicholas W. Morrell, Anna R. Hemnes, Frederic Perros, Rizwan Hamid, Malcolm P. O. Logan, Jeffrey Whitsett, Csaba Galambos, Pawel Stankiewicz, Wendy K. Chung, Eric D. AustinMultiple InstitutionsPoland, France,

Molecular Function and Contribution of TBX4 in Development and Disease Read More »

Repetitive schistosoma exposure causes perivascular lung fibrosis and persistent pulmonary hypertension

Rahul Kumar, Michael H. Lee, Biruk Kassa, Dara C. Fonseca Balladares, Claudia Mickael, Linda Sanders, Adam Andruska, Maya Kumar, Edda Spiekerkoetter, Angela Bandeira, Kurt R. Stenmark, Rubin M. Tuder, Brian B. GrahamUniversity of California San Francisco. Zuckerberg San Francisco General Hospital. University of Colorado Anschutz Medical Campus. Stanford University. Universidade de Pernambuco.United States and Brazil

Repetitive schistosoma exposure causes perivascular lung fibrosis and persistent pulmonary hypertension Read More »

Egln1Tie2Cre Mice Exhibit Similar Therapeutic Responses to Sildenafil, Ambrisentan, and Treprostinil as Pulmonary Arterial Hypertension (PAH) Patients, Supporting Egln1Tie2Cre Mice as a Useful PAH Model

Yi Peng, Jingbo Dai, You-Yang ZhaoAnn and Robert H. Lurie Children’s Hospital of Chicago. Northwestern University Feinberg School of Medicine. United States International Journal of Molecular SciencesInt J Mol Sci 2023; 24: DOI: 10.3390/ijms24032391 AbstractPulmonary arterial hypertension (PAH) is a progressive and inevitably fatal disease characterized by the progressive increase of pulmonary vascular resistance and obliterative

Egln1Tie2Cre Mice Exhibit Similar Therapeutic Responses to Sildenafil, Ambrisentan, and Treprostinil as Pulmonary Arterial Hypertension (PAH) Patients, Supporting Egln1Tie2Cre Mice as a Useful PAH Model Read More »

The Role of the Interleukin-1 Family in Complications of Prematurity

Elys A. Green, Steven P. Garrick, Briana Peterson, Philip J. Berger, Robert Galinsky, Rod W. Hunt, Steven X. Cho, Jane E. Bourke, Marcel F. Nold, Claudia A. Nold-PetryHudson Institute of Medical Research. Monash University. Monash Children’s Hospital. Australia International Journal of Molecular SciencesInt J Mol Sci 2023; 24: DOI: 10.3390/ijms24032795 AbstractPreterm birth is a major contributor

The Role of the Interleukin-1 Family in Complications of Prematurity Read More »

Evaluation of levosimendan as treatment option in a large case-series of preterm infants with cardiac dysfunction and pulmonary hypertension

Lukas Schroeder, Stanley Holcher, Judith Leyens, Annegret Geipel, Brigitte Strizek, Till Dresbach, Andreas Mueller, Florian KipfmuellerUniversity Children’s Hospital Bonn. University Hospital Bonn.Germany European Journal of PediatricsEur J Pediatr 2023; DOI: 10.1007/s00431-023-04971-9 AbstractLevosimendan as a calcium-sensitizer is a promising innovative therapeutical option for the treatment of severe cardiac dysfunction (CD) and pulmonary hypertension (PH) in preterm infants,

Evaluation of levosimendan as treatment option in a large case-series of preterm infants with cardiac dysfunction and pulmonary hypertension Read More »

Targeted neonatal echocardiography and lung ultrasound in preterm infants with chronic lung disease with and without pulmonary hypertension, screened using a standardized algorithm

Janneth Cristina Sánchez-Becerra, Rogelio Guillén-Torres, Rosario Becerra-Becerra, Horacio Márquez-González, Daniel Ibarra-RíosNational Institute of Health and Hospital Infantil de México Federico Gómez.Mexico Frontiers in PediatricsFront Pediatr 2023; 11: DOI: 10.3389/fped.2023.1104940 AbstractIntroduction: Increased recognition of the development of chronic pulmonary hypertension (cPH) in preterm infants with chronic lung disease (CLD) has prompted enhanced monitoring for the identification of different

Targeted neonatal echocardiography and lung ultrasound in preterm infants with chronic lung disease with and without pulmonary hypertension, screened using a standardized algorithm Read More »

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