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Understanding how methyltransferase-like 3 functions in lung diseases: From pathogenesis to clinical application

Deshuang Zhang, Zhixian Gou, Yi Qu, Xiaojuan SuWest China Second University Hospital and Sichuan University. School of Clinical Medicine and First Affiliated Hospital of Chengdu Medical College. China Biomedicine and PharmacotherapyBiomed Pharmacother 2024; DOI: 10.1016/j.biopha.2024.117421 AbstractLung diseases have complex pathogenesis and treatment challenges, showing an obvious increase in the rate of diagnosis and death every year. […]

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Patterns and Outcomes of Epoprostenol Use in Infants with Congenital Diaphragmatic Hernia Requiring Extracorporeal Life Support

Nikhil R. Shah, Keerthi Burgi, Dimitra M. Lotakis, Mary K. Olive, Amanda D. McCormick, Erin E. Perrone, Joseph T. Church, George B. MychaliskaC.S. Mott Children’s Hospital, Michigan Medicine and University of Michigan Medical School. United States Journal of PediatricsJ Pediatr 2024; DOI: 10.1016/j.jpeds.2024.114286 AbstractObjective: To describe our experience utilizing epoprostenol for pulmonary hypertension (PH) in infants with

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Congenital cytomegalovirus and pulmonary hypertension

Layah Alkoby-Meshulam, Jacob Amir, Daniel Lubin, Gil Klinger, Giora Guttesman, Samuel Zangen, Efraim BilavskySchneider Children’s Medical Center. Tel Aviv University. Mayanei Hayeshua Medical Center. Meir Medical Center. Barzilai Medical Center.Israel Congenital AnomaliesCongenit Anom 2024;DOI: 10.1111/cga.12580 AbstractLung involvement in children with congenital cytomegalovirus infection has been scarcely described. We describe three new cases of persistent pulmonary hypertension

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Covid-19-induced pulmonary hypertension in children, and the use of phosphodiesterase-5 inhibitors

Herlina Dimiati Dimas Arya Umara, Iflan NaufalUniversitas Syiah Kuala,Indonesia F1000 ResearchF1000Res 2022; DOI: 10.12688/f1000research.53966.2 AbstractRespiratory tract infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) first occurred in Wuhan, China, in December 2019 and was declared as a pandemic by WHO. The interaction between the 2019 coronavirus disease (COVID-19) and pulmonary hypertension (PH) in children

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Swyer-James-MacLeod Syndrome in a Patient with Eisenmenger Syndrome

Dolunay Gürses, Merve Oğuz, Doğangün Yüksel, Furkan Ufuk, Münevver YılmazPamukkale University Medical School. Turkey Archives of the Turkish Society of CardiologyTurk Kardiyol Dern Ars 2024; 52: 460-463DOI: 10.5543/tkda.2023.59829 AbstractSwyer-James-MacLeod syndrome is characterized radiologically by hyperlucency in a single lung lobe, accompanied by reduced vascularity, alveolar hyperdistention, and air trapping, without bronchial airway obstruction. The most common

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Unraveling the Mfn2-Warburg effect nexus: a therapeutic strategy to combat pulmonary arterial hypertension arising from catch-up growth after IUGR

Lingling Yan, Xiaofei Luo, Chengcheng Hang, YuWang, Ziming Zhang, Shanshan Xu, Lizhong DuChildren’s Hospital and First Affiliated Hospital of Zhejiang University School of Medicine. China Respiratory ResearchRespir Res 2024; 25: DOI: 10.1186/s12931-024-02957-1 AbstractBackground: The interplay between intrauterine and early postnatal environments has been associated with an increased risk of cardiovascular diseases in adulthood, including pulmonary arterial hypertension

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Impact of Age and of the Patent Ductus Arteriosus on Pulmonary Hemodynamics in Children with Complete Atrioventricular Septal Defect

Lucas Oliveira Rocha, Nelson Itiro Miyague, Leo Agostinho Solarewicz, Miguel Morita Fernandez-SilvaHospital Infantil Pequeno Príncipe. Universidade Federal do Paraná.Brazil Pediatric CardiologyPediatr Cardiol 2024; DOI: 10.1007/s00246-024-03636-0 AbstractComplete atrioventricular septal defect (CAVSD) can lead to the development of pulmonary obstructive vascular disease due to high pulmonary blood flow and pressures. This study aimed to evaluate the changes in

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Exploring Stress and Coping in Caregivers of Children with Pulmonary Vein Stenosis: A Mixed-Method Study

Mark Fuller, Jr., Christina Ireland, Rachel Zmora, Kathy JenkinsBoston Children’s Hospital and Harvard Medical School. Northwestern University Feinberg School of Medicine.United States ChildrenChildren 2024; 11: DOI: 10.3390/children11081008 AbstractBackground: This mixed-method study aims to identify and describe factors associated with acute and long-term parenting stressors and coping strategies in caregivers of children with intraluminal pulmonary vein stenosis

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Biomarker screening for pulmonary hypertension in VLBW infants at risk for bronchopulmonary dysplasia

Fernando A. Munoz, Amanda Kim, Brendan Kelly, Emma Olson Jackson, Patrick D. Evers, Daniel Morrow, Amy McCammond, Brian K. Jordan, Brian Scottoine Oregon Health & Science University. Seattle Children’s Hospital. PeaceHealth Sacred Heart Medical Center at Riverbend. University of California San Francisco.United States Pediatric ResearchPediatr Res 2024; DOI: 10.1038/s41390-024-03517-5 AbstractBackground: Very low birth weight (VLBW) infants demonstrate altered

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Persistent pulmonary hypertension and short-term neurological outcomes in infants with moderate to severe hypoxic ischemic encephalopathy

R. Ismail, Erika Vorhies, K. Mohammad, Amuchou Soraisham, J. Scott, Amelie StritzkeCumming School of Medicine. University of Calgary. Libin Cardiovascular Institute of Alberta. Canada Journal of Neonatal-Perinatal MedicineJ Neonatal Perinatal Med 2024; 17: 597-605DOI: 10.3233/NPM-230032 AbstractBackground: Our aim was to investigate the relationship between persistent pulmonary hypertension of the newborn (PPHN), short-term brain injury or death, and

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