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Cardiac performance and left ventricular dimensions in neonates with left-sided congenital diaphragmatic hernia before and after surgical repair

Mohamed Mahmoud Shalaby, Fatma Aboalsoud TahaTanta University.Egypt Journal of Cardiothoracic SurgeryJ Cardiothorac Surg 2026; DOI: 10.1186/s13019-026-04289-1 AbstractBackground: Congenital Diaphragmatic Hernia (CDH) is associated with significant cardiopulmonary morbidity. Pulmonary Hypertension (PH) and left ventricular (LV) dysfunction are major determinants of outcome. While the impact of CDH repair on pulmonary hemodynamics is recognized, comprehensive serial assessment of cardiac performance,

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Diffusion of carbon monoxide in the lungs and pulmonary artery pressures in school aged children who were born preterm

Christopher Harris, Allan Jenkinson, Sanja Zivanovic, Kuberan Pushparajah, Theodore Dassios, Steven H. Abman, Anne GreenoughKing’s College London, King’s College Hospital NHS Foundation Trust and Imperial College Healthcare NHS Trust. University of Colorado School of Medicine.united Kingdom and United States Pediatric ResearchPediatr Res 2026; DOI: 10.1038/s41390-026-05260-5 AbstractBackground: Premature birth is associated with altered pulmonary vascular development and raised

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SnRNA-seq identifies FN1-SDC4 axis triggering epicardial activation in right ventricular remodeling in pulmonary hypertension

Xiao-He Xu, Yi Shen, Min Chen, Yu-Xin Miao, Lin Cheng, Yang-Han-Yue Zhao, Yang Fang, Dai-Ji Jiang, Fang Yu, Yang-Yang He, Zhuo-Yuan Xu, Li-Jun Fu, Li-Wei Wu, Hao Zhang, Yi YanShanghai Children’s Medical Center, National Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Henan University. Second Affiliated Hospital, Yuying Children’s Hospital, Wenzhou Medical

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Cardiac Index Measured Using the Fick Principle Versus Thermodilution in Children Following Orthotopic Heart Transplantation

Elyssa Cohen, Conor O’Halloran, Nicholas Pilli, Paul TannousAnn and Robert H. Lurie Children’s Hospital of Chicago.United States Pediatric CardiologyPediatr Cardiol 2026; DOI: 10.1007/s00246-026-04302-3 AbstractCardiac index (CI) is used to assess graft function and calculate pulmonary vascular resistance (PVR) following orthotopic heart transplantation (OHT). The gold standard is thermodilution (TD), but in practice, the Fick method using

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Off-Label Sotatercept Use in Pediatric Pulmonary Arterial Hypertension: A Single-Center Retrospective Hemodynamic Study

Dhruv Rao, Shylah Haldeman, Jeanne Carroll, Rohit RaoUniversity of Arizona, Tucson. Rady Children’s Hospital-San Diego and University of California San DiegoUnited States Pediatric CardiologyPediatr Cardiol 2026; DOI: 10.1007/s00246-026-04349-2 AbstractSotatercept, a first-in-class activin signaling inhibitor, has demonstrated disease-modifying efficacy in adults with pulmonary arterial hypertension (PAH). Pediatric data remain limited to ongoing clinical trials. We conducted an

Off-Label Sotatercept Use in Pediatric Pulmonary Arterial Hypertension: A Single-Center Retrospective Hemodynamic Study Read More »

L-Citrulline: Novel Pharmacotherapy to Improve Outcomes in Infants and Children at Risk of Systemic or Pulmonary Vascular Disease

Candice D. Fike, Frederick E. Barr, Judy L. AschnerUniversity of Utah Health. Diversified Search Group. Hackensack Meridian School of Medicine.United States PharmaceuticalsPharmaceuticals 2026; 19: DOI: 10.3390/ph19060896 AbstractInfants and children suffering from a variety of heart, lung, and blood disorders are known to be at risk of developing systemic or pulmonary vascular disease. Despite progress made in

L-Citrulline: Novel Pharmacotherapy to Improve Outcomes in Infants and Children at Risk of Systemic or Pulmonary Vascular Disease Read More »

L-Citrulline in Maternal-Fetal and Neonatal Health: Metabolic Mechanisms and Emerging Therapeutic Applications

Ana Collins-Smith, Sangeeta Jain, Sunil JainUniversity of Texas Medical Branch at Galveston.United States NutrientsNutrients 2026; 18: DOI: 10.3390/nu18121923 AbstractL-citrulline is a non-protein amino acid with critical roles in perinatal and neonatal physiology through the intestinal-renal arginine-citrulline axis and nitric oxide (NO) production. During pregnancy, L-citrulline supports placental angiogenesis, vascular adaptation, and fetal growth through augmentation of

L-Citrulline in Maternal-Fetal and Neonatal Health: Metabolic Mechanisms and Emerging Therapeutic Applications Read More »

Inhaled Nitric Oxide via High-Flow Nasal Cannula in Postrepair Congenital Heart Disease Patients With Pulmonary Arterial Hypertension Following Extubation: A Cohort Study With Propensity Score Matching

Xiaofeng Wang, Qinnan Chen, Shilin Wang, Zhiyuan Zhu, Hong Gu, Xu WangNational Center for Cardiovascular Disease and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College. Beijing Anzhen Hospital and Capital Medical University.China World Journal of Pediatric and Congenital Heart SurgeryWorld J Pediatr Congenit Heart Surg 2026; DOI: 10.1177/21501351261450515 AbstractObjective: For pediatric patients with

Inhaled Nitric Oxide via High-Flow Nasal Cannula in Postrepair Congenital Heart Disease Patients With Pulmonary Arterial Hypertension Following Extubation: A Cohort Study With Propensity Score Matching Read More »

Congenital chylothorax in infants: An updated scoping review

A. Alghobaishi, S. I. Albraim, H. I. Albraim, N. S. Gubari, S. Khan, H. I. Thalib, S. AlaghaKing Fahad Armed Forces Hospital. Saudi German Hospital. MyClinic. Batterjee Medical College. Saudi Arabia African Journal of Thoracic and Critical Care MedicineAfr J Thorac Crit Care Med 2026; 32: DOI: 10.7196/AJTCCM.2025.v32i1.2701 AbstractBackground: Chylothorax is a medical condition characterised by the

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Volumetric Capnography for Assessing Pre- and Post-Operative Intrapulmonary Shunt in Congenital Pulmonary Lymphangiectasia: A Case Report

Masashi Zuiki, Norihiro Iwata, Kazunori Watanabe, Akihiro Taniguchi, Maho Inoue, Kiyokazu Kin, Sayaka Yuguchi, Eisuke Ichise, Kanae Hashiguchi, Daisuke Kinoshita, Tatsuji Hasegawa, Shigeru Ono, Tomoko Ieharayoto Prefectural University of MedicineJapan Pediatric PulmonologyPediatr Pulmonol 2026; 61: DOI: 10.1002/ppul.71699 AbstractAbstract Not Available CategoryPrimary Pulmonary Lymphatic DiseaseDiagnostic Testing for Pulmonary Vascular Disease. Non-invasive Testing Age Focus: Pediatric Pulmonary Vascular

Volumetric Capnography for Assessing Pre- and Post-Operative Intrapulmonary Shunt in Congenital Pulmonary Lymphangiectasia: A Case Report Read More »

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