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Neonatal mortality and morbidity in Down syndrome in the time of prenatal aneuploidy testing: a retrospective cohort study

Maurike Dorothea de Groot‑van der Mooren, Lukas Augustinus, Johannes Rammeloo. Roos van der Plas, Peter de Winter, Hester van Wieringen, Anne‑Marie van Wermeskerken, Michel Emile Weijerman, Anton Hubertus van KaamAmsterdam UMC Location and University of Amsterdam. Amsterdam Public Health Research Institute. Amsterdam Reproduction & Development Research Institute. St. Antonius Ziekenhuis. Flevoziekenhuis, Hospitaalweg. Spaarne Gasthuis. KU Leuven. Alrijne Hospital. Netherlands European Journal of PediatricsEur J Pediatr 2023; 182: 319-328DOI: 10.1007/s00431-022-04686-3 AbstractThe total uptake of prenatal aneuploidy screening for Down syndrome […]

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Outpatient prescription of pulmonary vasodilator therapy to preterm children with bronchopulmonary dysplasia

Ida Jeremiasen, Karin Tran-Lundmark, Mikaela Dolk, Estelle NaumburgLund University and Skåne University Hospital. Umeå University.Sweden Acta PaediatricaActa Paediatr 2023; 112: 409-416DOI: 10.1111/apa.16615 Abstract Aim: The use of pulmonary vasodilator therapy in children born preterm is largely unknown. Our aim was to map prescription patterns in children with bronchopulmonary dysplasia in Sweden.Methods: This was a descriptive national registry-based study

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Pharmacokinetics of L-Citrulline in Neonates at Risk of Developing Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension

Candice D. Fike, Charul Avachat, Angela K. Birnbaum, Judy L. Aschner, Catherine M. SherwinUniversity of Utah Health. University of Minnesota. Hackensack Meridian School of Medicine. Wright State University Boonshoft School of Medicine and Dayton Children’s Hospital.United States Paediatric DrugsPaediatr Drug 2023; 25: 87-96DOI: 10.1007/s40272-022-00542-x AbstractBackground: Options to treat pulmonary hypertension (PH) in neonates with bronchopulmonary dysplasia (BPD)

Pharmacokinetics of L-Citrulline in Neonates at Risk of Developing Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension Read More »

Efficacy of sildenafil and high-dose anakinra in an MIS-C patient with pulmonary vasculitis: A case report

Francesco La Torre, Gerolmina Calabrese, Katia Signorile, Francesca Bizzoco, Carla Mastrorilli, Antonella Strippoli, Doriana Amato, Francesco Carella, Ugo Vairo, Paola Giordano, Leonardo Milella, Fabio CardinaleGiovanni XXIII Pediatric Hospital and University of Bari. Italy Frontiers in PediatricsFront Pediatr 2023; DOI: 10.3389/fped.2022.1015617 AbstractMultisystem inflammatory syndrome in children (MIS-C) is a newly identified clinical entity still not very well

Efficacy of sildenafil and high-dose anakinra in an MIS-C patient with pulmonary vasculitis: A case report Read More »

Successful rapid staged hybrid approach for obstructed total anomalous pulmonary venous connection

Sameh M. Said, Elizabeth A. Braunlin, James Berry, Ashley Loomis, Gurumurthy, HiremathMaria Fareri Children’s Hospital and Westchester Medical Center. Masonic Children’s Hospital and University of Minnesota. United States Journal of Cardiac SurgeryJ Card Surg 2022; 37: 5501-5504DOI: 10.1111/jocs.17053 AbstractObstructed total anomalous pulmonary venous connection (TAPVC) represents a true pediatric cardiac emergency. The patient may present in

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High altitude pulmonary edema in children: A systematic review

Santiago Ucros, Camila Aparicio, Jose Castro-Rodriguez, D. Dunbar IvyUniversidad de los Andes School of Medicine. Pontificia Universidad Católica de Chile. Children’s Hospital Colorado and University of Colorado School of Medicine.Columbia, Chile and United States Pediatric PulmonologyPediatr Pulmonol 2023; 58: 1059-1067DOI: 10.1002/ppul.26294 AbstractIntroduction: High altitude pulmonary edema (HAPE) is a form of acute noncardiogenic pulmonary edema caused by

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Surgical and Cardiac Catheterization Outcomes of Scimitar Syndrome Patients: A Three Decade Single-Center Experience

Emma Seymour, George Mallory, Raysa Morales-DemoriBaylor College of Medicine and Texas Children’s Hospital.United States Pediatric CardiologyPediatr Cardiol 2023; 44: 579-586DOI: 10.1007/s00246-022-02965-2 AbstractScimitar syndrome (SS) is a rare congenital condition which includes partial anomalous pulmonary venous return (PAPVR) and a variable degree of pulmonary hypoplasia. We describe the clinical features, therapeutic approach and outcomes of patients who

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Effects of uteroplacental insufficiency on cardiac development in growth-restricted newborn rats

Hsiu-Chu Chou, Chung-Ming ChenTaipei Medical University.Taiwan Journal of the Developmental Origins of Health and DiseaseJ Dev Orig Health Dis 2023; 14: 272-278DOI: 10.1017/S2040174422000575 AbstractFetal growth restriction (FGR) is associated with reduced cardiac function in neonates. Uteroplacental insufficiency (UPI) is the most common cause of FGR. The mechanisms underlying these alterations remain unknown. We hypothesized that UPI

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High-level gonosomal mosaicism for a pathogenic non-coding CNV deletion of the lung-specific FOXF1 enhancer in an unaffected mother of an infant with ACDMPV

Esra Yıldız Bölükbaşi, Tomasz Gambin, Justyna A. Karolak, Nicholas Willard, Przemyslaw Szafranski, Steven H. Abman, Csaba Galambos, John P. Kinsella, Paweł StankiewiczBaylor College of Medicine. Poznan University of Medical Sciences. Warsaw University of Technology. University of Colorado Anschutz Medical Campus.United States and Poland Molecular Genetics and Genomic MedicineMol Genet Genomic Med 2022; 10: DOI: 10.1002/mgg3.2062 AbstractBackground: Alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV) results

High-level gonosomal mosaicism for a pathogenic non-coding CNV deletion of the lung-specific FOXF1 enhancer in an unaffected mother of an infant with ACDMPV Read More »

The biventricular contribution to chronic pulmonary hypertension of the extremely premature infant

Gabriela de Carvalho Nunes, Punnanee Wutthigate, Jessica Simoneau, Adrian Dancea, Marc Beltempo, Claudia Renaud, Gabriel AltitMcGill University Health Centre and Montreal Children’s Hospital. Siriraj Hospital and Mahidol University. Canada and Thailand Journal of PerinatologyJ Perinatol 2023; 43: 174-180DOI: 10.1038/s41372-022-01497-0 AbstractObjective: Evaluate factors associated with significant pulmonary hypertension [PH] (≥2/3 systemic) and its impact on ventricular function at

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