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G6pdN126D Variant Increases the Risk of Developing VEGFR (Vascular Endothelial Growth Factor Receptor) Blocker-Induced Pulmonary Vascular Disease

Christina Signoretti, Shun Matsumura, Samuel Fatehi, Melinee D’Silva, Rajamma Mathew, Francesca Cendali, Angelo D’Alessandro, S. M. Shafiqul Alam, Victor Garcia, Joseph M. Miano, Sachin A. GupteNew York Medical College. University of Colorado Anschutz Medical Campus. Medical College of Georgia at Augusta University. United States Journal of the American Medical AssociationJ Am Heart Assoc 2024; DOI: 10.1161/JAHA.123.035174 AbstractBackground: G6PD (glucose-6-phosphate-dehydrogenase) is a key enzyme in the glycolytic pathway and has been implicated in the pathogenesis of cancer […]

G6pdN126D Variant Increases the Risk of Developing VEGFR (Vascular Endothelial Growth Factor Receptor) Blocker-Induced Pulmonary Vascular Disease Read More »

Echocardiographic Predictors of Hospital Outcomes in Preterm Neonates with Patent Ductus Arteriosus and Clinical Suspicion of Pulmonary Hypertension

Kristen Graff, Julie R. Ross, Kristen Morella, Shahryar M. ChowdhuryMedical University of South Carolina.United States Journal of NeonatologyJ Neonatol 2023; 37: 384-389DOI: 10.1177/09732179231178127 AbstractBackground: Preterm neonates often have an echocardiogram performed in the first few days of life for suspicion of pulmonary hypertension and patent ductus arteriosus. The usefulness of this echocardiogram in predicting outcomes in this

Echocardiographic Predictors of Hospital Outcomes in Preterm Neonates with Patent Ductus Arteriosus and Clinical Suspicion of Pulmonary Hypertension Read More »

Inhibition of DLL4/Notch Signaling Pathway Promotes M2 Polarization and Cell Proliferation in Pulmonary Arterial Hypertension

Guangxing Tan, Chenxia Juan, Yan Mao, Gang Xue, Zhuyuan FangJiangsu Province Hospital of Chinese Medicine, Wuxi Hospital of Traditional Chinese Medicine and Affiliated Hospital of Nanjing University of Chinese Medicine. Yangzhou Hospital of Traditional Chinese Medicine. China American Chemical Society OmegaACS Omega 2024; 9: 37923-37933DOI: 10.1021/acsomega.4c04307 AbstractIn this study, we conducted a comprehensive analysis to identify

Inhibition of DLL4/Notch Signaling Pathway Promotes M2 Polarization and Cell Proliferation in Pulmonary Arterial Hypertension Read More »

Long-term outcomes of transcatheter atrial septal defect closure: a single-center retrospective study

Lalita Honghiranrueng, Supaporn Roymanee, Kanjarut Wongwaitaweewong, Jirayut Jarutach, Rujira BuntharikpornpunQueen Sirikit National Institute of Child Health. Prince of Songkla University.Thailand Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2024; 11: DOI: 10.3389/fcvm.2024.1448967 AbstractBackground: Transcatheter atrial septal defect (ASD) closure is the primary approach for treating ASD secundum; however, data on long-term outcomes remain limited. This study aimed to elucidate

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Bronchopulmonary dysplasia and ventilation-associated outcomes after pediatric tracheostomy

Stephen R. Chorney, Dylan R. Beams, Arushii Nadar, Folashade Afolabi, Andrew Gelfand, Rebecca Brooks, Yann-Fuu Kou, Romaine F. JohnsonUniversity of Texas Southwestern Medical Center and Children’s Health.United States Pediatric PulmonologyPediatr Pulmonol 2024; DOI: 10.1002/ppul.27247 AbstractObjectives: The objective of this study is to determine the time to ventilator liberation and decannulation after tracheostomy placement in children with bronchopulmonary

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Echocardiographic markers at diagnosis of persistent pulmonary hypertension of the newborn

Sujith S. Pereira, Xander Jacquemyn, Shelby KuttyHomerton University Hospital and Homerton Healthcare NHS Foundation Trust. Barts and the London School of Medicine. Johns Hopkins Hospital. KU Leuven.United Kingdom, United States and Belgium Journal of Perinatal MedicineJ Perinat Med 2024; DOI: 10.1515/jpm-2023-0346 AbstractObjectives: Clinical parameters along with echocardiographic markers are used to interrogate the haemodynamics in persistent pulmonary

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Circulating Endothelin 1 but Not Transforming Growth Factor-β Levels Are Reduced after Pulmonary Endarterectomy in Subjects Affected by Chronic Thromboembolic Pulmonary Hypertension: A Prospective Cohort Study

Pasquale Totaro, Claudio Tirelli, Lucia Sacchi, Annalisa De Silvestri, Mara DeAmici, Fabrizio Grosjean, Giorgia Testa, Alessia Alloni, Eraldo Kushta, Riccardo Albertini, Teresa Rampino, Andrea Maria D’ArminiFoundation I.R.C.C.S. Policlinico San Matteo. University of Milan. University of Pavia. Italy Journal of Clinical MedicineJ Clin Med 2024; DOI: 10.3390/jcm13174977 AbstractBackground and objectives: Endothelin-1 (ET-1) and transforming growth factor-β (TGF-β) play

Circulating Endothelin 1 but Not Transforming Growth Factor-β Levels Are Reduced after Pulmonary Endarterectomy in Subjects Affected by Chronic Thromboembolic Pulmonary Hypertension: A Prospective Cohort Study Read More »

Omic-signature of bronchopulmonary dysplasia associated pulmonary hypertension in <1500g-birth-weight-infants with hemodynamically significant intracardiac shunt

Lucy Emery, Alexa Hughes, Christiana Oji-Mmuo, Patricia Silveyra, Vincent P. R. Aluquin, Ann Donnelly, Roopa SiddaiahPenn State Health College of Medicine and Penn State Health Children’s Hospital. Indiana University School of Medicine. United States Pediatric ResearchPediatr Res 2024; DOI: 10.1038/s41390-024-03541-5 AbstractBackground: PDA and ASD are common intracardiac shunts noted in prematurely born infants. While there is evidence

Omic-signature of bronchopulmonary dysplasia associated pulmonary hypertension in <1500g-birth-weight-infants with hemodynamically significant intracardiac shunt Read More »

Thiamine: An indispensable regulator of paediatric neuro-cardiovascular health and diseases

Ysphaneendramallimoggala, Monalisa Biswas, Stanly Elstin Anburaj, Faiza Iqbal. Shrikiran, Varashree Bolar Suryakanth Leslie Edward S. LewisKasturba Medical College and Manipal Academy of Higher Education. India European Journal of PediatricsEur J Pediatr 2024; DOI: 10.1007/s00431-024-05756-4 AbstractThe sustainable developmental goals emphasize good health, reduction in preventable neonatal and under-five mortalities, and attaining zero hunger. However, South Asian countries

Thiamine: An indispensable regulator of paediatric neuro-cardiovascular health and diseases Read More »