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Metallomics in pulmonary arterial hypertension patients

Karim El-Kersh, C. Danielle Hopkins, Xiaoyong Wu, Shesh N. Raj, Matthew C. Cave, M. Ryan Smith, Young-Mi Go, Dean P. Jones, Lu Cai, Jiapeng HuangUniversity of Nebraska Medical Center. University of Louisville School of Medicine. University of Cincinnati.  Emory University.United States Pulmonary CirculationPulm Circ 2023; DOI: 10.1002/pul2.12202 AbstractPulmonary arterial hypertension (PAH) prevalence is increasing worldwide, and […]

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NT-proBNP and Zlog-transformed NT-proBNP values predict extubation failure in critically ill neonates with pulmonary hypertension and ventricular dysfunction

Lukas Schroeder, Manuel Kuelshammer, Ramona Dolsheid-Pommerich, Stefan Holdenrieder, Andreas Mueller, Florian KipfmuellerUniversity Children’s Hospital Bonn. University Hospital Bonn. Technical University Munich.Germany Pediatric PulmonologyPediatr Pulmonol 2023; 58: 253-261DOI: 10.1002/ppul.26193 AbstractObjectives: Critically ill neonates with a history of pulmonary hypertension (PH) or ventricular dysfunction are at risk to experience an extubation failure (EF) after liberation from mechanical ventilation (MV).

NT-proBNP and Zlog-transformed NT-proBNP values predict extubation failure in critically ill neonates with pulmonary hypertension and ventricular dysfunction Read More »

Genetic counselling and testing in pulmonary arterial hypertension: a consensus statement on behalf of the International Consortium for Genetic Studies in PAH

Christina A. Eichstaedt, Catharina Belge, Wendy K. Chung, Stefan Gräf, Ekkehard Grünig, David Montani, Rozenn Quarck, Jair A. Tenorio-Castano, Florent Soubrier, Richard C. Trembath, Nicholas W. MorrellHeidelberg University Hospital. University of Leuven. Columbia University. University of Cambridge. Université Paris-Saclay. Hôpital Marie Lannelongue. Hospital Universitario La Paz. Centro de Investigación Biomédica en Red de Enfermedades Raras.

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Comparison of living-donor lobar lung transplantation and cadaveric lung transplantation for pulmonary hypertension

Hidenao Kayawake, Satona Tanaka, Yoshito Yamada, Shiro Baba, Hideyuki Kinoshita, Kazuhiro Yamazaki, Tadashi Ikeda, Kenji Minatoya, Yojiro Yutaka, Masatsugu Hamaji, Akihiro Ohsumi, Daisuke Nakajima, Hiroshi DateKyoto University. Kobe City Medical Center General Hospital.Japan European Journal of Cardiothoracic SurgeryEur J Cardiothorac Surg 2023; DOI: 10.1093/ejcts/ezad024 AbstractObjectives: Living-donor lobar lung transplantation (LDLLT) is a life-saving procedure for critically ill

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Ambrisentan for in pediatric pulmonary arterial hypertension: a cost-utility analysis

Jefferson Antonio Buendia, Diana Guerrero Patino, Erika Fernanda LindarteUniversity of Antioquia.Columbia Pediatric PulmonologyPediatr Pulmonol 2023; DOI: 10.1002/ppul.26361 AbstractIntroduction: Despite the growing evidence of efficacy, little is known regarding the efficiency of ambrisentan to decrease cost and improve the functional classes of pediatric patients with Pulmonary arterial hypertension. This study aims to determine the cost-utility of ambrisentan regarding

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Eliminating Senescent Cells Can Promote Pulmonary Hypertension Development and Progression

Emmanuel Born, Larissa Lipskaia, Marielle Breau, Amal Houssaini, Delphine Beaulieu, Elisabeth Marcos, Remi Pierre, Marcio Do Cruzeiro, Marine Lefevre, Genevieve Derumeaux, Dmitry V. Bulavin, Marion Delcroix, Rozenn Quarck, Virinder Reen, Jesus Gil, Daviv Bernard, Jean-Michel Flaman, Serge Adnot, Shariq AbidUniversité Paris-Est Créteil. Université de Lyon. Institut Cochin. Institut Mutualiste Montsouris. nstitute for Research on Cancer

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Increased myocardial oxygen consumption rates are associated with maladaptive right ventricular remodeling and decreased event-free survival in heart failure patients

Ali Ahmadi, Jennifer M. Renaud, Steven Promislow, Ian G. Burwash, Girish Dwivedi, Ran Klein, Jason G. E. Zelt, Robert A. deKamp, Rob S. Beanlands, Lisa M. MielniczukUniversity of Ottawa.Canada Journal of Nuclear CardiologyJ Nucl Cardiol 2021; 28: 2784-2795DOI: 10.1007/s12350-020-02144-x AbstractBackground: Reduced left ventricular (LV) function is associated with increased myocardial oxygen consumption rate (MVO2) and altered sympathetic

Increased myocardial oxygen consumption rates are associated with maladaptive right ventricular remodeling and decreased event-free survival in heart failure patients Read More »

Right Ventricular Maladaptation to Pressure Overload in Fischer Rats Is Associated With Profound Deficiency in Adenylate Kinase 1 and Impaired Ventricular Energetics

Jason G. E. Zelt, Virgilio Cadete, Yupu Deng, Rafael Godoy, Alexanne Cuillerier, Katelynn Rowe, Mohammad Abdul-Ghani, Lynn Megeney, Yan Burelle, Antonio Giulivi, Alexandre F. R. Stewart, Steeve Provencher, Sandra Breuils-Bonnet, Sébastien Bonnet, Robert deKemp, Rob Beanlands, Lisa M. Mielniczuk, Duncan J. StewartUniversity of Ottawa.Canada HypertensionHypertension 2022; 79: 2774-2786DOI: 10.1161/HYPERTENSIONAHA.122.19300 AbstractBackground: We explored the mechanism of maladaptive right

Right Ventricular Maladaptation to Pressure Overload in Fischer Rats Is Associated With Profound Deficiency in Adenylate Kinase 1 and Impaired Ventricular Energetics Read More »

Patent ductus arteriosus and the risk of bronchopulmonary dysplasia-associated pulmonary hypertension

Hythem Nawaytou, Nancy K. Hills, Ronald I. ClymanUniversity of California San Francisco.United States Pediatric ResearchPediatr Res 2023; DOI: 10.1038/s41390-023-02522-4 AbstractBackground: The aim of the study was to determine whether prolonged exposure to a moderate/large patent ductus arteriosus left-to-right shunt (PDA) increases the risk of late (beyond 36 weeks) pulmonary hypertension (BPD-PH) and pulmonary vascular disease (BPD-PVD) during

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Multicenter review of a tadalafil suspension formulation for infants and children with pulmonary hypertension: A North American experience

David Edward Youssef, Stephanie S. Handler, Susan Marjorie Richards, Catherine Anne Sheppard, Jenna Smith, Kathryn Tillman, Matthew Pietrosanu, Edward Kirkpatrick, Angela Bates University of Alberta and Stollery Children’s Hospital. Medical College of Wisconsin.Canada and United States Frontiers in PediatricsFront Pediatr 2023; DOI: 10.3389/fped.2023.1055131 AbstractIntroduction: Phosphodiesterase type 5 (PDE5) inhibitors, with sildenafil the earliest among them, are widely used

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