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Postoperative Pulmonary Hemodynamics and Systemic Inflammatory Response in Pediatric Patients Undergoing Surgery for Congenital Heart Defects

Maria Francilene S. Souza, Juliano G. Penha, Nair Y. Maeda, Filomena R. B. G. Galas, Kelly C. O. Abud, Eloisa S. Carvalho, Ana Maria Thomaz, Claudia R. P. Castro, Juliana Pereira, Antonio Augusto LopesUniversity of São Paulo School of Medicine. Brazil Mediators of InflammationMediator Inflamm 2022; DOI: 10.1155/2022/3977585 AbstractThere is scarce information about the relationships between […]

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An electrochemical nitric oxide generator for in-home inhalation therapy in pulmonary artery hypertension

Yiwei Liu, Yifan Zhu, Chenyu Jiang, Zhanhao Su, Yi Yan, Bei Feng, Wen Mao, Yuyan Zhang, Xiaojian Wang, Zhuoming Xu, Hao ZhangShanghai Children’s Medical Center and Shanghai Jiao Tong University. Fuwai Hospital and Chinese Academy of Medical Sciences and Peking Union Medical College. Ludwig Maximilian University Munich. artner site Munich Heart Alliance. Nanjing Novlead Biotechnology

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Oral hymecromone decreases hyaluronan in human study participants

Joelle I. Rosser, Nadine Nagy, Riya Goel, Gernot Kaber, Sally Demirdjian, Jamie Saxena, Jennifer B. Bollyky, Adam R. Frymoyer, Ana E. Pacheco-Navarro, Elizabeth B. Burgener, Jayakumar Rajadas, Zhe Wang, Olga Arbach, Colleen E. Dunn, Anissa Kalinowski, Carlos E. Milla, Paul L. BollykyStanford University. UCSF School of Pharmacy. Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität Zu Berlin

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Response categorization and outcomes in extremely premature infants born at 22-26 weeks gestation that received inhaled nitric oxide for hypoxic respiratory failure

Timothy J. Boly, John M. Dagle, Jonathan M. Klein, Danielle R. Rios, Patrick J. McNamara, Regan E. GiesingerUniversity of Iowa.United States Journal of PerinatologyJ Perinatol 2023; 43: 324-331DOI: 10.1038/s41372-022-01582-4 AbstractObjective: To evaluate the outcomes of extremely premature infants who received inhaled nitric oxide(iNO) for hypoxic respiratory failure(HRF).Study design: Retrospective analysis of 107 infants born 22-26 weeks gestation who

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Aortopulmonary Collateral Arteries in Noncyanotic Congenital Heart Disease

Fan Yang, Qiang Wang, Hong Meng, Ge-Jun Zhang, Ju-Xian YangFuwai Hospital, Fuwai Yunnan Cardiovascular Hospital and Chinese Academy of Medical Sciences and Peking Union Medical College.China Annals of Thoracic SurgeryAnn Thorac Surg 2022; 113: e125-e127DOI: 10.1016/j.athoracsur.2021.04.062 AbstractDevelopment of major aortopulmonary collateral arteries are strongly associated with cyanotic congenital heart disease. However, they have rarely been reported

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Sex as an Independent Risk Factor for Venous Thromboembolism in Sickle Cell Disease: A Cross-Sectional Study

Andrea H. Roe, Arden McAllister, Corinne Kete, Hilary Whitworth, Courtney A. Schreiber, Farzana A. SayaniUniversity of Pennsylvania Perelman School of Medicine. The Children’s Hospital of Philadelphia.United States Journal of Women’s HealthJ Womens Health 2022; 31: 1467-1471DOI: 10.1089/jwh.2022.0046 AbstractVenous thromboembolism (VTE) affects up to 25% of individuals with sickle cell disease (SCD), but risk factors are not

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Altered Lung Microbiome and Metabolome Profile in Children With Pulmonary Arterial Hypertension Associated With Congenital Heart Disease

Runwei Ma, Liming Cheng, Yi Song, Yi Sun, Wenting Gui, Yao Deng, Chao Xie, Min LiuFuwai Yunnan Cardiovascular Hospital. Kunming Children’s Hospital. China Frontiers in MedicineFront Med 2022; 9: DOI: 10.3389/fmed.2022.940784 AbstractBackgrounds: Pulmonary arterial hypertension (PAH) is characterized by progressive pulmonary vascular functional and structural changes, resulting in increased pulmonary vascular resistance and eventually right heart failure

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Treatment and prognosis of Scimitar syndrome: A retrospective analysis in a single center of East China

Kai Wang, Xinyi Xu, Tingliang Liu, Wei Gao, Ying GuoShanghai Children’s Medical Center and Shanghai Jiao Tong University. The First Affiliated Hospital of Wenzhou Medical University.China Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2022; DOI: 10.3389/fcvm.2022.973796 AbstractBackground: Scimitar syndrome is a rare congenital cardiovascular malformation; its optimal management remains controversial. This study aims to present the clinical experience

Treatment and prognosis of Scimitar syndrome: A retrospective analysis in a single center of East China Read More »

Implications for the metabolic fate of oral glutamine supplementation within plasma and erythrocytes of patients with sickle cell disease: A pharmacokinetics study

Claudia R. Morris, Frans A. Kuypers, Robert Hagar, Sandra Larkin, Lisa Lavrisha, Augusta Saulys, Elliott P. Vichinsky, Jung H. SuhEmory University School of Medicine and Children’s Healthcare of Atlanta. UCSF-Benioff Children’s Hospital Oakland.United States Complementary Therapies in MedicineComplement Ther Med 2022; 64: DOI: 10.1016/j.ctim.2022.102803 AbstractObjectives: L-Glutamine is FDA-approved for sickle cell disease (SCD), yet the mechanism(s)-of-action are

Implications for the metabolic fate of oral glutamine supplementation within plasma and erythrocytes of patients with sickle cell disease: A pharmacokinetics study Read More »

Heterozygous Tropomodulin 3 mice have improved lung vascularization after chronic hypoxia

Tsering Stobdan, Pritesh P. Jain, Mingmei Xiong, Vineet Bafna, Jason X.-J. Yuan, Gabriel G. HaddadUniversity of California San Diego. Rady Children’s Hospital.United States Human Molecular GeneticsHum Mol Genet 2022; 31: 1130-1140DOI: 10.1093/hmg/ddab291 AbstractThe molecular mechanisms leading to high-altitude pulmonary hypertension (HAPH) remains poorly understood. We previously analyzed the whole genome sequence of Kyrgyz highland population and

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