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Notch signalling in healthy and diseased vasculature

Francesca Del Gaudio, Dongli Liu, Urban LendahlKarolinska Institutet. The First Affiliated Hospital of Guangxi Medical University.Sweden and China Open BiologyOpen Biol 2022; 12: DOI: 10.1098/rsob.220004 AbstractNotch signalling is an evolutionarily highly conserved signalling mechanism governing differentiation and regulating homeostasis in many tissues. In this review, we discuss recent advances in our understanding of the roles that […]

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Hippo signaling pathway and respiratory diseases

Weifeng Tang, Min Li, Xiaoting Yangzhong, Xifeng Zhang, Anju Zu, Yunjiao Hou, Lin Li, Shibo SunFirst Affiliated Hospital and Kunming Medical University. China Cell Death DiscoveryCell Death Discov 2022; 8: DOI: 10.1038/s41420-022-01020-6 AbstractThe hippo signaling pathway is a highly conserved evolutionary signaling pathway that plays an important role in regulating cell proliferation, organ size, tissue development,

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Physiologically based pharmacokinetic modelling of treprostinil after intravenous injection and extended-release oral tablet administration in healthy volunteers: An extrapolation to other patient populations including patients with hepatic impairment

Xuemei Wu, Xiaohan Zhang, Ruichao Xu, Imam Hussain Shaik, Raman VenkataramananUniversity of Pittsburgh School of Pharmacy. Fujian Medical University Union Hospital. University of Virginia. University of Pittsburgh School of Medicine.United States and China British Journal of Clinical PharmacologyBrit J Clin Pharmacol 2022; 88: 587-599DOI: 10.1111/bcp.14966 AbstractAims: Pulmonary arterial hypertension (PAH) is characterized by increased pulmonary arterial pressure,

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Risk factors that affect the degree of bronchopulmonary dysplasia in very preterm infants: a 5-year retrospective study

Tingting Yang, Qianqian Shen, Siyu Wang, Tianfang Dong, Liang Liang, Fan Xu, Youfang He, Chunlei Li, Fang Luo, Jiahong Liang, Chunhui Tang, Jinghui YangKunming University of Science and Technology. The First People’s Hospital of Yunnan Province. Dali University. The First Hospital of Kunming. Yunnan University of Traditional Chinese Medicine. The Affiliated Hospital of Kunming University

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Construction and Evaluation of a Bio-Engineered Pump to Enable Subpulmonary Support of the Fontan Circulation: A Proof-of-Concept Study

Christopher R. Broda, P. Alex Smith, Yaxin Wang, Hamsini Sriraman, Peter S. Owuor, Luiz C. Sampaio, Iki Adachi, Doris A. Taylor, Christopher R. Broda, P. Alex Smith, Yaxin Wang, Hamsini Sriraman, Peter S. OwuorBaylor College of Medicine and Texas Children’s Hospital. Texas Medical Center. Texas Heart Institute. Pennsylvania State University. University of Texas Health Science

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Type 2 immune polarization is associated with cardiopulmonary disease in preterm infants

Jason C. Lao, Christine B. Bui, Merrin A. Pang, Steven X. Cho, Ina Rudloff, Kirstin Elgass, Jan Schroder, Anton Maksimenko, Niamh E. Mangan, Malcolm R. Starkey, Elisabeth M. Skuza, Yu B. Y. Sun, Friederike Beker, Clare L. Collins, Omar F. Kamlin, Kai Konig, Atul Malhotra, Kenneth Tan, Chritiane Theda, Morag J. Young, Catriona A. McLean,

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Cardiovascular magnetic resonance in autoimmune rheumatic diseases: a clinical consensus document by the European Association of Cardiovascular Imaging

S. Mavrogeni, A. Pepe, K. R. Nijveldt, N. Ntusi, L.M. Sierra-Galan, Bratis, J. Wei, M. Mukherjee, G. Markousis-Mavrogenis, L. Gargani, L.E. Sade, N. Ajmone-Marsan, M. P. Seferovic, E. Donal, Nurmohamed, M. Matucci Cerinic, P. Sfikakis, G. Kitas, J. Schwitter, J. A. C. Lima, Dana Dawson, Marc Dweck, Kristina H. Haugaa, Niall Keenan, James Moon, Ivan

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Plasma level of antimony correlates with pulmonary arterial hypertension severity

Karim El-Kersha, C. Danielle Hopkins, Xiaoyong Wu, Shesh N. Rai, Lu Caie, Jiapeng HuangUniversity of Nebraska Medical Center. University of Louisville School of Medicine. University of Louisville. United States Current Research in ToxicologyCurr Res Toxicol 2022; 3: DOI: 10.1016/j.crtox.2022.100080 AbstractIt is unknown if environmental antimony exposure influences pulmonary arterial hypertension (PAH) and right ventricular function. We

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Maternal and fetal outcomes of pregnant women with pulmonary arterial hypertension associated with congenital heart disease in Beijing, China: A retrospective study

Yang Liu, Yanna Li, Jun Zhang, Dawei Zhang, Jiachen Li, Yichen Zhao, Kemin Liu, Xiaolong Ma, Chen Bai, Hong Gu, Xiangming Fan, Jiangang WangBeijing Anzhen Hospital Affiliated to Capital Medical University. China Pulmonary CirculationPulm Circ 2022; 12: DOI: 10.1002/pul2.12079 AbstractAs pulmonary arterial hypertension associated with congenital heart disease (PAH-CHD) may increase maternal and fetal risk, this

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Late-onset cblC deficiency around puberty: a retrospective study of the clinical characteristics, diagnosis, and treatment

Zhehui Chen, Hui Dong, Yupeng Liu, Ruxuan He, Jinqing Song, Ying Jin, Mengqiu Li, Yi Liu, Xueqin Liu, Hui Yan, Jianguang Qi, Fang Wang, Huijie Xiao, Hong Zheng, Lulu Kang, Dongxiao Li, Yao Zhang, Yanling YangPeking University First Hospital. Peking University People’s Hospital. Beijing Children’s Hospital Affiliated to Capital Medical University. China-Japan Friendship Hospital. First

Late-onset cblC deficiency around puberty: a retrospective study of the clinical characteristics, diagnosis, and treatment Read More »

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