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Simvastatin restores pulmonary endothelial function in the setting of pulmonary over-circulation

Jason T. Boehme, Xutong Sun, Qing Lu, Jubilee Barton, Xiaomin Wu, Wenhui Gong, Gary W. Raff, Sanjeev A. Datar, Ting Wang, Jeffrey R. Fineman, Stephen M. BlackUniversity of California San Francisco. Howard Wertheim College of Medicine and Florida International University. University of Arizona Health Sciences. University of California Davis. United States Nitric OxideNitric Oxide 2023; […]

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Low-dose diazoxide is safe and effective in infants with transient hyperinsulinism

Neha Malhotra, Daphne Yau, Annaruby Cunjamalay, Buddhi Gunasekara, Athanasakopoulou S., Clare Gilbert, Kate Morgan, Mehul Dattani, Antonia DastamaniGreat Ormond Street Hospital for Children. University of Saskatchewan. Medical School of Queen Mary University.United Kingdom and Canada Clinical EndocrinologyClin Endocrinol 2023; DOI: 10.1111/cen.14987 AbstractObjective: Transient hyperinsulinism (THI) is the most common form of recurrent hypoglycaemia in neonates beyond the

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The novel roles of YULINK in the migration, proliferation and glycolysis of pulmonary arterial smooth muscle cells: implications for pulmonary arterial hypertension

Yi‑Chia Wu, Wei‑Ting Wang, Ming‑Chun Yang, Yu‑Tsun Su, Jwu‑Lai Yeh, Jong‑Hau Hsu, Jiunn‑Ren WuKaohsiung Medical University Hospital and Kaohsiung Medical University. Kaohsiung Municipal Ta-Tung Hospital. E-Da Hospital and I-Shou University.Taiwan Biological ResearchBiol Res 2023; DOI: 10.1186/s40659-023-00480-z AbstractBackground: Abnormal remodeling of the pulmonary vasculature, characterized by the proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs) along

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Long-term outcomes and immune profiling in children with multisystem inflammatory syndrome (MIS-C)

Indira Jaxybayeva, Riza Boranbayeva, Minira Bulegenova, Natalya Urazalieva, Valentin Gerein, Lyazat ManzhuovaAsfendiyarov Kazakh National Medical University. Goethe University Hospital.Kazakhstan and Germany Acta BiomedicaActa Biomed 2023;DOI: 10.23750/abm.v94i6.14788 AbstractBackground and aim: Existing follow-up data after MIS-C is limited.Purpose of the study: to investigate the long-term consequences in children who have undergone MIS-C.Methods: The retrospective study included 93 children. The identified changes

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Inhalable Nitric Oxide Delivery Systems for Pulmonary Arterial Hypertension Treatment

Yoogyeong Oh, Kyungtae Park, Sungwon Jung, Moonhyun Choi, Taihyun Kim, Yoojin Kim, Yoojin Lee, Jae Young Choi, Yang-Hee Kim, Se Yong Jung, Jinkee HongYonsei University College of Medicine. University of Southampton.Republic of Korea and United Kingdom SmallSmall 2023; DOI: 10.1002/smll.202308936 AbstractPulmonary arterial hypertension (PAH) is a severe medical condition characterized by elevated blood pressure in the

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Shape of Pulmonary Artery Doppler Flow Profile and Right Ventricular Hemodynamics in Neonates

Sébastien Joye, Soume Bhattacharya, Ashraf Kharrat, Bonny Jasani, Regan E. Giesinger, Patrick J. McNamara, Amish JainLausanne University Hospital. LHSC Children’s Hospital. Mount Sinai Hospital and University of Toronto. Hospital of Sick Children. University of Iowa. Switzerland, Canada and United States Journal of PediatricsJ Pediatr 2023; DOI: 10.1016/j.jpeds.2023.113864 AbstractObjectives: To characterize pulmonary artery Doppler flow profile (PAFP) patterns

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Thirty years of surgical management of pediatric pulmonary hypertension: mid-term outcomes following reverse Potts shunt and transplantation

Estibaliz Valdeomillos, Jerome Le Pavec, Marion Audie, Laurent Savale, Xavier Jais, David Montani, Oliver Sitbon, Severine Feuillet, Olaf Mercier, Jerome Petit, Marc Humbert, Elie Fadel, Emre Belli, Sebastien HascoetCentre de Référence Malformations Cardiaques Congénitales Complexes M3C, HÔpital Marie Lannelongue, Groupe Hospitalier Paris-Saint Joseph and Université Paris Saclay. France Journal of Thoracic and Cardiovascular SurgeryJ Thorac

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Diminished TMEM 100 Expression in a Newborn With Acinar Dysplasia and a Novel TBX4 Variant: A Case Report

Przemyslaw Szafranski, Silvia Patrizi, Thomasz Gambin, Bushra Afzal, Emily Schlotterbeck, Justyna A. Karolak, Gail Deutsch, Drucilla Roberts, Pawel StankiewiczBaylor College of Medicine. Brigham and Women’s Hospital, Newton-Wellesley Hospital and Harvard Medical School. Warsaw University of Technology. Massachusetts General Hospital.  Poznan University of Medical Sciences. University of Washington School of Medicine.United States and Poland Pediatric and

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Neonatal sepsis and cardiovascular dysfunction I: mechanisms and pathophysiology

Sophie M. Duignan, Satyan Lakshminrusimha, Kathryn Armstrong, Willem P. de Boode, Afif El-Khuffash, Orla Franklin, Eleanor J. Molloy, Infection, Inflammation, Immunology and Immunisation Section of the European Society for Pediatric Research (ESPR)Children’s Health Ireland at Crumlin. University of California, Davis Children’s Hospital. British Columbia Children’s Hospital. Radboud University Medical Center and Amalia Children’s Hospital. Royal

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Acute exacerbation of pulmonary arterial hypertension after COVID-19 vaccination

Nagomi Nakamura, Takashi Murakami, Takumi Ishiodori, Yoshihiro Nozaki, Kazuo Imagawa, Hitoshi Horigome, Hidetoshi TakadaUniversity of Tsukuba Hospital. Ibaraki Children’s Hospital.Japan Pediatrics InternationalPediatr Int 2023; DOI: 10.1111/ped.15711 AbstractAbstract Not Available CategoryEnvironmental Factors Associated with Pulmonary Vascular Disease Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Filed (PHiled). Greater than 1-2 years since publication Article Access

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